تاثیر دوازده هفته تمرینات ترکیبی همراه با کاتسو بر برخی فاکتورهای رشدی زنان جوان

جعفری, لیلا; سلطانی, محمود; حسین آبادی, محمد رضا; برجسته یزدی, آمنه

doi:10.22059/jsb.2024.364778.1607

نوع مقاله : مقاله پژوهشی Released under CC BY-NC 4.0 license I Open Access I

نویسندگان

¹ دانشجوی دکتری فیزیولوژی ورزشی، گروه تربیتبدنی و علوم ورزشی، واحد نیشابور، دانشگاه آزاد اسلامی، نیشابور، ایران.

² استادیار، گروه تربیت بدنی و علوم ورزشی، واحد مشهد، دانشگاه آزاد اسلامی، مشهد، ایران.

³ استادیار، گروه تربیت بدنی و علوم ورزشی، واحد نیشابور، دانشگاه آزاد اسلامی، نیشابور، ایران.

10.22059/jsb.2024.364778.1607

چکیده

مقدمه: امروزه تمرینات ورزشی برای بهبود بسیاری از افراد جامعه مطلوب شناخته است. موضوع این پژوهش تأثیر 12 هفته تمرینات ترکیبی همراه با کاتسو بر برخی فاکتورهای رشدی زنان جوان بود.

روش پژوهش: جامعۀ آماری این پژوهش زنان جوان غیرفعال شهر مشهد بودند. از بین آنها 45 نفر از افراد غیرفعال به صورت تصادفی به سه گروه تمرین ترکیبی+ کاتسو (15 نفر)، گروه تمرین ترکیبی + بدون کاتسو(15 نفر) و گروه کنترل (15 نفر) تقسیم شدند. روش کار حاضر از نوع نیمه تجربی است و با طرح پیشآزمون-پسآزمون. گروه تمرین ترکیبی هفتهای سه جلسه تمرین مقاومتی و هوازی انجام دادند به این صورت است که این تمرینات در روزهای متوالی صورت گرفت. گروه تمرین ترکیبی با کاتسو، تمرین مقاومتی را با بستن کاف و شدت تمرین %20 RM1 در ابتدای تمرین و تمرین هوازی را با %45 HRmax و گروه تمرین ترکیبی بدون کاتسو، تمرین مقاومتی با %80 RM1و تمرین هوازی را با %45 HRmax و گروه تمرین ترکیبی با کاتسو و گروه تمرین ترکیبی بدون کاتسو، فقط تمرینات ترکیبی را انجام دادند. داده ها با استفاده از «تی همبسته»، «آزمون تحلیل واریانس یکطرفه» و «آزمون تعقیبی بونفرونی»؛ در سطح معناداری 0/05≥P با استفاده از نرمافزار SPSS نسخۀ 22 تحلیل شدند.

یافته ها: نتایج آماری نشان داد 12 هفته تمرینات ترکیبی با کاتسو و بدون کاتسو، سبب افزایش سطوح -1IGF، فولیستاتین و کاهش مایوستاتین در زنان جوان شد (0/05=P)

نتیجه گیری: بنابر نتایج این پژوهش، تمرینات ترکیبی همراه با کاتسو در افزایش فاکتورهای رشدی زنان جوان مطلوب است و در ارتقای وضعیت سلامتی آنها تأثیرگذار است

کلیدواژه‌ها

موضوعات

فیزیولوژی ورزشی

عنوان مقاله [English]

The Effect Of 12 Weeks Combined Exercises With Katsu On Some Growth Factors Of Young Women

نویسندگان [English]

Leyla Jafari ¹
Mahmoud Soltani ²
Mohammad Reza Hoseinabadi ³
Amene Barjaste Yazdi ³

¹ Phd Student of sports physiology, department of physical education and sports science Neyshabur Branch, Islamic Azad University, Neyshabur, Iran

² Assistant Professor,. Department of physical education and sports science. Mashhad Branch, Islamic Azad University, Mashhad, Iran.

³ Assistant Professor, Department of physical education and sports science. Neyshabur Branch, Islamic Azad University, Neyshabur, Iran

چکیده [English]

Introduction: sports exercises are known to be desirable for the improvement of many people in society. The subject of this research was the effect of 12 weeks of combined exercises with katsu on some growth factors in young women.

