نشریه علوم زیستی ورزشی

اثر حاد و مزمن فعالیت رکاب زدن زیربیشینه همراه با محدودیت جریان خون برBDNF و TNFα سرمی مردان فعال

نوع مقاله : مقاله پژوهشی

نویسندگان

سعید رحمتی 1
حمید رجبی 2
لطیفه کریمزاده 3

1 دانشجوی دکتری فیزیولوژی ورزشی، دانشکدۀ تربیت بدنی و علوم ورزشی، دانشگاه تهران، تهران، ایران

2 دانشیار فیزیولوژی ورزشی، دانشکدۀ تربیت بدنی و علوم ورزشی، دانشگاه خوارزمی، تهران، ایران

3 کارشناس‌ارشد زیست‌شناسی، دانشکدۀ علوم زیستی، دانشگاه خوارزمی، تهران، ایران

https://doi.org/10.22059/jsb.2016.59099
چکیده
 این مطالعه به‌منظور تعیین اثر حاد و مزمن فعالیت رکاب زدن زیربیشینه همراه با محدودیت جریان خون بر سطح سرمی BDNF، TNF-α و نسبت BDNF به TNF-αدر مردان فعال انجام گرفت. 24 نفر از دانشجویان تربیت بدنی دانشگاه خوارزمی داوطلب شرکت در پژوهش شدند و به سه گروه رکاب زدن همراه با انسداد عروق پا (8n=)، رکاب زدن بدون انسداد (8n=) و کنترل (8n=) تقسیم شدند. آزمودنی‌های گروه تمرین با انسداد و تمرین بدون انسداد به مدت 3 هفته، هر هفته 3 جلسه و در مجموع 9 جلسه تمرین کردند. هر جلسۀ تمرین شامل 3 وهلۀ سه‌دقیقه‌ای رکاب زدن با شدت50 درصد Wmax بود و بین هر وهله 45-30 ثانیه استراحت وجود داشت (میزان فشار روی ران در گروه انسداد،170-140 میلی‌متر جیوه بود). برای تجزیه‌وتحلیل داده‌ها، از آزمون­های تحلیل واریانس یکسویه، t مستقل و t وابسته استفاده شد. نتایج نشان داد انسداد عروق پا هنگام فعالیت زیربیشینۀ رکاب زدن بر پاسخ سطوح BDNF(290/0 P=)، TNF-α(338/ 0P=) و نسبت BDNF به TNF-α(384/0 P=) در مقایسه با گروه­ بدون انسداد تفاوت معناداری ندارد. از طرفی به‌هنگام سازگاری، در سطوح BDNF(254/0 P=)، TNF-α(338/ 0P=) و نسبت BDNF به TNF-α(384/0 P=) بین گروه­های انسداد، بدون انسداد و کنترل نیز تفاوت معناداری مشاهده نشد. نتایج نشان داد که محدودیت جریان خون موضعی اثر مثبت یا منفی بر میزان BDNF، TNF-αو نسبت آنها ندارد.

کلیدواژه‌ها

تمرین انسدادی
عامل رشد عصبی مشتق شده از مغز
عامل نکروز توموری آلفا
محدودیت جریان خون

عنوان مقاله English

The Chronic and Acute Effect of Submaximal Pedaling Activity along with Blood Flow Restriction on Serum BDNF and TNF-α in Active Men

نویسندگان English

Saeed Rahmati 1
Hamid Rajabi 2
Latifeh Karimzadeh 3
1 corresponding authur
2 Researcher
3 Researcher
چکیده English

This study aimed at determining the chronic and acute effect of submaximal pedaling activity along with blood flow restriction on serum BDNF, TNF-α and BDNF/TNF-α ratio in active men. 24 physical education students at Kharazmi University volunteered for the study. They were divided into three groups: pedaling with lower extremity vascular occlusion (n=8), pedaling without occlusion (n=8), and control (n=8). Subjects in the occlusion and non-occlusion groups exercised for 3 weeks, 3 sessions per week (9 sessions totally). Each session included three 3-min. phases of pedaling at 50% of maximum power (Wmax) with 30–45 s rest interval between each two phases. The pressure on the thigh in the occlusion group was 140–170 mmHg. To analyze the data, one-way analysis of variance and independent and dependent t tests were used. Results showed that leg vessels occlusion during submaximal pedaling had no significant differences on response of BDNF (P=0.290)، TNF-α (P=0.338) and their ratio (P=0.384) compared with the non-occlusion group. In addition, in the compatibility phase, there were no significant differences in BDNF (P=0.254)، TNF-α (P=0.338) and their ratio (P=0.384) among occlusion, non-occlusion and control groups. Results showed that local blood flow restriction had no positive or negative effects on the amounts of BDNF, TNF-α and their ratio.

کلیدواژه‌ها English

blood flow restriction (BFR)
brain derived neurotrophic factor (BDNF)
occlusion training
tumor necrosis factor alpha (TNF-α)
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نشریه علوم زیستی ورزشی
دوره 8، شماره 2
تابستان 1395
صفحه 247-262

  • تاریخ دریافت 30 آذر 1393
  • تاریخ بازنگری 02 اردیبهشت 1394
  • تاریخ پذیرش 02 اردیبهشت 1394

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