The effect of combined training and vitamin D supplementation on some indicators of liver damage, function and depression in women addicted to methamphetamine and heroin

Document Type : Research Paper

Authors

1 3. MSc in Exercise Physiology, Department of Exercise Physiology, Faculty of Physical Education and Sport Science, University of Tabriz, Tabriz, Iran

2 2. Department of Exercise Physiology, Faculty of Physical Education and Sport Science, University of Tabriz, Tabriz, Iran.

3 tabriz university2. Department of Exercise Physiology, Faculty of Physical Education and Sport Science, University of Tabriz, Tabriz, Iran.

Abstract

Aim: determine the effect of 8 weeks of combined exercise and vitamin D supplementation on some functional indicators of liver damage and depression of women addicted to methamphetamine and heroin.

Methodology: In this quasi-experimental study, 32 addicted women (age 28.34±6.7 years, weight 62.06±10.24 and body mass index 24.10±2.93) were selected and divided into four groups. The vitamin D supplementation was eight weeks. Exercise group, resistance training with intensity of 40-70% 1RM for 18 to 28 minutes and aerobic exercise with intensity of 50-70% heart rate for 12 to 37.30 minutes in one day and 3 sessions per week for Performed for 8 weeks, before and after the protocol, blood samples were measured for ALT, AST, ALP, cravings, depression, exercise performance and muscle endurance.Sh apirovilk test was used to examine the natural distribution of data and Kruskal-Wallis test for abnormal data, ANOVA and Bonferroni post hoc test were used to compare groups at level of α <0.05.

Result :In liver AST, ALP enzymes showed a significant decrease in the exercise + supplement group compared to the supplement group (P<0.05). However, ALT enzyme was not significantly reduced in all groups (P<0.05), depression, craving, 600 m running and muscular endurance were significantly improved in the training groups compared to the control group (P <0.05), but there was no significant difference in the supplement group compared to the control group (P <0.05)

Conclusion: Combined exercise can have beneficial effects in reducing liver damage, depression, and increasing muscle function and endurance in addicted women.

Keywords

Main Subjects