Method: The statistical population of this research was inactive young women from Mashhad City. Among them, 45 inactive people were randomly assigned into three combined training + katsu (15 people), combined training + without katsu (15 people), and control (15 people) groups. The current research was quasi-experimental with a pre-test and post-test design. The combined training group performed three consecutive sessions of resistance and aerobic exercises per week. The combined training group with katsu performed resistance exercises by implementing a cuff with the intensity of 20% of one maximum repetition (1RM) at the beginning of the training and aerobic training with 45% of the maximum heart rate (HRmax). the combined training group without katsu, performed resistance training with 80% of 1RM and aerobic training with 45% of HRmax. the combined training group with katsu and the combined training group without katsu only performed the combined exercises. The data were analyzed using T-test, one-way analysis of variance test, and Bonferroni's post hoc test at a significance level of P≤0.05 via SPSS software version 21.
Results: Statistical results showed that twelve weeks of combined training with and without katsu increased the levels of IGF-1, follistatin and decreased myostatin in young women (P=0.05).

Conclusion: According to the results of this research, combined exercises with katsu are desirable in increasing the growth factors of young women and are effective in improving their health status.

کلیدواژه‌ها [English]

Combined Training
Blood flow Restriction
growth Factors
Young Women

مراجع

[1]. Arntz F, Markov A, Behm DG, Behrens M, Negra Y, Nakamura M, et al. Chronic Effects of Static Stretching Exercises on Muscle Strength and Power in Healthy Individuals Across the Lifespan: A Systematic Review with Multi-level Meta-analysis. Sports Medicine. 2023:1-23. DOI: 10.1007/s40279-022-01806-9

[2]. Guo Y, Zhang K, Geng W, Chen B, Wang D, Wang Z, et al. Evolutionary analysis and functional characterization reveal the role of the insulin-like growth factor system in a diversified selection of chickens (Gallus gallus). Poultry Science. 2023;102(3):102411.DOI:10.1016/j.psj.2022.102411.

[3]. Kartika, RW, Sidharta V, Djuartina T, Rika I, Sartika CR, Timotius KH. Role of myostatin protein in sarcopenia (aging muscle) after conditioned medium umbilical cord mesenchymal stem cells (secretome) therapy: mini-review. Bali Medical Journal. 2023;12(1):7-10. DOI:10.15562/bmj.v12i1.3790

[4]. Lee S-J, Bhasin S, Klickstein L, Krishnan V, Rooks D. Challenges and Future Prospects of Targeting Myostatin/Activin A Signaling to Treat Diseases of Muscle Loss and Metabolic Dysfunction. The Journals of Gerontology: Series A. 2023:glad033.DOI:10.1093/gerona/glad033

[5]. Silva MZC, Vogt BP, Reis NSC, Minicucci FC, Dorna MS, Minicucci MF, et al. Serum myostatin levels are associated with physical function and hospitalization in peritoneal dialysis patients. European Journal of Clinical Nutrition. 2023;77(2):292-4.doi:10.1038/s41430-022-01227-x.

[6]. Hanson AM, Young MH, Harrison BC, Zhou X, Han H, Stodieck LS, et al. Inhibiting myostatin signaling partially mitigates structural and functional adaptations to hindlimb suspension in mice. npj Microgravity. 2023;9(1):2. DOI:10.1038/s41526-022-00233-4.

[7]. Santos HO, Cerqueira HS, Tinsley GM. The Effects of Dietary Supplements, Nutraceutical Agents, and Physical Exercise on Myostatin Levels: Hope or Hype? Metabolites. 2022;12(11):1146. DOI:10.3390/metabo12111146.

[8]. Lee S-J. Quadrupling muscle mass in mice by targeting TGF-ß signaling pathways. PloS one. 2007;2(8):e789.DOI:10.1371/journal.pone.0000789.

[9]. Amani-Shalamzari S, Farhani F, Rajabi H, Abbasi A, Sarikhani A, Paton C, et al. Blood flow restriction during futsal training increases muscle activation and strength. Frontiers in physiology. 2019;10:614. DOI:10.3389/fphys.2019.00614

[10]. Shabkhiz, F, Chubineh, S, Ghafarian Isfahani, A, Yari, M, Response of serum myostatin to a bout of resistance training with and without blood flow restriction in immature male athletes. Physiology and management research in sports. 2016, 9-19 [in Persian].

[11]. Nasr Sh, Nakisa A, Jandaghian S, Kouhi M, Sadeghi E, Varshosaz J. A Systematic Review and Meta-analysis on the Effect of Flavonoids on Insulin-like Growth Factor and Insulin-like Growth Factor Binding Protein and Incidence of Breast Cancer. Current Medicinal Chemistry. 2023. DOI:10.2174/0929867329666220801164740.

[12]. Signorile PG, Viceconte R, Vincenzi B, Baldi A. Differential Expression in Endometriosis Tissue versus Endometrium of the Uterine Adenogenesis Factors PRL-R, GH, IGF1, and IGF2. Critical Reviews™ in Eukaryotic Gene Expression. 2023;33(3).DOI:10.1615/CritRevEukaryotGeneExpr.2022045360.

