نوع مقاله : مقاله پژوهشی Released under CC BY-NC 4.0 license I Open Access I
نویسندگان
1 . دانشجوی کارشناسی ارشد فیزیولوژی ورزشی محض دانشگاه حکیم سبزواری، سبزوار، ایران
2 استادیار گروه فیزیولوژی ورزشی دانشگاه حکیم سبزواری، سبزوار، ایران
3 دانشیار گروه فیزیولوژی ورزشی دانشگاه حکیم سبزواری، سبزوار، ایران
چکیده
هدف: متخصصین سلامتی به نقش مؤثر تمرینات ورزشی بر بهبود سطح سلامت افراد دارایMS اعتقاد دارند. تحقیق حاضر به بررسی تغییرات اینترلوکین 4و17 سرمی و هم‌چنین تغییرات قدرت عضلانی به دنبال 8 هفته تمرینات منظم مقاومتی پرداخت.
روش تحقیق: مطالعه حاضر از نوع کاربردی با طرح پیش و پس‌آزمون بود. 22 نفر از زنان مبتلا به مالتیپل اسکلروزیس در دامنه‌ی سنی 25تا40 سال و با درجه‌ی ناتوانی (EDSS=4) به صورت هدفمند در دو گروه تجربی و کنترل قرار گرفتند. گروه تمرینی 8 هفته، 3 جلسه با شدت 45تا60 درصد یک تکرار بیشینه، تمرینات را انجام دادند و گروه کنترل اما در هیچ فعالیت منظم بدنی شرکت نکردند. قبل و بعد از دوره‌ی تمرینی آزمون‌های تن‌سنجی، قدرت بالاتنه و پایین‌تنه و نمونه‌گیری خون برای سنجش مقادیر اینترلوکین 17و4 انجام گرفت. برای تعیین توزیع طبیعی داده‌ها از آزمون اسمیرنف-کولموگرف و تحلیل واریانس یک‌طرفه برای تفاوت احتمالی در گروه‌ها و آزمون تی زوجی جهت بررسی تغییرات درون‌گروهی استفاده شد. سطح معناداری P≤0/05 در نظر گرفته شد و محاسبات در نرم‌افزار SPSS نسخه‌ی 18 انجام شد.
نتایج: تحلیل آماری نشان داد قدرت آزمودنی‌ها نسبت به گروه کنترل افزایش معناداری داشت (P=0/001). اینترلوکین 4 نیز نسبت به گروه کنترل افزایش معناداری نشان داد (P=0/002) اما اینترلوکین 17 بین دو گروه تفاوتی نداشت.
به نظر می‌رسد زنان مبتلا به مولتیپل اسکلروزیس برای بهبود کارایی سیستم ایمنی و ارتقای سطح قدرت خود بتوانند از تمرینات منظم مقاومتی با شدت متوسط بهره ببرند.
کلیدواژه‌ها
عنوان مقاله [English]
The Effect of resistance Training on Changes in some Cytokines and Muscle Strength in Women with Multiple Sclerosis
نویسندگان [English]
- Mahbobe Shahidi Rad 1
- Roya Askari 2
- Seyyed Alireza Hosseini Kakhk 3
1 MSc Student of Exercise Physiology, Hakim Sabzevari University, Sabzevar, Iran
2 Assistant Professor, Department of Exercise Physiology, Hakim Sabzevari University, Sabzevar, Iran
3 Associate Professor, Department of Exercise Physiology, Hakim Sabzevari University, Sabzevar, Iran
چکیده [English]
Purpose: Health professionals believe in the effective role of exercise training on improving the health of MS patients. The present study to investigate changes in serum levels IL4 and 17, as well as muscle strength changes after 8 weeks of regular resistance training. Methodology: The present study was a applied and pre-post design. Twenty-two women with multiple sclerosis in the range of 25 to 40 years old and with disability (EDSS = 4) were randomly assigned into experimental and control groups. 8-week training sessions, 3 sessions with 45-60% intensity, one repetition, performed exercises, and the control group did not participate in any regular physical activity. Before and after training, anthropometric tests, upper and lower strength and blood sampling were used to measure the levels of Interleukin 17 and 4. To determine the normal distribution of data, the Smirnov-Kolmogorov test and one-way variance analysis were used for the possible difference in the groups and the paired t-test was used to examine the intra-group changes. The significance level was considered to be P≤0 / 05 and the calculations were performed using SPSS version 18. Results: The statistical analysis showed that the subjects' strength was significantly higher than the control group (P = 0.001). Interleukin 4 showed a significant increase compared to the control group (P = 0.002), but interleukin 17 did not differ between the two groups. Women with multiple sclerosis seem to be able to use regular moderate-intensity exercise
کلیدواژه‌ها [English]
- Interleukin 17 and 4
- resistance exercises
- women with MS
- muscle strength
376 علوم زیستی ورزشی، دورة 11 ، شمارة 4، زمستان 1398
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