تأثیر تمرین مقاومتی فزاینده بر سیستاتین C و پروتئین واکنش‌پذیر C در مردان والیبالیست

نوع مقاله: مقاله پژوهشی

نویسندگان

1 کارشناس‌ارشد فیزیولوژی ورزشی، گروه فیزیولوژی ورزشی، واحد بروجرد، دانشگاه آزاد اسلامی، بروجرد، ایران

2 استادیار فیزیولوژی ورزشی، گروه فیزیولوژی ورزشی، واحد بروجرد، دانشگاه آزاد اسلامی، بروجرد، ایران

3 استادیار فیزیولوژی ورزشی، گروه تربیت بدنی، واحد سنندج، دانشگاه آزاد اسلامی، سنندج، ایران

چکیده

 
التهاب مزمن با خطر ابتلا به بیماری‌های مختلفی مانند اتروسکلروزیس و دیابت مرتبط است. هدف از تحقیق حاضر بررسی تأثیر هشت هفته تمرین مقاومتی بر تغییرات پروتئین واکنش‌پذیر C و سیستاتین C در مردان ورزشکار بود. به همین منظور 20 آزمودنی از والیبالیست‌های شهرستان سنندج داوطلبانه در تحقیق شرکت کردند و به‌صورت تصادفی در دو گروه مقاومتی فزاینده (10n= ) و کنترل (10n= ) قرار گرفتند. تمرینات مقاومتی فزاینده به‌صورت سه جلسه در هفته و به مدت هشت هفته با شدت 70 درصد یک تکرار بیشینه انجام گرفت و در پایان هفتۀ هشتم به 90 درصد یک تکرار بیشینه رسید. نمونه‌گیری از خون پیش و پس از دورۀ تمرینی برای ارزیابی پروتئین واکنش‌پذیر C و سیستاتین C در پلاسما صورت گرفت. نتایج نشان داد که در تعامل زمان در گروه تفاوت معناداری در سیستاتین C وجود داشت (047/0P=). با وجود این اثر زمان و نیز اثر زمان در گروه در CRP معنادار نبود (05/0P>). نتیجه گرفته می‌شود که هشت هفته تمرین مقاومتی فزاینده می‌تواند موجب کاهش سیستاتین C به‌عنوان یک شاخص التهابی جدید شود. با وجود این چنین پروتکلی تأثیری بر میزان غلظت CRP پایه ندارد. 

کلیدواژه‌ها


عنوان مقاله [English]

The Effect of Progressive Resistance Training on Cystatin C and C Reactive Protein in Male Volleyball Players

نویسندگان [English]

  • dara tarsim 1
  • ahmad hemmatfar 2
  • Kamal Azizbeigi Boukani 3
1 MSc in Exercise Physiology, Department of Exercise Physiology, Borujerd Branch, Islamic Azad University, Borujerd, Iran
2 Assistant Professor in Exercise Physiology, Department of Exercise Physiology, Borujerd Branch, Islamic Azad University, Borujerd, Iran.
3 Assistant Professor in Exercise Physiology, Department of Physical Education, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran
چکیده [English]

 
Chronic inflammation is associated with the development of various diseases such as atherosclerosis and diabetes. The aim of this study was to investigate the effect of 8 weeks of resistance training on changes of C reactive protein (CRP) and cystatin C in male volleyball players. For this purpose, 20 volleyball players voluntarily participated in the study and were divided randomly into progressive resistance training (PRT, n=10) and control (Con, n=10) groups. PRT was conducted for 8 weeks, 3 sessions per week with the intensity of 70% maximal repetition (1RM) and reached 90% 1RM by the 8th week. Blood samples were collected before and after PRT to analyze CRP and cystatin C in the plasma. The results showed that in the interaction of time× group, there was a significant difference in cystatin C (P=0.047). However, the effect of time and the effect of time x group were not significant in CRP (P>0.05). It can be concluded that 8 weeks of progressive resistance training reduced cystatin C as a new inflammatory index. However, this protocol had no effects on basal CRP concentration.

