Document Type : Research Paper I Open Access I Released under CC BY-NC 4.0 license


1 MSc of Exercise Physiology, Department of Exercise Physiology, Faculty of Sport Sciences, University of Isfahan, Isfahan, Iran

2 Associate Professor, Department of Exercise Physiology, Faculty of Sport Sciences, University of Isfahan, Isfahan, Iran


The main aim of this study was to evaluate the effect of high and medium intensity interval training on plasma levels of Orexin-A, lipid profile and cardiorespiratory endurance of overweight and obese women. 24 women (age range 25-45 years) volunteered and were non-randomly divided into HIIT (n=9, BMI= 29.61±3.45 kg.m2), MIIT (n=8, BMI= 28.19±3.83 kg.m2) and control (n=7, BMI=29.18±4.71 kg.m2) groups. The HIIT protocol was conducted with %75-90 of maximum HR and MIIT protocol with %60-80 of maximal HR for 8 weeks and 3 sessions per week. The findings showed a significant reduction in total cholesterol level and a significant increase in cardiorespiratory endurance of the training groups (P≤0.05). On the other hand, plasma Orexin levels increased and changed and triglyceride, LDL and body fat percent decreased in training groups compared with the control group, but these changes were not statistically significant (P≥0.05). Also, the HDL levels increased in HIIT group while they decreased in MIIT group; these changes were not statistically significant in any of the groups (P≥0.05). It seems that the interval training with different intensities increased Orexin plasma levels and improved some markers of lipid profile, body fat percent and cardiorespiratory endurance in overweight and obese women, but this improvement was more sensible in HIIT group. 


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