[13]. Kohama EB, da Silva ASR, Rocha A, Puggina EF, Fornel R, Custódio R, et al. IGF-I and IGFBP-3 are modulated in adolescents during a competitive soccer season. 2023. 10.22271/kheljournal.2023.v10.i1d.2779

[14]. Lopes KG, Bottino DA, Farinatti P, de Souza MdGC, Maranhão PA, de Araujo CMS, et al. Strength training with blood flow restriction–a novel therapeutic approach for older adults with sarcopenia? A case report. Clinical Interventions in Aging. 2019:1461-9. DOI:10.2147/CIA.S206522.

[15]. Torpel A, Brennicke M, Kuck M, Behrendt T, Schega L. Effect of blood flow restriction training in combination with a high-intensity interval training on physical performance. Int J Sport Exerc Med. 2018;10:2469-5718.DOI:10.23937/2469-5718/1510111

[16]. Chen HT, Chung YC, Chen YJ, Ho SY, Wu HJ. Effects of different types of exercise on body composition, muscle strength, and IGF‐1 in the elderly with sarcopenic obesity. Journal of the American Geriatrics Society. 2017;65(4):827-32.DOI:10.1111/jgs.14722.

[17]. Abe T, Yasuda T, Midorikawa T, Sato Y, CF K, Inoue K, et al. Skeletal muscle size and circulating IGF-1 are increased after two weeks of twice-daily "KAATSU" resistance training. International Journal of KAATSU Training Research. 2005;1(1):6-12.DOI:10.3806/IJKTR.1.6.

[18]. Laurentino GC, Loenneke JP, Ugrinowitsch C, Aoki MS, Soares AG, Roschel H, et al. Blood-flow-restriction-training-induced hormonal Response is not Associated with Gains in Muscle Size and Strength. Journal of human kinetics. 2022;83(1):235-43. DOI: 10.2478/hukin-2022-0095.

[19]. EBRAHIMNIA M, HOSSEINI KSA, HAGHIGHI AH. The Effect Of Three Combined Training Methods (Aerobic And Resistance) With And Without Vascular Occlusion On Some Indices Of Hypertrophy In Elderly Women. 2019.1(22): 82-97 [in Persian].

[20]. Behringer M, Behlau D, Montag JC, McCourt ML, Mester J. Low-intensity sprint training with blood flow restriction improves 100-m dash. The Journal of Strength & Conditioning Research. 2017;31(9):2462-72. DOI:10.1519/JSC.0000000000001746.

[21]. Novak S, Madunic J, Shum L, Vucetic M, Wang X, Tanigawa H, et al. PDGF inhibits BMP2-induced bone healing. npj Regenerative Medicine. 2023;8(1):3. DOI: 10.1038/s41536-023-00276-5.

[22]. Seyedi SH, Khajei R, Rashidlamir A, Ramezanpour MR, Mehrzad J. Effect of eight weeks of aerobic-resistance training on stromal cell-derived factor-1 and platelet-derived growth factor level in patients with coronary artery bypass grafting: A clinical trial study. Journal of Gorgan University of Medical Sciences. 2021;23(2):16-23. [in Persian].

[23]. Rahimi M, Ghaforyan S, Asad MR, Abbasi A. The Effect of Exercise with Different Intensity on Platelet-Derived Growth Factor Gene Expression in Visceral and Subcutaneous Adipose Tissue of Rats. Report of Health Care. 2017;3(3):37-45. [in Persian]

[24]. Palmefors H, DuttaRoy S, Rundqvist B, Börjesson M. The effect of physical activity or exercise on key biomarkers in atherosclerosis–a systematic review. Atherosclerosis. 2014;235(1):150-61. DOI:10.1016/j.atherosclerosis.2014.04.026.

[25]. Czarkowska-Paczek B, Zendzian-Piotrowska M, Bartlomiejczyk I, Przybylski J, Gorski J. The influence of physical exercise on the generation of TGF-β1, PDGF-AA, and VEGF-A in adipose tissue. European journal of applied physiology. 2011;111:875-81.DOI: 10.1007/s00421-010-1693-2.

[26]. Barari A, Bashiri J, Sarabandi M. The effect of circuit resistance training combined with ginseng supplementation levels of VEGF and PDGF in inactive females. Medical Journal of Tabriz University of Medical Sciences. 2015;37(5):6-13. [in Persian]

[27]. Da Silva JC, Freitas ED, Aniceto RR, Silva KF, Araújo JP, Bembem MG, et al. Aerobic exercise with blood flow restriction: Energy expenditure, excess post-exercise oxygen consumption, and respiratory exchange ratio. Clinical Physiology and Functional Imaging. 2022;42(4):241-9. DOI:10.1111/cpf.12753.

