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تاثیر هشت هفته تمرین HIRT بر سطوح سرمی کمرین، واسپین و فاکتورهای موثر در پاتوژنز دیابت در مردان پیش دیابتی چاق و اضافه وزن

نوع مقاله : مقاله پژوهشی Released under CC BY-NC 4.0 license I Open Access I

نویسندگان

1 گروه تربیت بدنی و علوم ورزشی، دانشکدة علوم انسانی، دانشگاه کاشان، کاشان، ایران.

2 نویسندة مسئول: گروه تربیت بدنی و علوم ورزشی، دانشکدة علوم انسانی، دانشگاه کاشان، کاشان، ایران

3 گروه فیزیولوژی ورزشی، دانشکدة علوم تربیتی و روانشناسی، دانشگاه محقق اردبیلی، اردبیل، ایران.

10.22059/jsb.2024.373767.1629

چکیده

مقدمه: بیان مولکول‌های زیست‌فعال کمرین و واسپین از طریق ارتباط بین بافت چربی و سایر سیستم‌های بیولوژیکی بدن انجام می‌گیرد که در بیماری‌زایی سندروم متابولیک و پاتوژنز چاقی و دیابت نقش دارند. هدف از تحقیق حاضر بررسی تأثیر هشت هفته تمرین HIRT بر سطوح سرمی کمرین، واسپین و فاکتورهای موثر در پاتوژنز دیابت در مردان پیش‌دیابتی چاق و اضافه وزن بود.
روش پژوهش: در این تحقیق نیمه‌تجربی 30 نفر از مردان چاق پیش‌دیابتی (30 تا 45 سال) به‌صورت تصادفی به دو گروه تجربی و کنترل (هر گروه 15 نفر)، تقسیم شدند. گروه تجربی به مدت هشت هفته و هر هفته سه جلسه به مدت 60 دقیقه در برنامة HIRT با شدت 80 تا 85 درصد یک تکرار بیشینه شرکت کردند. سطوح سرمی کمرین، واسپین و شاخص‌های دیابت در دو نوبت پیش و پس‌آزمون اندازه‌گیری شد.
یافته‌ها: نتایج تحلیل کوواریانس نشان داد مقادیر کمرین (001/0=P)، واسپین (001/0=P)، انسولین (001/0=P)، گلوکز (001/0=P) و مقاومت به انسولین (001/0=P)، در گروه تجربی نسبت به گروه کنترل کاهش معناداری یافت. نتایج درون‌گروهی t زوجی نیز کاهش معنادار کمرین (001/0=P، 90/0- درصد)، واسپین (003/0=P، 6/16- درصد)، انسولین (001/0=P، 5/17- درصد)، گلوکز (001/0=P، 1/19- درصد) و مقاومت به انسولین (001/0=P، 8/40- درصد) در پاسخ به پروتکل تمرین را نشان داد (P<0.05).
نتیجه‌گیری: احتمالاً تمرینات HIRT می‌تواند بر شاخص‌های کمرین، واسپین و برخی فاکتورهای مؤثر در دیابت و ترکیب بدنی در مردان چاق پیش دیابتی تأثیر مفیدی داشته باشد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The Effect of Eight Weeks of HIRT Training on the Serum Levels of Chemerin, Vaspin, and Factors Affecting the Pathogenesis of Diabetes in Obese and Overweight Pre-Diabetic Men

نویسندگان [English]

  • Ahmed Al-Azi 1
  • mohammad javad pourvaghar 2
  • mohammad ebrahim bahram 3

1 Department of Sports Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran.

2 Corresponding Author, Department of Sports Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran.

3 Department of Exercise Physiology, Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.

چکیده [English]

Introduction: The expression of chemerin and Vaspin bioactive molecules is done through the communication between adipose tissue and other biological systems of the body, which play a role in the pathogenesis of metabolic syndrome, obesity, and diabetes. This study aimed to investigate the effect of eight weeks of HIRT training on the serum levels of Chemerin, and Vaspin, and factors effective in the pathogenesis of diabetes in obese and overweight pre-diabetic men.
Methods: In this semi-experimental study, 30 pre-diabetic obese men (30 to 45 years old) were randomly assigned to two experimental and control groups (15 people in each group). The experimental group participated in the HIRT program with an intensity of 80-85% of 1 repetition maximum for 8 weeks and three sessions each week for 60 minutes. The serum levels of Chemerin, Vaspin, and diabetes factors were measured on two occasions pre-test and post-test.
Results: The results of covariance analysis showed that the values of Chemerin (P=0.001), Vaspin (P=0.001), insulin (P=0.001), glucose (P=0.001), and insulin resistance (P=0.001), were significantly reduced in the experimental group compared to the control group. The intra-group results of paired t-test also showed a significant decrease in Chemerin (P=0.001, -0.90 percent), Vaspin (P=0.003, -16.6 percent), insulin (P=0.001, -17.5 percent), glucose (P=0.001, -19.1%), and insulin resistance (P=0.001, -40.8%) in response to the training protocol (P<0.05).
Conclusion: In general, HIRT training can have a beneficial effect on Chemerin, Vaspin, and some factors affecting diabetes and body composition in pre-diabetic obese men.

کلیدواژه‌ها [English]

  • HIRT
  • Chemerin
  • Vaspin
  • Overweight
  • Pathogenesis of Diabetes
مراجع

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نشریه علوم زیستی ورزشی
دوره 16، شماره 1 - شماره پیاپی 99
فروردین 1403
صفحه 61-75
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  • تاریخ دریافت: 19 اسفند 1402
  • تاریخ بازنگری: 14 اردیبهشت 1403
  • تاریخ پذیرش: 26 اردیبهشت 1403
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