تأثیر تمرین تناوبی با شدت‌های مختلف روی سطوح پلاسمایی اورکسین A-، نیمرخ لیپیدی و استقامت قلبی تنفسی زنان دارای اضافه‌وزن و چاق

نوع مقاله: مقاله پژوهشی

نویسندگان

1 کارشناس ارشد فیزیولوژی ورزشی، گروه فیزیولوژی ورزشی، دانشکدة علوم ورزشی، دانشگاه اصفهان، اصفهان، ایران

2 دانشیار، گروه فیزیولوژی ورزشی، دانشکدة علوم ورزشی، دانشگاه اصفهان، اصفهان، ایران

چکیده

هدف کلی پژوهش حاضر بررسی تأثیر دو شیوۀ تمرین تناوبی با شدت بالا و متوسط روی سطوح پلاسمایی اورکسین-A، نیمرخ لیپیدی و استقامت قلبی- تنفسی زنان دارای اضافه‌وزن و چاق بود. 24 زن با دامنۀ سنی 45-25 سال به شکل داوطلبانه و غیرتصادفی به سه گروه تمرین تناوبی با شدت زیاد (9n=،kg/m2  45/3 ±61/29(BMI=، شدت متوسط (8n= ؛ kg/m2  83/3 ± 19/28 BMI=) و کنترل (7n= ،kg/m2 71/4 ± 18/29BMI=) تقسیم شدند. برنامۀ تمرینی به مدت 8 هفته/ سه جلسه در هفته با شدت90-75% برای گروه HIIT و80-60%ضربان قلب بیشینه برای گروهMIIT اجرا شد. نتایج حاکی از کاهش معناداری در سطوح کلسترول تام و افزایش معناداری در استقامت قلبی- تنفسی گروه‌های تمرینی بود (05/0P≤). از سوی دیگر، افزایش و تغییراتی در سطوح پلاسمایی اورکسین، کاهش تری‌گلیسیرید، LDL و درصد چربی بدن در گروه‌های تمرینی در مقایسه با گروه کنترل مشاهده شد، اما این تغییرات از نظر آماری معنادار نبود (05/0≤P). همچنین سطوح HDL در گروه HIIT افزایش و در گروه MIIT کاهش نشان داد، که در هیچ‌کدام از گروه‌ها این تغییرات معنادار نبود (05/0≤P). به‌نظر ‌می‌رسد تمرین تناوبی با شدت‌های مختلف موجب افزایش سطوح پلاسمایی اورکسین و بهبود برخی شاخص‌های نیمرخ لیپیدی، درصد چربی بدن و استقامت قلبی تنفسی در زنان دارای اضافه‌وزن و چاق شده است، اما این بهبودی در گروه HIIT بارزتر بود.

کلیدواژه‌ها


عنوان مقاله [English]

The Effect of Interval Training with Different Intensities on Plasma Levels of Orexin –A, Lipid Profile and Cardiorespiratory Endurance of Overweight and Obese Women

نویسندگان [English]

  • Hajar Allahverdi 1
  • VAZGEN MINASIAN 2
1 MSc of Exercise Physiology, Department of Exercise Physiology, Faculty of Sport Sciences, University of Isfahan, Isfahan, Iran
2 Associate Professor, Department of Exercise Physiology, Faculty of Sport Sciences, University of Isfahan, Isfahan, Iran
چکیده [English]