[28]. Amorim S, Gaspar AP, Degens H, Cendoroglo MS, de Mello Franco FG, Ritti-Dias RM, et al. The effect of a single bout of resistance exercise with blood flow restriction on arterial stiffness in older people with slow gait speed: A pilot randomized study. Journal of Cardiovascular Development and Disease. 2022;9(3):85. DOI:10.3390/jcdd9030085.

[29]. Chen Y, Wang J, Li S, Li Y. Acute effects of low load resistance training with blood flow restriction on serum growth hormone, insulin-like growth factor-1, and testosterone in patients with mild to moderate unilateral knee osteoarthritis. Heliyon. 2022;8(10):e11051.DOI:10.1016/j.heliyon.2022.e11051.

[30]. Zhang T, Wang X, Wang J. Effect of blood flow restriction combined with low-intensity training on the lower limbs muscle strength and function in older adults: A meta-analysis. Experimental Gerontology. 2022:111827.DOI:10.1016/j.exger.2022.111827.

[31]. Chang H, Yao M, Chen B, Qi Y, Zhang J. Effects of Blood Flow Restriction Combined with Low-Intensity Resistance Training on Lower-Limb Muscle Strength and Mass in Post-Middle-Aged Adults: A Systematic Review and Meta-Analysis. International Journal of Environmental Research and Public Health. 2022;19(23):15691.DOI:10.3390/ijerph192315691.

[32]. Lim ZX, Goh J. Effects of blood flow restriction (BFR) with resistance exercise on musculoskeletal health in older adults: a narrative review. European Review of Aging and Physical Activity. 2022;19(1):1-16. DOI:10.1186/s11556-022-00294-0.

[33]. Rezaee Z, Javaheri SAAH, Rashidlamir A, Oral O, Stavropoulos E. Effects of BFR training in serum NRG-1 and IL-6 in overweight postmenopausal women, 2022, 27(4):541-554.

[34]. Vakili J, Amirsasan R, Sanei P. Effects of 4 weeks resistance training with and without blood flow restriction on GH, IGF-1, NO, and Lactate in male rock climbers. Journal of Sport Biosciences. 2022;14(1):33-48.DOI: 10.22059/jsb.2021.323313.1468 [in Persian].

[35]. Jensen AE, Palombo LJ, Niederberger B, Turcotte LP, Kelly KR. Exercise training with blood flow restriction has little effect on muscular strength and does not change IGF-1 in fit military warfighters. Growth Hormone & IGF Research. 2016;27:33-40.DOI:10.1016/j.ghir.2016.02.003.

[36]. Arnarson A, Geirsdottir OG, Ramel A, Jonsson P, Thorsdottir I. Insulin-like growth factor-1 and resistance exercise in community-dwelling old adults. The journal of nutrition, health & aging. 2015;19:856-60. DOI:10.1007/s12603-015-0547-3.

[37]. Manini TM, Yarrow JF, Buford TW, Clark BC, Conover CF, Borst SE. Growth hormone responses to acute resistance exercise with vascular restriction in young and old men. Growth Hormone & IGF Research. 2012;22(5):167-72. DOI:10.1016/j.ghir.2012.05.002.

[38]. Pazokian F, Amani-Shalamzari S, Rajabi H. Effects of functional training with blood occlusion on the irisin, follistatin, and myostatin myokines in elderly men. European Review of Aging and Physical Activity. 2022;19(1):22. Doi:10.1186/s11556-022-00303-2.

[39]. Motahari Rad M, Bijeh N, Attarzadeh Hosseini SR, Raouf Saeb A. The effect of two concurrent exercise modalities on serum concentrations of FGF21, irisin, follistatin, and myostatin in men with type 2 diabetes mellitus. Archives of Physiology and Biochemistry. 2020:1-10. DOI: 10.1080/13813455.2020.1829649.

[40]. Bagheri R, Rashidlamir A, Attarzadeh Hosseini SR. Effect of resistance training with blood flow restriction on follistatin to myostatin ratio, body composition, and anaerobic power of trained volleyball players. Medical Laboratory Journal. 2018;12(6):28-33. DOI:10.29252/mlj.12.6.28 [in Persian].

[41]. Santos A, Neves Jr M, Gualano B, Laurentino G, Lancha Jr A, Ugrinowitsch C, et al. Blood flow restricted resistance training attenuates myostatin gene expression in a patient with inclusion body myositis. Biology of sport. 2014;31(2):121-4. DOI:10.5604/20831862.1097479.

