Document Type : Research Paper I Open Access I Released under CC BY-NC 4.0 license

Authors

1 Master's student in Exercise Physiology, Department of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran.

2 Associate Professor of Exercise Physiology, Department of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran

3 PhD in Exercise Physiology, Department of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran.

10.22059/jsb.2025.399677.1682

Abstract

Introduction: Systemic inflammation is a common symptom of obesity-related aging, with levels of atherosclerotic cytokines increasing two- to fourfold. The aim of the present study was to investigate the effect of 8 weeks of high-intensity circuit training (HICT) and olive leaf extract supplementation on serum levels of alpha and beta and insulin resistance in obese elderly women.

Methods: In this quasi-experimental study, 40 obese elderly women were randomly assigned to four groups of placebo, supplement, exercise, and supplement + exercise equally. HICT training was performed for eight weeks and three sessions per week for 45 to 60 minutes. The subjects consumed one 125 mg capsule of olive leaf extract daily after lunch for eight weeks. Blood samples were collected from all four groups before and after the test. Data analysis was performed using one-way ANOVA test and Tukey's post hoc test and paired t-test at a significance level of P<0.05.

Results: The results of one-way ANOVA between groups showed that salosin alpha (P=0.001, F=18.66) significantly increased and salosin beta (P=0.001, F=11.73) and insulin resistance (P=0.001, F=23.30) significantly decreased. The results of paired t-test showed that in the exercise and exercise + extract groups, a significant decrease in salosin beta and insulin resistance and a significant increase in salosin alpha were observed.

Conclusion: It seems that prescribing HICT exercises along with olive leaf extract consumption in obese elderly women has the greatest effect on improving atherosclerosis indices and insulin resistance in obese elderly women.

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