Sport Biosciences

Effect of 12 Weeks of Resistance and Aerobic Training on Serum Levels of CTRP-12 and LCN-2 in Women With Type-2 Diabetes

Document Type : Research Paper

Authors

Morteza Fattahpour Marandi 1
Solmaz Babaei 2

1 Department of Sports Sciences, Faculty of Humanities, University of Maragheh, Maragheh, Iran.

2 Corresponding Author, Department of Sports Sciences, Faculty of Humanities, University of Maragheh, Maragheh, Iran.

https://doi.org/10.22059/jsb.2023.357093.1581
Abstract
Introduction: Lipocalin-2 (LCN-2) and CTRP-12 are adipokines that are closely related to type-2 diabetes and are expressed in adipose tissue. Therefore, this research aimed to investigate the effect of 12 weeks of resistance and aerobic training on the serum levels of CTRP-12 and LCN-2 in women with type-2 diabetes.
Methods: The present research was conducted in a quasi-experimental manner. The statistical population of the study included all women with type-2 diabetes in Urmia city, from which 30 women with type-2 diabetes in the age range of 40-45 years old were selected and randomly assigned into three Resistance Training (three sets with 10 repetitions at 30 to 75% of 1RM), Aerobic Training (15 to 45 minutes at 50 to 75% of RHR), and Control groups. The training groups practiced for 12 weeks and three sessions per week. Serum levels of CTRP-12 and LCN-2 were measured using an ELISA kit. To analyze the data, dependent t, and ANOVA tests were used at a significance level of less than 5%.
Results: In the resistance and aerobic training groups, the values of CTRP-12 increased significantly, while the values of LCN-2 in these two groups decreased significantly compared with the control group (p<0/05). In the between-group analysis, resistance and aerobic training produced significant changes in CTRP-12 and LCN-2 compared with the control group (p<0/05).
Conclusion: It seems that performing resistance and aerobic training induces up-regulation of anti-inflammatory adipokines (CTRP-12) and a down-regulation of the inflammatory adipokine lipocalin-2 (LCN-2).

Keywords

Aerobic Training
CTRP-12
Lipocalin-2
Tesistance Training
Type-2 Diabetes
Subjects

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  • Receive Date 13 April 2023
  • Revise Date 23 May 2023
  • Accept Date 10 June 2023

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