Document Type : Research Paper I Open Access I Released under CC BY-NC 4.0 license


1 M.Sc. of Exercise Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran

2 Associate Professor of Exercise Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran

3 Assistant Professor of Exercise Physiology, Damghan Branch, Islamic Azad University, Damghan, Iran


One of the simplest and safest ways to treat diabetes is exercise regularly and Consumption of herbal medicines that have few side effects. The aim of this study was to evaluate the effect of high-intensity interval training with aloe vera supplementation on some selected adipokines in type 2 diabetic men. In this quasi-experimental study, 44 men with type 2 diabetes (mean age 25-40 years) were randomly divided into four groups (n=11) of control, aloe vera, exercise and exercise- aloe vera groups. High-intensity interval training were performed 3 sessions per week for 12 weeks. Subjects received an aloe vera capsule containing 100 mg of aloe vera gel powder in the morning immediately after waking up and one capsule after dinner. Blood samples and anthropometric characteristics were obtained before and after the intervention. Data were analyzed using two-way ANOVA with repeated measures, t-test and Tukey post hoc test at P<0.05. The results showed that 12 weeks of HIIT and HIIT with aloe vera supplementation significantly reduced cathepsin S, K, L levels in type 2 diabetic men (P=0.001). Also, aloe vera supplementation reduced the levels of cathepsin S, K, L, which was not statistically significant (P <0.05). It seems that 12 weeks of HIIT and HIIT with aloe vera supplementation will improve adipokines in patients with type 2 diabetes.


Main Subjects

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