Document Type : Research Paper I Open Access I Released under CC BY-NC 4.0 license


1 Master's student in sports physiology and health, Faculty of Humanities, University of Kashan, Kashan, Iran

2 Associate Professor of Sports Physiology, Faculty of Humanities, University of Kashan, Kashan, Iran

3 Ph.D in Exercise physiology, educational sciences and psychology, University of Mohaghegh Ardabili, Iran



Introduction: The expression of chemerin and vaspin bioactive molecules is done through the communication between adipose tissue and other biological systems of the body, which play a role in the pathogenesis of metabolic syndrome and the pathogenesis of obesity and diabetes. The purpose of this study was the effect of eight weeks of HIRT training on the serum levels of chemerin, vaspin and factors effective in the pathogenesis of diabetes in obese and overweight prediabetic men.

Methods: In this semi-experimental study, 30 obese prediabetic men (3 0 to 45 years old) were divided into two experimental and control groups (15 people in each group). The experimental group participated in the HIRT program with an intensity of 80-85% of a maximum repetition for 8 weeks and three sessions each week for 60 minutes. The serum levels of Camrin, Vaspin and diabetes indicators were measured on two occasions before and after the test.

Results: T he results of covariance analysis showed the values of chemerin (P=0.001), vaspin (P=0.001), insulin (P=0.001), glucose (P=0.001) and insulin resistance (P=0.001) P), was significantly reduced in the experimental group compared to the control group. The intra-group results of paired t also showed a significant decrease in camrin (P=0.001, -0.90 percent), vaspin (P=0.003, -16.6 percent), insulin (P=0.001, -17.5 percent), glucose (P=0.001, -19.1%), insulin resistance (P=0.001, -40.8%) in response to the exercise protocol (P<0.05).

Conclusion: Probably, HIRT exercises can have a beneficial effect on Camrin, Vaspin and some effective indicators in diabetes and body composition in pre-diabetic obese men.


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