Effect of eight weeks of continuous and high intensity interval training on UCP1 in visceral and subcutaneous white adipose tissue of obese rats

Document Type : Research Paper

Authors

1 MSc, Department of Biological Sciences in Sport and Health, Faculty of Sports Sciences and Health, Shahid Beheshti University, Tehran, Iran

2 Associated professor, Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

3 PHD student, Department of Biological Sciences in Sport and Health, Faculty of Sports Sciences and Health, Shahid Beheshti University, Tehran, Iran

Abstract

Prevalence of obesity and its related disease is considered as a major health complication worldwide. Change in adipose tissue phenotype caused by exercise training, consider as one of the obesity prevention strategy. The aim of this study was to investigate the effect of eight weeks of continuous and high intensity interval training (HIIT) on UCP1 of visceral and subcutaneous white adipose tissue in obese rats. 18 obese rats after eight weeks of high fat diet randomly divided into control, continuous training (CT) and HIIT groups. HIIT protocol included high intensity intervals (80-110 % vVO2max) and low intensity intervals (50 % vVO2max) and CT protocol included running with 65-75 % vVO2max intensity. 48 hours after the last training session, rats were sacrificed, visceral and subcutaneous white adipose tissue were removed and UCP1 level was assessed through western blotting method. The results showed that eight weeks of CT and HIIT increase UCP1 in visceral and subcutaneous WAT (p

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