کلیدواژه‌ها [English]

  • cystatin C
  • inflammation
  • resistance training
  1. BarnesJN, Cortez-Cooper MY, Anton MM, and Tanaka H. (2008). The effect of resistance training on systemic inflammatory markers in middle-aged and older adults. The federation proceeding. 22: pp: 753.34.
  2. Braith RW, and Stewart KJ. (2006). Resistance Exercise Training Its Role in the    Preventive  of Cardiovascular Disease. Circulation. 113: pp: 2642-2650.
  3. Brzycki M. (1993). Strength testing: predicting a one – rep max from repetitions-to-fatigue. JOPERD. 64: pp: 88-90.
  4. Clark JC. (2005). Exercise preconditioning ameliorates inflammatory injury in ischemicrats during reperfusion. Acta Neuropathlogica (Ber). 109(3): pp: 237-46.
  5. Culabro P, Willerson JT, Yeh ET. (2003). Inflammatory cytokines stimulated CRP production by human coronary artery smooth muscle cells. Circulation. 108:1930.
  6. Curhan G. (2005). Cystatin C: A Marker of Renal Function or Something More? Clinical chemistry. 51(2): pp: 293-294.
  7. Donges CE, Duffield R, Drinkwater EJ. (2010). Effects of resistance or aerobic exercise training on interleukin-6, C-reactive protein, and body composition. Medicine and science in sports and exercise. 42(2): pp: 304–13.
    1. Fried L, Solomon C, Shlipak M, Seliger S, Stehman-Breen C, Bleyer AJ, et al. (2004). Inflammatory and prothrombotic markers and the progression of renal disease in elderly individuals. Journal of the American Society of Nephrology . 15(12): pp: 3184-91.
    2. Haghighi M. (1385). Effect of endurance and resistance training on inflammatory factors in obese men [dissertation]. Tehran University.
    3. Hammett CJK,  Prapavessis H,  Baldi JC,  Varo N,  Schoenbeck U, Ameratunga R et al. (2006). Effects of exercise training on 5 inflammatory markers associated with cardiovascular risk.  American heart journal. 151(2):367: pp: 7-367.
    4. Heffernan KS, Jae SE, Vieira VJ, Iwamoto GA, Wilund KR, Woods JA et al. (2009). C- reactive protein and cardiac vagal activity following resistance exercise Training in young African-American and white men. American journal of physiology- regulatory integration and comparative. 296: pp: 1098–1105.
    5. Hosaini Kakhak A, Amiri Parsa A, Haghighi T, Askari A, Chmari R, Hedaiati M. (1388). Effect of resistance training on C reactive protein and Cystatine C in obese women. Journal of daneshwar. in Persian. 17(85): pp: 9-18.
    6. Jialal I, Devaraj S, Venugopal SK. (2004). C-reactive protein: risk marker or mediator in atherothrombosis? Hypertension. 44: pp: 6–1.
    7. Ketabipoor SM, Koushkie-Jahromi M, Salesi M, Saboori A. (2014). Effect of eight weeks selected aquatic aerobic on cystatine C and some risk factors in menopausal women. A randomized clinical trial. Journal of Shahrekord University of Medical Sciences. 15(6): pp: 109-116.
      1. Laura K. Stewart; Michael G. Flynn; Wayne W. Campbell et al. (2007). The Influence of Exercise Training on inflammatory Cytokines and C-reactive protein. Science. pp: 387-398.
      2. Levinger I, Goodman C, Peake J, Garnham A, Hare DL, Jerums G, and et al. (2009). Inflammation, hepatic enzymes and resistance training in individuals with metabolic risk factors. Diabetic Medicine. 26: pp: 220-7.
      3. McManus D, Shlipak M, Joachim H, Ali S, and Whooley MA. (2007). Association of Cystatin C with Poor Exercise Capacity and Heart Rate Recovery: Data from the Heart and Soul Study. American journal of kidney diseases. 49(3): pp: 365-372.
      4. Muntner P, Winston J, Uribarri J, Mann D, Fox CS. (2008). Over Weight, Obesity, and Elevated Serum Cystatine C Levels in Adults in the United States. American journal of medicine. 121: pp: 341-348.
      5. Pechter Ü, Maaroos J, Mesikepp S, Veraksits A, and Ots M. (2003). Regular low- intensity aquatic exercise improves cardio-respiratoryfunctional capacity and reduces proteinuria in chronic renal failure patients. Nephrology Dialysis Transplantation 18: pp: 624-625.
      6. Rector RS, Smith BK, Sun GY Liu Y, Thomas TR. (2004). C-Reactive Protein and Secretary phospholipase A2 are Unaffected by Exercise or Omega-3 fatty
Acid Supplementation. Medicine and science in sports and exercise. pp: 36:326.