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تأثیر یک دوره تمرین هوازی بر میزان رزیستین، هموگلوبین گلیکوزیله، شاخص مقاومت به انسولین و برخی ریسک فاکتورهای قلبی- عروقی در زنان چاق دیابتی نوع 2

نوع مقاله : مقاله پژوهشی Released under CC BY-NC 4.0 license I Open Access I

نویسندگان

1 مربی، دانشکدۀ علوم تربیتی و روانشناسی، دانشگاه محقق اردبیلی، اردبیل، ایران

2 دانشیار، دانشکدۀ تربیت بدنی و علوم ورزشی، دانشگاه تهران، تهران، ایران

3 دانشجوی کارشناس ارشد، دانشکدۀ تربیت بدنی و علوم ورزشی، دانشگاه تهران، تهران، ایران

4 دانشجوی دکتری، دانشکدۀ علوم تربیتی و روانشناسی، دانشگاه محقق اردبیلی، اردبیل، ایران

5 دانشجوی کارشناس ارشد، دانشکدۀ تربیت بدنی و علوم ورزشی، دانشگاه خوارزمی، تهران، ایران

چکیده

هدف از این تحقیق بررسی اثر هشت هفته تمرین هوازی بر میزان رزیستین، هموگلوبین گلیکوزیله، شاخص مقاومت به انسولین و برخی ریسک فاکتورهای قلبی- عروقی در زنان چاق دیابتی نوع دو بود. به این منظور 22 زن غیرفعال چاق مبتلا به دیابت نوع دو در کرمانشاه، با میانگین سن 33/2±95/44 سال، وزن 82/5±88/78 کیلوگرم، قد 45/5±11/161 سانتی‌متر به‌طور تصادفی به دو گروه تجربی و کنترل (هر گروه 11 نفر) تقسیم شدند. گروه تجربی به مدت هشت هفته (سه جلسه در هفته، هر جلسه 60 دقیقه) تمرینات هوازی را با شدت 60 تا 80 درصد ضربان قلب بیشینه انجام دادند. دو روز قبل و بعد از مداخله نمونه‌گیری انجام گرفت. از آزمون تی مستقل برای مقایسۀ تفاوت بین‌گروهی و از تی‌همبسته برای مقایسۀ نتایج درون‌گروهی استفاده شد. پس از مداخلۀ متغیرهای وزن، درصد چربی بدن، انسولین، HbA1c، hs-CRP، LDL-C (05/0P=) گلوکز خون ناشتا (032/0P=)، مقاومت به انسولین، رزیستین (04/0P=)، کلسترول (028/0P=) و TG (014/0P=) در گروه تجربی در مقایسه با گروه کنترل به‌صورت معنا‌داری کاهش یافت. میزان HDL-C و BMI بین دو گروه اختلاف معنا‌داری نداشت. متغیرهای وزن (02/0P=)، درصد چربی (01/0P=)، گلوکز (004/0P=)، انسولین (031/0P=)، رزیستین (024/0P=)، TG (039/0P=)، BMI، HbA1c، hs-CRP، LDL-C، (05/0P=)، مقاومت به انسولین و کلسترول (045/0P=)، در پس‌آزمون نسبت به وضعیت پایه در گروه تجربی کاهش معنا‌داری یافتند. با بهبود مقاومت به انسولین و کاهش شاخص‌های التهابی و هموگلوبین گلیکوزیله خطر بالقوۀ ابتلا به بیماری‌ها و عوارض قلبی و دیابت کاهش‌ یافت و فعالیت ورزشی منظم هوازی می‌تواند در کنترل عوارض این بیماری مؤثر باشد.

کلیدواژه‌ها

عنوان مقاله [English]

The Effect of Aerobic Exercise on Resistin, Glycated Hemoglobin, Indicator of Insulin Resistance and Some Cardiovascular Risk Factors in Obese Women with Type 2 Diabetes

نویسندگان [English]

  • Aidin Valizadeh 1
  • Ali Akbarnejad 2
  • Morteza Yare 3
  • Ali Rajabi 4
  • Edris Bavardi-Moghadam 5

1 Instructor, Faculty of Educational Sciences and Psychology, Mohaghegh Ardabali University, Ardabal, Iran

2 Associate Professor, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran

3 MSc Student, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran

4 PhD Student, Faculty of Educational Sciences and Psychology, Mohaghegh Ardabali University, Ardabal, Iran

5 MSc Student, Faculty of Physical Education and Sport Sciences, Kharazmi University, Tehran, Iran

چکیده [English]

The aim of this study was to determine the effect of 8 weeks of aerobic exercise on resistin, glycated hemoglobin, indicator of insulin resistance and some cardiovascular risk factors in obese women with type 2 diabetes. 22 obese sedentary women with type 2 diabetes in Kermanshah (mean age 44.95±2.33 yrs, weight 78.88±0.82 kg, height 161.11±5.45 cm) were randomly divided into 2 groups (each group 11 subjects): experimental and control. The experimental group performed aerobic exercises for 8 weeks (3 sessions per week, each session 60 minutes) with 60-80% of maximum heart rate. Blood samples were collected 2 days before and after the intervention. Independent t test was used to compare the intergroup differences and dependent t test was used to compare the intragroup results. After the intervention, weight, body fat percent, insulin, HbA1c, hc-CRP, LDL-C (P=0.05), fasting blood glucose (P=0.032), insulin resistance, resistin (P=0.04), cholesterol (P=0.028) and TG (P=0.014) significantly decreased in the experimental group compared to the control group. HDL-C and BMI levels had no significant differences between the groups. Weight (P=0.02), fat percent (P=0.01), glucose (P=0.004), insulin (P=0.031), resistin (P=0.024), TG (P=0.039), BMI, HbA1c, hc-CRP, LDL-C (P=0.05), insulin resistance and cholesterol (P=0.045) significantly decreased in the experimental group in the posttest compared with the baseline. The improved insulin resistance and decreased inflammatory markers and glycated hemoglobin reduce the potential risk of cardiac diseases and complications and diabetes and regular aerobic exercise can influence controlling the complications of this disease.

کلیدواژه‌ها [English]

  • aerobic exercise
  • HbA1c
  • hs-CRP
  • insulin resistance
  • obese female patients
  • resistin
  • type 2 diabetes
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نشریه علوم زیستی ورزشی
دوره 10، شماره 3
آذر 1397
صفحه 263-282
فایل ها
سابقه مقاله
  • تاریخ دریافت: 30 فروردین 1395
  • تاریخ بازنگری: 11 دی 1397
  • تاریخ پذیرش: 21 شهریور 1395
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