The main aim of this study was to evaluate the effect of high and medium intensity interval training on plasma levels of Orexin-A, lipid profile and cardiorespiratory endurance of overweight and obese women. 24 women (age range 25-45 years) volunteered and were non-randomly divided into HIIT (n=9, BMI= 29.61±3.45 kg.m2), MIIT (n=8, BMI= 28.19±3.83 kg.m2) and control (n=7, BMI=29.18±4.71 kg.m2) groups. The HIIT protocol was conducted with %75-90 of maximum HR and MIIT protocol with %60-80 of maximal HR for 8 weeks and 3 sessions per week. The findings showed a significant reduction in total cholesterol level and a significant increase in cardiorespiratory endurance of the training groups (P≤0.05). On the other hand, plasma Orexin levels increased and changed and triglyceride, LDL and body fat percent decreased in training groups compared with the control group, but these changes were not statistically significant (P≥0.05). Also, the HDL levels increased in HIIT group while they decreased in MIIT group; these changes were not statistically significant in any of the groups (P≥0.05). It seems that the interval training with different intensities increased Orexin plasma levels and improved some markers of lipid profile, body fat percent and cardiorespiratory endurance in overweight and obese women, but this improvement was more sensible in HIIT group. 

کلیدواژه‌ها [English]

  • Aerobic capacity
  • interval training
  • lipid profile
  • obese women
  • Orexin-A
1. Aghaie Meybodi HR, Azizi F. The assessment of relation between lipid distribution and weight change with diabetes incidence in a group of Tehran, district 13 population (In Persian). Pejouhesh dar Pezeshki (Research in Medicine). 2008;32(2):105-13.

2. Rahmani A, Sayehmiri K, Asadollahi K, Sarokhani D, Islami F, Sarokhani M. Investigation of the prevalence of obesity in Iran: A systematic review and meta-analysis study (In Persian). Acta Medica Iranica. 2015;53(10):596-607.

3. Hao Y-y, Yuan H-w, Fang P-h, Zhang Y, Liao Y-x, Shen C, et al. Plasma orexin-A level associated with physical activity in obese people. Eating and Weight Disorders-Studies on Anorexia, Bulimia and Obesity. 2017;22(1):69-77.

4. Perez-Leighton CE, Billington CJ, Kotz CM. Orexin modulation of adipose tissue. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease. 2014;1842(3):440-5.

5. Lee R. The Effect of Hindbrain Orexin A Signaling on Brown Adipose Tissue Thermogenesis and Physical Activity. 2014. Retrieved from the University of Minnesota Digital Conservancy, http://hdl.handle.net/11299.

6. Zink AN, Perez-Leighton CE, Kotz CM. The orexin neuropeptide system: physical activity and hypothalamic function throughout the aging process. Frontiers in systems neuroscience. 2014 Nov 4; 8:211.

7. Heinonen M, Purhonen A, Mäkelä K, Herzig K. Functions of orexins in peripheral tissues. Acta Physiologica. 2008;192(4):471-85.

8. Perez-Leighton CEB, Charles J and Kotz, Catherine M. Orexin modulation of adipose tissue. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease. 2014;1842(3):440-5.

9. Baranowska B, Wolinska-Witort E, Martynska M, Chmielowska M, Baranowska-Bik A. Plasma orexin A, orexin B, leptin, neuropeptide Y (NPY) and insulin in obese women. Neuroendocrinology Letters. 2005;26(4):293-6.

10. Kotz CM. Integration of feeding and spontaneous physical activity: role for orexin. Physiology & behavior. 2006;88(3):294-301.

11. Azdari ZH, Elahdadi SM. A Reveiw of Reserch and Articels Published on Orexin in the Last Decade (In Persian).Journal of Torbatheydariyeh University of Medical Sciences (Journal of Torbat Chemes). 2014;2(1):60-68.

12. Alizadeh AA, Rahmani-Nia F, Mohebbi H, Zakerkish M. Acute Aerobic Exercise and Plasma Levels of Orexin A, Insulin, Glucose, and Insulin Resistance in Males With Type 2 Diabetes. Jundishapur Journal of Health Sciences. 2016;8(1); e32217.

13. Martins PJ, D'Almeida V, Pedrazzoli M, Lin L, Mignot E, Tufik S. Increased hypocretin-1 (orexin-a) levels in cerebrospinal fluid of rats after short-term forced activity. Regulatory peptides. 2004;117(3):155-8.

