نوع مقاله : مقاله پژوهشی Released under CC BY-NC 4.0 license I Open Access I
نویسندگان
1 دانشجوی دکتری، گروه فیزیولوژی ورزشی، دانشکدة تربیت بدنی و علوم ورزشی، دانشگاه گیلان، رشت، ایران
2 استاد، گروه فیزیولوژی ورزشی، دانشکدة تربیت بدنی و علوم ورزشی، دانشگاه گیلان، رشت، ایران،
3 استاد،گروه زنان و زایمان، دانشکدة پزشکی، دانشگاه علوم پزشکی تهران، تهران، ایران
4 استادیار، گروه علوم تغذیه، پژوهشکدة غدد درون ریز و متابولیسم، دانشگاه علوم پزشکی ایران، تهران، ایران
چکیده
پژوهش حاضر با هدف بررسی تأثیر سه ماه مداخلات سبک زندگی شامل تمرین هوازی غیرنظارت‌شده با شدت متوسط و رژیم غذایی کم‌کالری بر شاخص‌های هورمونی، متابولیکی و آنتروپومتریکی زنان نابارور دارای اضافه وزن و چاق مبتلا به سندروم تخمدان پلی‌کیستیک (PCOS) انجام گرفت. روش این پژوهش تجربی با طرح پیش‌آزمون-پس‌آزمون و رویکرد کاربردی بود. از بین زنان نابارور مبتلا به PCOS مراجعه‌کننده به بیمارستان آرش تهران، 20 نفر (سن 5/2±9/27 سال، وزن 05/8±36/81 کیلوگرم و شاخص تودۀ بدن 97/1±27/30 کیلوگرم بر متر مربع)، به‌عنوان نمونۀ آماری انتخاب و به‌طور تصادفی به دو گروه تجربی (10 نفر) و شاهد (10 نفر) تقسیم شدند. برنامۀ تمرینی و رژیم غذایی براساس مشخصات فردی آزمودنی‌های گروه تجربی تجویز شد. شاخص‌های هورمونی، متابولیکی و آنتروپومتریکی آزمودنی‌ها پیش و پس از سه ماه اندازه‌گیری شد. مقایسۀ درون‌گروهی با آزمون t همبسته و مقایسۀ بین‌گروهی با آزمون آنکوا در نرم‌افزار SPSS صورت گرفت (05/0P<). در گروه تجربی کاهش معنا‌دار هورمون آنتی‌مولرین (016/0=P) و تستوسترون تام (000/0=P) مشاهده شد. همچنین وزن، BMI، WC، WHR (000/0=P)، فشار خون سیستولی (003/0=P)، گلوکز خون ناشتا (019/0=P)، TG (000/0=P) و LDL (035/0=P) کاهش معنا‌دار و HDL (002/0=P) افزایش معنا‌داری یافت. بنابراین، پیشنهاد می‌شود این‌گونه مداخلات پیش از شروع یا همزمان با درمان پزشکی، برای زنان نابارور دارای اضافه وزن و چاق مبتلا به PCOS تجویز شود.
کلیدواژه‌ها
عنوان مقاله [English]
The Effect of three Months of Unsupervised Aerobic Exercise and Low-Calorie Diet on Hormonal, Metabolic and Anthropometric Parameters of Overweight and Obese Infertile Women with Polycystic Ovary Syndrome
نویسندگان [English]
- Zahra Mosadegh Neishabouri 1
- Farhad Rahmani nia 2
- Ashraf Moini 3
- Azadeh Mottaghi 4
1 PhD Candidate Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Guilan University, Rasht, Iran,
2 Professor, Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, Guilan University, Rasht, Iran,
3 Professor, Department of Obstetrics and Gynecology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
4 Assistant Professor, Department of Nutritional Sciences, Endocrinology and Metabolism Research Institute, Iran University of Medical Sciences, Tehran, Iran
چکیده [English]
The aim of this study was to investigate the effect of three months of lifestyle interventions including unsupervised moderate intensity aerobic exercise and low-calorie diet on hormonal, metabolic and anthropometric parameters in overweight and obese infertile women with polycystic ovary syndrome (PCOS). The method of this study was experimental with pretest-posttest design and applied approach. Among infertile women with PCOS referred to Arash Hospital in Tehran, 20 women (age 27.9±2.5 years, weight 81.36±8.05 kg and body mass index 30.27±1.97 kg/m2) were selected as the statistical sample and randomly were divided into two experimental (n=10) and control (n=10) groups. Exercise program and diet were prescribed based on the demographic characteristics of the experimental group. Hormonal, metabolic and anthropometric parameters of the subjects were measured before and after three months.Intragroup comparison was performed with paired sample t-test and intergroup comparison with ANKOVA test in spss software (P<0.05). In the experimental group, a significant decrease in antimullerian hormone (P=0.016) and total testosterone (P=0.000) was observed. Also, weight, BMI, WC, WHR (P=0.000), systolic blood pressure (P=0.003), fasting blood glucose (P=0.019), TG (P=0.000) and LDL (P=0.035) significantly decreased and HDL (P=0.002) significantly increased. Therefore, it is recommended that this type of interventions be prescribed before or simultaneously with medical treatment for overweight and obese infertile women with PCOS.
کلیدواژه‌ها [English]
- Aerobic exercise
- Antimullerian hormone
- Diet
- Hyperandrogenism
- Ovarian reserve
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