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تأثیر شدت فعالیت مقاومتی بر سطوح ویسفاتین پلاسمایی و ارتباط آن با مقاومت به انسولین و هورمون‌های مرتبط

نوع مقاله : مقاله پژوهشی Released under CC BY-NC 4.0 license I Open Access I

نویسندگان

1 تهران عضو هیئت‌علمی گروه آسیب‌شناسی و حرکات اصلاحی، دانشکدۀ تربیت‌بدنی و علوم ورزشی دانشگاه علامه طباطبایی

2 تهران عضو هیئت‌علمی گروه فیزیولوژی ورزشی، دانشکدۀ تربیت بدنی و علوم ورزشی، دانشگاه شهید بهشتی

3 تهران دانشجوی دکتری فیزیولوژی ورزش، دانشگاه شهید بهشتی

4 بابلسر دانشجوی دکتری فیزیولوژی ورزشی، دانشگاه مازندران

چکیده

هدف از این تحقیق، بررسی پاسخ غلظت پلاسمایی ویسفاتین به شدت فعالیت مقاومتی و ارتباط آن با مقاومت به انسولین، هورمون رشد و اینترلوکین-6 بود. پانزده آزمودنی جوان و سالم با سن 1/4±2/26 سال و وزن 1/9±1/75 کیلوگرم، بعد از جلسات آشنایی و تعیین قدرت بیشینه، سه جلسه فعالیت مقاومتی با شدت‌های30درصد، 55درصد و 80درصد قدرت بیشینه و با حجم‌های یکسان را به فاصلۀ یک هفته و به‌طور تصادفی اجرا کردند. قبل و بلافاصله بعد از فعالیت مقاومتی، از آزمودنی‌ها خون‌گیری به‌عمل آمد و نمونه‌ها برای اندازه‌گیری گلوکز، انسولین، هورمون رشد، اینترلوکین-6 و ویسفاتین آنالیز شدند. نتایج نشان داد که بین پاسخ پلاسمایی ویسفاتین، اینترلوکین-6 و شاخص مقاومت به انسولین به سه شدت متفاوت فعالیت مقاومتی، تفاوت معنی‌داری وجود ندارد (05/0<P). صرف‌نظر از عامل شدت، یک جلسه فعالیت حاد مقاومتی، تأثیر معنی‌داری بر همۀ فاکتورهای اندازه‌گیری‌شده غیر از ویسفاتین داشت (001/0>P). نتایج، ارتباط معنی‌داری را بین هیچ‌یک از فاکتورهای اندازه‌گیری‌شدۀ تحقیق نشان نداد (05/0<P). بر اساس یافته‌های پژوهش حاضر می‌توان نتیجه‌گیری کرد که شدت فعالیت مقاومتی، عامل مؤثری بر پاسخ ویسفاتین، اینترلوکین-6 و شاخص مقاومت انسولین به فعالیت مقاومتی نیست که احتمالاً می‌تواند ناشی از سطح پایین تفاوت انرژی مصرفی طی فعالیت مقاومتی با شدت‌های متفاوت اما حجم یکسان باشد. همچنین، با توجه ‌به بی‌ارتباطی معنی‌دار بین ویسفاتین و مقاومت به انسولین در پاسخ به فعالیت، نمی‌توان این آدیپوکاین را در فرایند مقاومت به انسولین حین فعالیت ورزشی دخیل دانست.

کلیدواژه‌ها

عنوان مقاله [English]

The Effect of Resistance Exercise Intensity on Plasma Visfatin Levels and Its Relationship with Insulin Resistance and Related Hormones

نویسندگان [English]

  • Minoo Bassami 1
  • Sajad Ahmadizad 2
  • Hiwa Rahmani 3
  • Arash Khodamoradi 4

1 Assistant Professor, Department of Sport Injury and Corrective Movements, Faculty of Physical Education and Sports Sciences, Allameh Tabataba’i University, Tehran, Iran

2 Associate Professor, Department of Sport Physiology, Faculty of Physical Education and Sports Sciences, Shahid Beheshti University, Tehran, Iran

3 PhD Student of Sport Physiology, Faculty of Physical Education and Sports Sciences, Shahid Beheshti University, Tehran, Iran

4 PhD Student of Sport Physiology, Faculty of Physical Education and Sports Sciences, Mazandaran University, Babolsar, Iran

چکیده [English]

The aim of the present study was to investigate the response of plasma visfatin to resistance exercise intensity and its relationship with insulin resistance, growth hormone and IL-6. After familiarization and determining their maximum strength (1-RM), 15 healthy young subjects (age: 26.2±4.1 yr, weight: 75.1±9.1 kg) performed three resistance exercise sessions at intensities of 30%, 55% and 80% of 1-RM with equal volumes randomly with a one-week interval. Blood samples were collected before and immediately after the exercise and analyzed to measure glucose, insulin, growth hormone, interlukin-6 (IL-6) and visfatin. Results showed no significant differences among the responses of plasma visfatin, interlukin-6 and insulin resistance index to three different resistance exercise intensities (P>0.05). Irrespective of intensity, a session of resistance exercise had a significant effect (P<0.001) on all variables except for visfatin. No significant relationships were found among all measured variables (P>0.05). Based on the findings of the present study, it could be concluded that resistance exercise intensity was not an effective factor for the response of visfatin, IL-6 and insulin resistance index which might be due to small differences in energy cost of resistance exercise at different intensities but equal volumes. Since there was no significant relationship between visfatin and insulin resistance in response to resistance exercise, this adipokine cannot be involved in insulin resistance during exercise.

کلیدواژه‌ها [English]

  • interlukin-6
  • maximum strength
  • resistance exercise intensity
  • visfatin
مراجع
 
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نشریه علوم زیستی ورزشی
دوره 7، شماره 1 - شماره پیاپی 1
اردیبهشت 1394
صفحه 31-44
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  • تاریخ دریافت: 04 مهر 1392
  • تاریخ بازنگری: 15 اسفند 1392
  • تاریخ پذیرش: 24 اسفند 1392
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