اثر ده هفته تمرین هوازی بر میزان فیلتراسیون گلومرولی و سطوح اوره، کراتینین و اسید اوریک خون مردان مسن دیابتی نوع دو

نوع مقاله: مقاله پژوهشی

نویسندگان

1 دانشیار، عضو هیأت علمی دانشکدۀ تربیت بدنی و علوم ورزشی دانشگاه بوعلی سینا، همدان، ایران

2 دانشجوی دکتری فیزیولوژی ورزش، پژوهشکدۀ طب ورزشی، پژوهشگاه تربیت بدنی و علوم ورزشی، تهران، ایران

چکیده

چکیده
هدف از این پژوهش بررسی اثر تمرینات هوازی بر میزان فیلتراسیون گلومرولی و سطوح سرمی فاکتورهای بیوشیمیایی اوره، کراتینین و اسید اوریک در مردان مبتلا به دیابت نوع دو است. نمونه‌ها 23 بیمار دیابتی نوع دوم 60–40 ساله بودند که به دو گروه تجربی (13N=) و کنترل (10N=) تقسیم شدند. گروه تجربی به مدت ده هفته برنامۀ هوازی (دو تا سه جلسه در هفته و هر جلسه 90-60 دقیقه، با شدت 85- 55 درصد ضربان قلب بیشینه) انجام دادند؛ و گروه کنترل به فعالیت‌های روزمرۀ خود پرداختند. از آزمودنی‌ها در دو نوبت پیش و پس‌آزمون نمونه‌های خونی گرفته شد؛ متغیرها با استفاده از دستگاه‌های بیوشیمیایی اتوآنالایزر اندازه‌گیری شدند. به‌منظور تجزیه‌وتحلیل داده‌ها از آزمون تی همبسته استفاده شد. یافته‌ها نشان داد میزان فیلتراسیون گلومرولی (028/0P=)، سطح اوره (013/0P=) و کراتینین (027/0P=) خون در گروه تجربی کاهش یافت. درحالی‌که میزان همین فاکتورها در گروه کنترل تغییر شایان توجهی نداشت. این پژوهش نشان داد ده هفته تمرین هوازی موجب بهبود سطح اوره و کراتینین خون شد، درحالی‌که تأثیر معنا‌داری بر مقدار اسید اوریک خون نداشت؛ به‌عبارت ‌دیگر، این ورزش‌ها می‌تواند به بهبود عوارض کلیوی در این بیماران کمک کند.
 

کلیدواژه‌ها


عنوان مقاله [English]

The Effect of 10 Weeks of Aerobic Exercises on Glomerular Filtration Rate (GFR) and Urea, Creatine and Uric Acid Levels in Elderly Men with Type 2 Diabetes

نویسندگان [English]

  • mohammad ali samavati sharif 1
  • Hogatolah seiavoshi 2
1 Associate Professor of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Bu-Ali Sina University, Hamadan, Iran
2 PhD Student of Exercise Physiology, Sports Medicine Research Center, Sport Sciences Research Institute of IRAN (SSRI), Tehran, Iran
چکیده [English]

The aim of this study was to determine the effect of aerobic exercises on glomerular filtration rate (GFR) and serum levels of biochemical factors of urea (BUN), creatine (Cr) and uric acid (UAc) in type 2 diabetic men. The sample consisted of 23 type 2 diabetic patients with age range of 45-60 years old who were divided into two groups of experimental (N=13) and control (N=10). Experimental group performed aerobic exercises for 10 weeks (2-3 sessions per week, each session 60-90 minutes with intensity of 55-85% of maximum heart rate) whereas control group had their daily activity. Blood samples were obtained at baseline and after the intervention phase. The variables were measured using autoanalyzer biochemical sets. To analyze the data, paired sample t test was used. Results showed that glomerular filtration rate (GFR) (P=0.028), urea (BUN) (P=0.013), and creatine (Cr) (P=0.027) reduced in experimental group whereas these variables did not change drastically in control group. These results suggested that 10 weeks of aerobic exercises improve blood urea and creatine while these exercises did not affect blood uric acid (UAc). In other words, these exercises can contribute to renal improvement in these patients.
 
 

کلیدواژه‌ها [English]

  • creatine
  • endurance activity
  • glomerular filtration
  • type 2 diabetes
  • Urea
  • uric acid
 

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