نوع مقاله : مقاله پژوهشی Released under CC BY-NC 4.0 license I Open Access I

نویسندگان

1 دانشجوی دکتری تخصصی بیوشیمی و متابولیسم ورزشی، گروه فیزیولوژی ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران

2 . دانشیار گروه فیزیولوژی ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران

3 استادیار گروه فیزیولوژی ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران

4 . استاد گروه فیزیولوژی ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران

چکیده

چکیده
اطلاعات اندکی دربارۀ آثار تمرین هوازی با شدت بالا (HIT) و استفاده از مکمل آرژنین بر هورمون های تنظیم کننده اشتها، همراه با کنترل تغذیه در نوجوانان چاق وجود دارد. هدف ما بررسی تاثیر 8 هفته تمرین هوازی با شدت بالا و مصرف آرژنین بر تغییرات هورمونی لپتین و پروتئین وابسته به آگوتی پسران نوجوان چاق بود.
در شرایط ایزوانرژیک 20 نوجوان چاق براساس توان هوازی به دو گروه 1) تمرینHIT و دارونما (10 نفر) و 2) تمرینHIT به همراه مکمل آرژنین(10 نفر) تقسیم شدند. پیش از مداخله پروتکل تمرین و 48 ساعت پس از آخرین جلسه تمرین سطوح هورمون های تنظیم کننده اشتها در خون اندازه گیری شدند. برای بررسی تفاوت های درون و بین گروهی به ترتیب از تی استیودنت وابسته و مستقل استفاده شد. نتایج نشان داد که تغییرات درون و بین گروهی مقادیر لپتین و پروتئین وابسته به آگوتی نسبت به مقادیر پایه، در گروه های تمرین و دارونما و تمرین به همراه مکمل آرژنین معنادار نیست(05/0≤P).
نتیجه گیری: هر دو مدل تمرین و مکمل-تمرین اثرات متفاوتی در تنظیم سیگنال های اشتها در نوجوانان پسر چاق دارند. گرچه ممکن است نتایج این آثار در برخی شاخص ها محسوس نباشد.

کلیدواژه‌ها

عنوان مقاله [English]

Effect of High Intensity Aerobic Exercise Training and Arginine supplementation on Hormonal Changes in Leptin and Agouti-Related Protein (AGRP) in Obese Adolescent Boys

نویسندگان [English]

  • Tohid Mabhout Moghadam 1
  • Mehrdad Fathei 2
  • Reza Attarzadeh 3
  • Amir Rashid lamir 2
  • Mohamad Mosaferi 4

1 Ph.D. Student of Biochemistry and Sport Metabolism, Department of Exercise Physiology, Ferdowsi University of Mashhad, Mashhad, Iran

2 Associate Professor-Ferdowsi University of Mashhad

3 assisstant professor

4 Professor, Department of Exercise Physiology, Ferdowsi University of Mashhad, Mashhad, Iran

چکیده [English]

Abstract
There is low information about the effects of high intensity aerobic exercise training (HIT) and the use of supplementation of arginine on appetite regulating hormones, along with nutritional control in obese adolescents. The purpose of this study was to determine the effect of eight weeks of HIT and supplementation of arginine on hormonal changes in leptin and agouti-related protein (AGRP) in obese adolescent boys. In isoenergetic conditions, 20 obese adolescents were according to aerobic power divided into two groups including: 1) HIT and placebo (C, n=10) and HIT with supplementation of arginine (T, n=10).Before Intervention exercise Protocol and 48 hours after the last exercise session, levels of appetite regulating hormones were measured in blood. For Investigation the differences between intra-and intergroup, Independent and independent Student was used. The results intra-and intergroup showed that there was no significant difference between leptin, AGRP compared to baseline levels among and between in C and T groups (P ≥0.05). Conclusion: Both exercise and supplement- exercises have different effects on the regulation of appetite in obese adolescent boys. However, the results of these works may not be palpable in some indices.

کلیدواژه‌ها [English]

  • "High Intensity Aerobic Exercise Training"
  • "Obesity"
  • "Arginine"
  • "Leptin"
  • "Agouti-related protein"
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