[42]. Goharshad Mohammadi Gonbad*, Amin Farzaneh Hessari, Hajar Abbaszadeh. 2018. Comparison of the effect of a period of resistance training with blood flow restriction and traditional resistance training on serum myostatin levels, muscle volume and some physiological indicators in middle-aged women: a clinical trial. Rafsanjan University of Medical Sciences. 31-42.DOI:20.1001.1.17353165.1398.18.1.1.7 [in Persian].

[43]. Khoubi M, Habibi A, Ghanbarzadeh M, Shakerian S, Mirzaii B. Acute interval waking with blood flow restriction could not increase ERK, p38 and decrease myostatin. The Journal of Sports Medicine and Physical Fitness. 2020;60(1):32-6. DOI:10.23736/S0022-4707.18.09200-9.

[44]. Esmat Rashidi, Seyed Alireza Hosseini Kakhek, Roya Askari. 2018. The effect of resistance training programs with two different intensities on the serum concentration of myostatin and muscle mass of elderly women. The 3rd National Congress of Sports Science and Health Achievements [in Persian].

[45]. Mohammadi, R, Afrondeh, R, Khaje Landi, M, Mohammadian, M. Investigating the acute effect of resistance training with and without blood flow restriction on indicators related to muscle hypertrophy. Rehabilitation medicine, 2019, 147-155, DOI:10.22037/jrm.2019.112040.2146. [in Persian]

[46]. Soomro A, Khajehei M, Li R, O’Neil K, Zhang D, Gao B, et al. A therapeutic target for CKD: activin A facilitates TGFβ1 profibrotic signaling. Cellular & Molecular Biology Letters. 2023;28(1):10. DOI:10.1186/s11658-023-00424-1.

[47]. Aoki MS, Soares AG, Miyabara EH, Baptista IL, Moriscot AS. Expression of genes related to myostatin signaling during rat skeletal muscle longitudinal growth. Muscle & Nerve: Official Journal of the American Association of Electrodiagnostic Medicine. 2009;40(6):992-9. DOI:10.1002/mus.21426.

[48]. Arabzadeh E, Ghassemi Gil-kalayeh Z, Gholami M, Abed Natanzi H, Ebrahimi S. The effect of 8 weeks of circuit resistance training on serum levels of decorin and IGF-I in sedentary young men. Sport Sciences for Health. 2023:1-7. DOI:10.1007/s11332-022-01035-7.

[49]. Elham Wasadi*\, Farhad Gholami, Elham Mortazavi. 1400. The effect of eight weeks of exercise with different intensities on decorin and TGF-β gene expression in adult male rats. Ilam University of Medical Sciences 2. 86-94. DOI:10.52547/sjimu.29.2.86 [in Persian].

[50]. Elham Wasadi, Farhad Gholami, Elham Mortazavi. 1400. The effect of eight weeks of exercise with different intensities on decorin and TGF-β gene expression in adult male rats. Ilam University of Medical Sciences 2. 86-94.DOI:10.52547/sjimu.29.2.86 [in persian].

[51]. Jalal Shirzad, Asghar Tawfighi, Javad Toloui Azar, Mohammad Hassan Khadim Ansari. 2019. Adaptation of serum irisin, follistatin, and myostatin to eight weeks of resistance, aerobic, and combined training in obese men. Physiology and management research in sports 4. 21-39. [in Persian]

[52]. Jensky NE, Sims JK, Dieli-Conwright CM, Sattler FR, Rice JC, Schroeder ET. Exercise does not influence myostatin and follistatin mRNA expression in young women. Journal of strength and conditioning research/National Strength & Conditioning Association. 2010;24(2):522. DOI:10.1519/JSC.0b013e3181c8664f.

[53]. Hansen J, Brandt C, Nielsen AR, Hojman P, Whitham M, Febbraio MA, et al. Exercise induces a marked increase in plasma follistatin: evidence that follistatin is a contraction-induced hepatokine. Endocrinology. 2011;152(1):164-71.DOI:10.1210/en.2010-0868.

[54]. Renzini A, D’onghia M, Coletti D, Moresi V. Histone deacetylases as modulators of the crosstalk between skeletal muscle and other organs. Frontiers in physiology. 2022:282.DOI:10.3389/fphys.2022.706003.

[55]. Hansen JS, Rutti S, Arous C, Clemmesen JO, Secher NH, Drescher A, et al. Circulating follistatin is liver-derived and regulated bشy the glucagon-to-insulin ratio. The Journal of Clinical Endocrinology & Metabolism. 2016;101(2):550-60.DOI:10.1210/jc.2015-3668.

