نوع مقاله : مقاله پژوهشی Released under CC BY-NC 4.0 license I Open Access I

نویسندگان

1 استادیار گروه فیزیولوژی ورزشی واحد آیت‌الله آملی، دانشگاه آزاد اسلامی، آمل، ایران

2 کارشناس‌ارشد فیزیولوژی ورزشی واحد آیت‌الله آملی، دانشگاه آزاد اسلامی، آمل، ایران

چکیده

 
هدف این تحقیق، بررسی تأثیر یک دوره تمرین هوازی بر فاکتور رشد فیبروبلاست 21 و آدیپونکتین در مردان چاق بود. بدین منظور، 20 مرد چاق انتخاب شدند و به‌طور تصادفی در دو گروه تجربی (سن 34/3±40/29سال، قد 053/0±80/1 سانتی‌متر، وزن 86/7±10/108 کیلوگرم و شاخص تودۀ بدن 68/1±13/33 کیلوگرم بر مجذور متر) و کنترل (سن 39/2±80/29سال، قد 052/0±79/1 سانتی‌متر، وزن 16/8±80/106 کیلوگرم و شاخص تودۀ بدن 93/1± 13/33کیلوگرم بر مجذور متر) قرار گرفتند؛ گروه تجربی تمرینات هوازی با شدت 60 تا 75 درصد ضربان قلب هدف را به مدت هشت هفته انجام دادند. نمونه­های خون آزمودنی­ها پس از 12 تا 14ساعت ناشتایی پیش و پس از هشت هفته جمع­آوری شد. داده­ها با استفاده از آزمون کوواریانس در سطح معنا­داری 05/0P≤ تجزیه‌وتحلیل شدند. نتایج نشان داد که هشت هفته فعالیت هوازی موجب افزایش معنا­دار فاکتور رشد فیبروبلاست 21 (011/0P=)، آدیپونکتین (000/0P=)، عملکرد سلول بتا (008/0P=) و انسولین (000/0P=) در مقایسه با گروه کنترل شد. همچنین سطوح گلوکز پس از هشت هفته فعالیت هوازی در گروه تمرین در مقایسه با گروه کنترل تغییر معنا‌داری نداشت (05/0P>). براساس یافته­های پژوهش حاضر، احتمالاً تمرینات هوازی می­تواند با افزایش سطوح آدیپونکتین و فاکتور رشد فیبروبلاست21 و همچنین تغییرات مطلوب در انسولین سرم، به بهبود عملکرد سلول‌های بتای پانکراس در مردان چاق منجر شود.

کلیدواژه‌ها

عنوان مقاله [English]

The Effect of Aerobic Exercise on Fibroblast Growth Factor 21 and Adiponectin in Obese Men

نویسندگان [English]

  • Asieh Abbassi Daloii 1
  • Abbas Maleki Delarestaghi 2

1 Assistant Professor, Department of Exercise Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran

2 MSc of Exercise Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran

چکیده [English]

 
The aim of this study was to investigate the effect of aerobic exercise on fibroblast growth factor 21 and adiponectin in obese men. 20 obese men were selected and randomly divided into experimental group (age 29.40±3.34 years, height 1.80±0.053 m, weight 108.10±7.86 kg, body mass index 33.13±1.68 kg/m2) and control group (age 29.80±2.39 years, height 1.79±0.052 m, weight 106.80±8.16 kg, body mass index 33.13±1.93 kg/m2). The experimental group performed aerobic exercises with an intensity of 60-75% of target heart rate for 8 weeks. Blood samples were collected after 12 to 14 hours of fasting before and after 8 weeks. Data were analyzed with covariance analysis at P≤0.05. The results showed that 8 weeks of aerobic exercise significantly increased fibroblast growth factor 21 (P=0.011), adiponectin (P=0.000), performance of beta cell (P=0.008) and insulin (P=0.000) compared to the control group. Also, glucose levels had no significant changes after 8 weeks of aerobic exercise in the experimental group compared with the control group (P>0.05). Based on these findings, aerobic exercise may improve the performance of pancreatic beta cells in obese men through an increase in adiponectin and fibroblast growth factor 21 levels and also favorable changes in serum insulin.

کلیدواژه‌ها [English]

  • Adiponectin
  • aerobic exercise
  • fibroblast growth factor 21
  • Obesity
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