بررسی تغییرات IL-15، CRP و آیریزین سرمی در فواصل استراحتی مختلف پس از یک جلسه فعالیت مقاومتی در سالمندان

نوع مقاله : مقاله پژوهشی

نویسندگان

دانشجوی دکتری فیزیولوژی ورزش، گرایش بیوشیمی و متابولیسم ورزشی، دانشکدۀ علوم ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران

چکیده

 
پژوهش حاضر با هدف بررسی تغییرات IL-15، CRP و آیریزین سرمی پس از یک جلسه فعالیت مقاومتی در سالمندان و در فواصل مختلف پس از فعالیت و همچنین با نگاه امکان تغییر وضعیت عضلات و بهبود سارکوپنیا انجام گرفت. 15 سالمند (میانگین سنی 5/4±32/63 سال، قد33/2±61/168سانتی‌متر و وزن 2/4±5/78 کیلوگرم) داوطلبانه در این پژوهش شرکت کردند. آزمودنی‌ها به‌مدت 45 دقیقه و در سه دورۀ هشت‌تکراری با شدت 80 درصد 1RM فعالیت با وزنه را انجام دادند. فاصلۀ استراحتی بین دوره‌های هر فعالیت دو دقیقه و فاصلۀ بین فعالیت‌ها سه دقیقه بود. تحلیل آماری داده‌ها با کمک آزمون آماری تحلیل واریانس یکطرفه و آزمون تعقیبی LSD صورت گرفت (05/0P<). یافته‌ها نشان داد که سطوح IL-15 و آیریزین بلافاصله پس از جلسۀ آزمون افزایش معناداری دارد و 24 ساعت پس از جلسۀ آزمون نیز CRP و آیریزین به‌طور معناداری افزایش می‌یابد (05/0P<). 72 ساعت پس از زمان آزمون، فاکتورهای التهابی نسبت به پیش از فعالت افزایش معناداری نشان دادند (05/0P<)؛ بنابراین یک جلسه فعالیت مقاومتی می‌تواند سبب بالا رفتن سطوح برخی از این فاکتورها در سالمندان شود که ممکن است به‌عنوان عاملی تأثیرگذار در بهبود عملکرد عضلانی و به‌ویژه کنترل سارکوپنیا در این افراد عمل کند.

کلیدواژه‌ها


عنوان مقاله [English]

An Examination of the Changes in IL-15, CRP and Serum Irisin in Different Rest Intervals after a Session of Resistance Activity in the Elderly

نویسندگان [English]

  • Ehsan Asghari
  • Zahra Mirzendedel
Ph.D. Student of Exercise Physiology-Sport Biochemistry and Metabolism, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran
چکیده [English]

 
The aim of this study was to evaluate changes of IL-15, CRP and serum irisin after one session of resistance activity in the elderly at different intervals with a view on the possibility of changing the muscles and improving sarcopenia. 15 elderly (mean age 63.32 ± 4.5 years, height 168.61 ± 2.33 cm and weight 78.5 ± 4.2 kg) voluntarily participated in this study. The subjects performed weight training for 45 minutes in 3 sets of 8 repetitions at 80% 1RM intensity with 2- minute rest intervals and 3-minute intervals. For statistical analysis of data, one-way ANOVA and LSD post hoc test were used (P<0.05). The findings showed that levels of IL-15 and irisin significantly increased immediately after the test and levels of CRP and irisin significantly increased 24 hours after the test (P<0.05). Inflammatory factors showed a significant increase 72 hours after the test compared with the period before the activity (P<0.05). So, a session of resistance activity can elevate the levels of some of these factors in the elderly which may function as a factor which affects the improvement of muscle function and especially the control of sarcopenia in these people.
 

کلیدواژه‌ها [English]

  • Elderly
  • inflammatory factors
  • Irisin
  • strength exercis
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