[56]. Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, et al. A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy. Cell. 2012;151(6):1319-31.DOI: 10.1016/j.cell.2012.10.050.

تاثیر دوازده هفته تمرینات ترکیبی همراه با کاتسو بر برخی فاکتورهای رشدی زنان جوان

مراجع

مراجع

[2]. Guo Y, Zhang K, Geng W, Chen B, Wang D, Wang Z, et al. Evolutionary analysis and functional characterization reveal the role of the insulin-like growth factor system in a diversified selection of chickens (Gallus gallus). Poultry Science. 2023;102(3):102411.DOI:10.1016/j.psj.2022.102411.

[3]. Kartika, RW, Sidharta V, Djuartina T, Rika I, Sartika CR, Timotius KH. Role of myostatin protein in sarcopenia (aging muscle) after conditioned medium umbilical cord mesenchymal stem cells (secretome) therapy: mini-review. Bali Medical Journal. 2023;12(1):7-10. DOI:10.15562/bmj.v12i1.3790

[4]. Lee S-J, Bhasin S, Klickstein L, Krishnan V, Rooks D. Challenges and Future Prospects of Targeting Myostatin/Activin A Signaling to Treat Diseases of Muscle Loss and Metabolic Dysfunction. The Journals of Gerontology: Series A. 2023:glad033.DOI:10.1093/gerona/glad033

[5]. Silva MZC, Vogt BP, Reis NSC, Minicucci FC, Dorna MS, Minicucci MF, et al. Serum myostatin levels are associated with physical function and hospitalization in peritoneal dialysis patients. European Journal of Clinical Nutrition. 2023;77(2):292-4.doi:10.1038/s41430-022-01227-x.

[6]. Hanson AM, Young MH, Harrison BC, Zhou X, Han H, Stodieck LS, et al. Inhibiting myostatin signaling partially mitigates structural and functional adaptations to hindlimb suspension in mice. npj Microgravity. 2023;9(1):2. DOI:10.1038/s41526-022-00233-4.

[7]. Santos HO, Cerqueira HS, Tinsley GM. The Effects of Dietary Supplements, Nutraceutical Agents, and Physical Exercise on Myostatin Levels: Hope or Hype? Metabolites. 2022;12(11):1146. DOI:10.3390/metabo12111146.

[8]. Lee S-J. Quadrupling muscle mass in mice by targeting TGF-ß signaling pathways. PloS one. 2007;2(8):e789.DOI:10.1371/journal.pone.0000789.

[9]. Amani-Shalamzari S, Farhani F, Rajabi H, Abbasi A, Sarikhani A, Paton C, et al. Blood flow restriction during futsal training increases muscle activation and strength. Frontiers in physiology. 2019;10:614. DOI:10.3389/fphys.2019.00614

[10]. Shabkhiz, F, Chubineh, S, Ghafarian Isfahani, A, Yari, M, Response of serum myostatin to a bout of resistance training with and without blood flow restriction in immature male athletes. Physiology and management research in sports. 2016, 9-19 [in Persian].

[12]. Signorile PG, Viceconte R, Vincenzi B, Baldi A. Differential Expression in Endometriosis Tissue versus Endometrium of the Uterine Adenogenesis Factors PRL-R, GH, IGF1, and IGF2. Critical Reviews™ in Eukaryotic Gene Expression. 2023;33(3).DOI:10.1615/CritRevEukaryotGeneExpr.2022045360.

[13]. Kohama EB, da Silva ASR, Rocha A, Puggina EF, Fornel R, Custódio R, et al. IGF-I and IGFBP-3 are modulated in adolescents during a competitive soccer season. 2023. 10.22271/kheljournal.2023.v10.i1d.2779

[14]. Lopes KG, Bottino DA, Farinatti P, de Souza MdGC, Maranhão PA, de Araujo CMS, et al. Strength training with blood flow restriction–a novel therapeutic approach for older adults with sarcopenia? A case report. Clinical Interventions in Aging. 2019:1461-9. DOI:10.2147/CIA.S206522.

[15]. Torpel A, Brennicke M, Kuck M, Behrendt T, Schega L. Effect of blood flow restriction training in combination with a high-intensity interval training on physical performance. Int J Sport Exerc Med. 2018;10:2469-5718.DOI:10.23937/2469-5718/1510111

[16]. Chen HT, Chung YC, Chen YJ, Ho SY, Wu HJ. Effects of different types of exercise on body composition, muscle strength, and IGF‐1 in the elderly with sarcopenic obesity. Journal of the American Geriatrics Society. 2017;65(4):827-32.DOI:10.1111/jgs.14722.

