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اثر حاد و مزمن فعالیت رکاب زدن زیربیشینه همراه با محدودیت جریان خون برBDNF و TNFα سرمی مردان فعال

نوع مقاله : مقاله پژوهشی Released under CC BY-NC 4.0 license I Open Access I

نویسندگان

1 دانشجوی دکتری فیزیولوژی ورزشی، دانشکدۀ تربیت بدنی و علوم ورزشی، دانشگاه تهران، تهران، ایران

2 دانشیار فیزیولوژی ورزشی، دانشکدۀ تربیت بدنی و علوم ورزشی، دانشگاه خوارزمی، تهران، ایران

3 کارشناس‌ارشد زیست‌شناسی، دانشکدۀ علوم زیستی، دانشگاه خوارزمی، تهران، ایران

چکیده

 این مطالعه به‌منظور تعیین اثر حاد و مزمن فعالیت رکاب زدن زیربیشینه همراه با محدودیت جریان خون بر سطح سرمی BDNF، TNF-α و نسبت BDNF به TNF-αدر مردان فعال انجام گرفت. 24 نفر از دانشجویان تربیت بدنی دانشگاه خوارزمی داوطلب شرکت در پژوهش شدند و به سه گروه رکاب زدن همراه با انسداد عروق پا (8n=)، رکاب زدن بدون انسداد (8n=) و کنترل (8n=) تقسیم شدند. آزمودنی‌های گروه تمرین با انسداد و تمرین بدون انسداد به مدت 3 هفته، هر هفته 3 جلسه و در مجموع 9 جلسه تمرین کردند. هر جلسۀ تمرین شامل 3 وهلۀ سه‌دقیقه‌ای رکاب زدن با شدت50 درصد Wmax بود و بین هر وهله 45-30 ثانیه استراحت وجود داشت (میزان فشار روی ران در گروه انسداد،170-140 میلی‌متر جیوه بود). برای تجزیه‌وتحلیل داده‌ها، از آزمون­های تحلیل واریانس یکسویه، t مستقل و t وابسته استفاده شد. نتایج نشان داد انسداد عروق پا هنگام فعالیت زیربیشینۀ رکاب زدن بر پاسخ سطوح BDNF(290/0 P=)، TNF-α(338/ 0P=) و نسبت BDNF به TNF-α(384/0 P=) در مقایسه با گروه­ بدون انسداد تفاوت معناداری ندارد. از طرفی به‌هنگام سازگاری، در سطوح BDNF(254/0 P=)، TNF-α(338/ 0P=) و نسبت BDNF به TNF-α(384/0 P=) بین گروه­های انسداد، بدون انسداد و کنترل نیز تفاوت معناداری مشاهده نشد. نتایج نشان داد که محدودیت جریان خون موضعی اثر مثبت یا منفی بر میزان BDNF، TNF-αو نسبت آنها ندارد.

کلیدواژه‌ها

عنوان مقاله [English]

The Chronic and Acute Effect of Submaximal Pedaling Activity along with Blood Flow Restriction on Serum BDNF and TNF-α in Active Men

نویسندگان [English]

  • Saeed Rahmati 1
  • Hamid Rajabi 2
  • Latifeh Karimzadeh 3

1 corresponding authur

2 Researcher

3 Researcher

چکیده [English]

This study aimed at determining the chronic and acute effect of submaximal pedaling activity along with blood flow restriction on serum BDNF, TNF-α and BDNF/TNF-α ratio in active men. 24 physical education students at Kharazmi University volunteered for the study. They were divided into three groups: pedaling with lower extremity vascular occlusion (n=8), pedaling without occlusion (n=8), and control (n=8). Subjects in the occlusion and non-occlusion groups exercised for 3 weeks, 3 sessions per week (9 sessions totally). Each session included three 3-min. phases of pedaling at 50% of maximum power (Wmax) with 30–45 s rest interval between each two phases. The pressure on the thigh in the occlusion group was 140–170 mmHg. To analyze the data, one-way analysis of variance and independent and dependent t tests were used. Results showed that leg vessels occlusion during submaximal pedaling had no significant differences on response of BDNF (P=0.290)، TNF-α (P=0.338) and their ratio (P=0.384) compared with the non-occlusion group. In addition, in the compatibility phase, there were no significant differences in BDNF (P=0.254)، TNF-α (P=0.338) and their ratio (P=0.384) among occlusion, non-occlusion and control groups. Results showed that local blood flow restriction had no positive or negative effects on the amounts of BDNF, TNF-α and their ratio.

کلیدواژه‌ها [English]

  • blood flow restriction (BFR)
  • brain derived neurotrophic factor (BDNF)
  • occlusion training
  • tumor necrosis factor alpha (TNF-α)
مراجع
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نشریه علوم زیستی ورزشی
دوره 8، شماره 2
شهریور 1395
صفحه 247-262
فایل ها
سابقه مقاله
  • تاریخ دریافت: 30 آذر 1393
  • تاریخ بازنگری: 02 اردیبهشت 1394
  • تاریخ پذیرش: 02 اردیبهشت 1394
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