اثر مکمل‌یاری عصارۀ برگ زیتون و تمرینات دایره‌ای با شدت بالا بر سطوح سرمی سالوسین آلفا و بتا و مقاومت به انسولین در زنان سالمند چاق

بهرام, زهرا; پوروقار, محمدجواد; بهرام, محمد ابراهیم

doi:10.22059/jsb.2025.399677.1682

نوع مقاله : مقاله پژوهشی Released under CC BY-NC 4.0 license I Open Access I

نویسندگان

گروه تربیت بدنی و علوم ورزشی، دانشکدة علوم انسانی، دانشگاه کاشان، کاشان، ایران.

10.22059/jsb.2025.399677.1682

چکیده

مقدمه: التهاب سیستمیک از نشانه‌های رایج دوران سالمندی مرتبط با چاقی است که سطوح سایتوکین‌های آترواسکلروزیس به میزان دو تا چهار برابر افزایش می‌یابد. هدف از تحقیق حاضر بررسی تأثیر هشت هفته تمرین دایره‌ای با شدت بالا (HICT) و مصرف مکمل عصارۀ برگ زیتون بر سطوح سرمی سالوسین آلفا و بتا و مقاومت به انسولین در زنان سالمند چاق بود.
روش پژوهش: در این تحقیق نیمه‌تجربی 40 زن سالمند چاق به‌طور تصادفی و مساوی در چهار گروه دارونما، مکمل، تمرین و مکمل+تمرین قرار گرفتند. تمرینات HICT به مدت هشت هفته و سه جلسه در هفته به مدت 45 تا 60 دقیقه انجام شد. آزمودنی‌ها به مدت هشت هفته، روزی یک عدد کپسول 125 میلی‌گرمی عصارۀ برگ زیتون را بعد از ناهار مصرف کردند. پیش و پس از آزمون، از هر چهار گروه، نمونۀ خونی اخذ شد. تجزیه‌وتحلیل داده‌ها با استفاده از آزمون آنوای یکطرفه و آزمون تعقیبی توکی و t همبسته در سطح معنا‌داری 05/0P< انجام شد.
یافته‌ها: نتایج بین‌گروهی آنوای یکطرفه نشان داد مقادیر سالوسین آلفا (001/0=P، 66/18=F) افزایش معنا‌دار و سالوسین بتا (001/0=P، 73/11=F) و مقاومت به انسولین (001/0=P، 23/30=F) کاهش معنا‌داری داشت. نتایج تی زوجی نشان داد در گروه‌های تمرین و تمرین+ عصاره کاهش معنادار سالوسین بتا و مقاومت به انسولین و افزایش معنا‌دار سالوسین آلفا مشاهده شد.
نتیجه‌گیری: به‌نظر می‌رسد تجویز تمرینات HICT در کنار مصرف عصارۀ برگ زیتون در سالمندان چاق بیشترین تأثیر را در بهبود شاخص‌های آترواسکلروزیس و مقاومت به انسولین در زنان سالمند چاق داشته باشد.

کلیدواژه‌ها

موضوعات

فیزیولوژی ورزشی

عنوان مقاله [English]

The Effect of Olive Leaf Extract Supplementation and High-Intensity Circuit Training on Serum Salusin Alpha and Beta Levels and Insulin Resistance in Obese Elderly Women

نویسندگان [English]

Zahra Bahram
Mohammad javad Pourvaghar
Mohammad Ebrahim Bahram

Department of Sports Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran.

چکیده [English]

Introduction: Systemic inflammation is a common symptom of obesity-related aging, with levels of atherosclerotic cytokines increasing two- to fourfold. The present study aimed to investigate the effect of eight weeks of high-intensity circuit training (HICT) and olive leaf extract supplementation on serum Salusin alpha and beta levels and insulin resistance in obese elderly women.
Methods: In this quasi-experimental study, 40 obese elderly women were randomly assigned to four equal groups: Placebo, Supplement, Exercise, and Supplement + Exercise. The HICT protocol was performed three times per week for eight weeks, with each session lasting 45 to 60 minutes. The Participants in the supplement groups consumed one 125 mg capsule of olive leaf extract daily after lunch for eight weeks. Blood samples were collected from all four groups before and after the test. Data were analyzed using one-way ANOVA, Tukey’s post hoc test, and paired t-test at a significance level of P < 0.05.
Results: The results of one-way ANOVA revealed a significant increase in salusin alpha (P=0.001, F=18.66) and significant decreases in salusin beta (P=0.001, F=11.73) and insulin resistance (P=0.001, F=23.30) across the groups. The results of the paired t-test indicated that in both the exercise and exercise + supplement groups, salusin beta and insulin resistance significantly decreased, while salusin alpha significantly increased.
Conclusion: It seems that prescribing HICT exercises along with olive leaf extract consumption exerts the greatest beneficial effect on improving atherosclerosis markers and insulin resistance in obese elderly women.

کلیدواژه‌ها [English]

Aging
Insulin resistance
Olive leaf extract
Salusin alpha
Salusin beta

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