[17]. Abe T, Yasuda T, Midorikawa T, Sato Y, CF K, Inoue K, et al. Skeletal muscle size and circulating IGF-1 are increased after two weeks of twice-daily "KAATSU" resistance training. International Journal of KAATSU Training Research. 2005;1(1):6-12.DOI:10.3806/IJKTR.1.6.

[18]. Laurentino GC, Loenneke JP, Ugrinowitsch C, Aoki MS, Soares AG, Roschel H, et al. Blood-flow-restriction-training-induced hormonal Response is not Associated with Gains in Muscle Size and Strength. Journal of human kinetics. 2022;83(1):235-43. DOI: 10.2478/hukin-2022-0095.

[19]. EBRAHIMNIA M, HOSSEINI KSA, HAGHIGHI AH. The Effect Of Three Combined Training Methods (Aerobic And Resistance) With And Without Vascular Occlusion On Some Indices Of Hypertrophy In Elderly Women. 2019.1(22): 82-97 [in Persian].

[20]. Behringer M, Behlau D, Montag JC, McCourt ML, Mester J. Low-intensity sprint training with blood flow restriction improves 100-m dash. The Journal of Strength & Conditioning Research. 2017;31(9):2462-72. DOI:10.1519/JSC.0000000000001746.

[21]. Novak S, Madunic J, Shum L, Vucetic M, Wang X, Tanigawa H, et al. PDGF inhibits BMP2-induced bone healing. npj Regenerative Medicine. 2023;8(1):3. DOI: 10.1038/s41536-023-00276-5.

[23]. Rahimi M, Ghaforyan S, Asad MR, Abbasi A. The Effect of Exercise with Different Intensity on Platelet-Derived Growth Factor Gene Expression in Visceral and Subcutaneous Adipose Tissue of Rats. Report of Health Care. 2017;3(3):37-45. [in Persian]

[24]. Palmefors H, DuttaRoy S, Rundqvist B, Börjesson M. The effect of physical activity or exercise on key biomarkers in atherosclerosis–a systematic review. Atherosclerosis. 2014;235(1):150-61. DOI:10.1016/j.atherosclerosis.2014.04.026.

[25]. Czarkowska-Paczek B, Zendzian-Piotrowska M, Bartlomiejczyk I, Przybylski J, Gorski J. The influence of physical exercise on the generation of TGF-β1, PDGF-AA, and VEGF-A in adipose tissue. European journal of applied physiology. 2011;111:875-81.DOI: 10.1007/s00421-010-1693-2.

[26]. Barari A, Bashiri J, Sarabandi M. The effect of circuit resistance training combined with ginseng supplementation levels of VEGF and PDGF in inactive females. Medical Journal of Tabriz University of Medical Sciences. 2015;37(5):6-13. [in Persian]

[30]. Zhang T, Wang X, Wang J. Effect of blood flow restriction combined with low-intensity training on the lower limbs muscle strength and function in older adults: A meta-analysis. Experimental Gerontology. 2022:111827.DOI:10.1016/j.exger.2022.111827.

[32]. Lim ZX, Goh J. Effects of blood flow restriction (BFR) with resistance exercise on musculoskeletal health in older adults: a narrative review. European Review of Aging and Physical Activity. 2022;19(1):1-16. DOI:10.1186/s11556-022-00294-0.

[33]. Rezaee Z, Javaheri SAAH, Rashidlamir A, Oral O, Stavropoulos E. Effects of BFR training in serum NRG-1 and IL-6 in overweight postmenopausal women, 2022, 27(4):541-554.

[34]. Vakili J, Amirsasan R, Sanei P. Effects of 4 weeks resistance training with and without blood flow restriction on GH, IGF-1, NO, and Lactate in male rock climbers. Journal of Sport Biosciences. 2022;14(1):33-48.DOI: 10.22059/jsb.2021.323313.1468 [in Persian].

[35]. Jensen AE, Palombo LJ, Niederberger B, Turcotte LP, Kelly KR. Exercise training with blood flow restriction has little effect on muscular strength and does not change IGF-1 in fit military warfighters. Growth Hormone & IGF Research. 2016;27:33-40.DOI:10.1016/j.ghir.2016.02.003.

[36]. Arnarson A, Geirsdottir OG, Ramel A, Jonsson P, Thorsdottir I. Insulin-like growth factor-1 and resistance exercise in community-dwelling old adults. The journal of nutrition, health & aging. 2015;19:856-60. DOI:10.1007/s12603-015-0547-3.