14. Wu M-F, Nienhuis R, Maidment N, Lam H, Siegel J. Cerebrospinal fluid hypocretin (orexin) levels are elevated by play but are not raised by exercise and its associated heart rate, blood pressure, respiration or body temperature changes. Archives italiennes de biologie. 2011;149(4):492.

15. Chieffi S, Messina G, Villano I, Messina A, Esposito M, Monda V, et al. Exercise influence on hippocampal function: possible involvement of orexin-A. Frontiers in physiology. 2017;8:85.

16. Burgomaster KAC, Naomi M. Phillips, Stuart M. Benton, Carley R. Bonen, Arend and Gibala, Martin J. Divergent response of metabolite transport proteins in human skeletal muscle after sprint interval training and detraining. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2007;292(5):1970-6.

17. Racil G, Ounis OB, Hammouda O, Kallel A, Zouhal H, Chamari K, et al. Effects of high vs. moderate exercise intensity during interval training on lipids and adiponectin levels in obese young females. European journal of applied physiology. 2013;113(10):2531-40.

18- Roger Ston & Thomas Reilly. Kinantheropometry and Exercise physiology Laboratory Manual (Tests. Procedures and data). 3 ed: Routledge; 2009. 115-125.

19. Gustavo S, Nórton Luis O, Luísa A, Jorge M, José O, and José Carlos. Calculation and validation of models for estimating VO 2max from the 20-m shuttle run test in children and adolescents, Arch Exerc Health Dis. 2012: 3 (1-2):145-152

20. Vincent W.J, Statistics in Kinesiology, translated By: Minasian V. Tehran, Elm-o- Harekat Pub., 2009 (In Persian).

21. Mohammadhassani FE, Alireza and Jafari, Afshar. The effects of endurance training and high intensity interval training on orexin-A and anthropometric parameters in obese adolescent boys (In Persian). Journal of School of Public Health and Institute of Public Health Research. 2015;13(1):99-112.

22. Bronský J, Nedvidkova J, Zamrazilova H, Pechova M. Dynamic changes of orexin A and leptin in obese children during body weight reduction. Physiological research. 2007;56(1):89.

23. Funato H, Tsai AL, Willie JT, Kisanuki Y, Williams SC, Sakurai T, et al. Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity. Cell metabolism. 2009;9(1):64-76.

24. Messina GDB, Giovanni. Viggiano, Andrea. De Luca, Vincenzo. Monda, Vincenzo. Messina, Antonietta. et al., Exercise increases the level of plasma orexin A in humans. Journal of Basic and Clinical Physiology and Pharmacology. 2016;27(6):611-6.

25. Zhang H, K Tong T, Qiu W, Wang J, Nie J, He Y. Effect of high-intensity interval training protocol on abdominal fat reduction in overweight Chinese women: a randomized controlled trial. Kineziologija. 2015;47(1):57-66.

26. Heydari M, Freund J, Boutcher SH. The effect of high-intensity intermittent exercise on body composition of overweight young males. Journal of obesity. 2012; 480467, 8

27. Abdolmaleki A, Samavatisharif M, Nikbakht Nasabadi P, Amini R. The Effects of 12 Weeks of Low-volume High-intensity Interval Training and Traditional Continuous Exercise Training on Adiponectin Level and Lipids Profile in Obese Young Men (In Persian). Journal of Ilam Univercity of Medical of Sciences. 2014;22(5): 150-159.

28. Batacan RB, Duncan MJ, Dalbo VJ, Tucker PS, Fenning AS. Effects of high-intensity interval training on cardiometabolic health: a systematic review and meta-analysis of intervention studies. Br J Sports Med. 2016;9 (58)8-14.

29 Whyte LJ, Gill JM, Cathcart AJ. Effect of 2 weeks of sprint interval training on health-related outcomes in sedentary overweight/obese men. Metabolism. 2010;59(10):1421-8.

30. Gibala MJ, Little JP, MacDonald MJ, Hawley JA. Physiological adaptations to low‐volume, high‐intensity interval training in health and disease. The Journal of physiology. 2012;590(5):1077-84.