The Effect of 4 Weeks of High Intensity Interval Training with Blood Flow Restriction on Cardiovascular Fitness and Serum Levels of IL-6 and IL-17 Inflammatory Cytokines in Active Young Men

Document Type : Research Paper

Authors

1 MSc, Department of Exercise Physiology, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran

2 . Associate Professor, Department of Physical Education & Sport Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran

3 Associate Professor, Department of Exercise Physiology, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran

Abstract

High intensity interval training and blood flow restriction make huge physiological changes in athletes. The aim of this study was to investigate the effect of 4 weeks of high intensity interval training and blood flow restriction on cardiovascular fitness and inflammatory cytokines of interleukin-6 and interleukin-17 in active male students. 18 active students in Tehran city (age range 20-30 years) were divided into three groups: 1- training and blood flow restriction, 2- training and 3-blood flow restriction by convenience sampling method. The subjects performed high intensity interval training and blood flow restriction for 4 weeks and 3 sessions per week. Fasting blood samples were collected before and after the test. Based on the results, high intensity interval training and blood flow restriction did not significantly change the Vo2max or vVo2max in the groups. According to the results, interleukin-6 and interleukin-17 levels at resting state were different among the groups. These indices showed significant differences in the training group compared with the other two groups (p < 0.05). IL-6 decreased and IL-7 increased in the training group. A decrease in the amount of resting interleukin-6 in the training group can show the relative decrease in the stress of this group. Also, a decrease in the levels of interleukin-17 in blood flow restriction groups may be attributed to the relative weakness of the immune system and the loss of function of T-helper 17 cells in these groups.

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