[37]. Manini TM, Yarrow JF, Buford TW, Clark BC, Conover CF, Borst SE. Growth hormone responses to acute resistance exercise with vascular restriction in young and old men. Growth Hormone & IGF Research. 2012;22(5):167-72. DOI:10.1016/j.ghir.2012.05.002.

[38]. Pazokian F, Amani-Shalamzari S, Rajabi H. Effects of functional training with blood occlusion on the irisin, follistatin, and myostatin myokines in elderly men. European Review of Aging and Physical Activity. 2022;19(1):22. Doi:10.1186/s11556-022-00303-2.

[41]. Santos A, Neves Jr M, Gualano B, Laurentino G, Lancha Jr A, Ugrinowitsch C, et al. Blood flow restricted resistance training attenuates myostatin gene expression in a patient with inclusion body myositis. Biology of sport. 2014;31(2):121-4. DOI:10.5604/20831862.1097479.

[43]. Khoubi M, Habibi A, Ghanbarzadeh M, Shakerian S, Mirzaii B. Acute interval waking with blood flow restriction could not increase ERK, p38 and decrease myostatin. The Journal of Sports Medicine and Physical Fitness. 2020;60(1):32-6. DOI:10.23736/S0022-4707.18.09200-9.

[45]. Mohammadi, R, Afrondeh, R, Khaje Landi, M, Mohammadian, M. Investigating the acute effect of resistance training with and without blood flow restriction on indicators related to muscle hypertrophy. Rehabilitation medicine, 2019, 147-155, DOI:10.22037/jrm.2019.112040.2146. [in Persian]

[46]. Soomro A, Khajehei M, Li R, O’Neil K, Zhang D, Gao B, et al. A therapeutic target for CKD: activin A facilitates TGFβ1 profibrotic signaling. Cellular & Molecular Biology Letters. 2023;28(1):10. DOI:10.1186/s11658-023-00424-1.

[47]. Aoki MS, Soares AG, Miyabara EH, Baptista IL, Moriscot AS. Expression of genes related to myostatin signaling during rat skeletal muscle longitudinal growth. Muscle & Nerve: Official Journal of the American Association of Electrodiagnostic Medicine. 2009;40(6):992-9. DOI:10.1002/mus.21426.

[48]. Arabzadeh E, Ghassemi Gil-kalayeh Z, Gholami M, Abed Natanzi H, Ebrahimi S. The effect of 8 weeks of circuit resistance training on serum levels of decorin and IGF-I in sedentary young men. Sport Sciences for Health. 2023:1-7. DOI:10.1007/s11332-022-01035-7.

[49]. Elham Wasadi*\, Farhad Gholami, Elham Mortazavi. 1400. The effect of eight weeks of exercise with different intensities on decorin and TGF-β gene expression in adult male rats. Ilam University of Medical Sciences 2. 86-94. DOI:10.52547/sjimu.29.2.86 [in Persian].

[50]. Elham Wasadi, Farhad Gholami, Elham Mortazavi. 1400. The effect of eight weeks of exercise with different intensities on decorin and TGF-β gene expression in adult male rats. Ilam University of Medical Sciences 2. 86-94.DOI:10.52547/sjimu.29.2.86 [in persian].

[51]. Jalal Shirzad, Asghar Tawfighi, Javad Toloui Azar, Mohammad Hassan Khadim Ansari. 2019. Adaptation of serum irisin, follistatin, and myostatin to eight weeks of resistance, aerobic, and combined training in obese men. Physiology and management research in sports 4. 21-39. [in Persian]

[53]. Hansen J, Brandt C, Nielsen AR, Hojman P, Whitham M, Febbraio MA, et al. Exercise induces a marked increase in plasma follistatin: evidence that follistatin is a contraction-induced hepatokine. Endocrinology. 2011;152(1):164-71.DOI:10.1210/en.2010-0868.

[54]. Renzini A, D’onghia M, Coletti D, Moresi V. Histone deacetylases as modulators of the crosstalk between skeletal muscle and other organs. Frontiers in physiology. 2022:282.DOI:10.3389/fphys.2022.706003.

[55]. Hansen JS, Rutti S, Arous C, Clemmesen JO, Secher NH, Drescher A, et al. Circulating follistatin is liver-derived and regulated bشy the glucagon-to-insulin ratio. The Journal of Clinical Endocrinology & Metabolism. 2016;101(2):550-60.DOI:10.1210/jc.2015-3668.

[56]. Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, et al. A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy. Cell. 2012;151(6):1319-31.DOI: 10.1016/j.cell.2012.10.050.

دوره 16، شماره 1 - شماره پیاپی 99فروردین 1403صفحه 77-90

دوره 16، شماره 1 - شماره پیاپی 99
فروردین 1403
صفحه 77-90