نوع مقاله : مقاله پژوهشی
نویسندگان
1 استاد، دانشکدۀ تربیت بدنی و علوم ورزشی، گروه فیزیولوژی ورزشی، دانشگاه تهران، تهران، ایران
2 دانشجوی دکتری، دانشکدۀ تربیت بدنی و علوم ورزشی، گروه فیزیولوژی ورزشی، دانشگاه تهران، تهران، ایران
چکیده
کلیدواژهها
عنوان مقاله [English]
نویسندگان [English]
The aim of this study was to investigate the effectiveness of oxidative stress status resulted from aerobic interval training in type 2 diabetic patients. 24 type 2 diabetic patients under medical treatment (mean age 50.29 ± 6.50 years and BMI 27.21 ± 0.67 kg/m2) were divided into training and control groups. The training program was conducted for 10 weeks, 3 sessions per week and 40 min. with 80% HRmax. Antioxidant indices [superoxide dismutase (SOD) and glutathione peroxidase (GPX)], oxidant index [malondialdehyde (MDA)] and nitrite/nitrate (NOx) were measured. Data were analyzed by two-way ANOVA. Results showed that aerobic interval training significantly increased NOx (P=0.004) and GPX (P=0.001) while it significantly decreased MDA (P=0.029). This training had no significant effect on SOD (P=0.063). In addition, interval training improved aerobic fitness capacity (P=0.005), but metabolic parameters showed no significant effects resulting from aerobic interval training. Aerobic interval training increased NO bioavailability through a decrease in oxidants and an increase in antioxidants. Also, intervals of exercise training improved the oxidation status and endothelial function through an increase in antioxidants and shear stress.
کلیدواژهها [English]