The Effect of 8 Weeks of Concurrent Training with L-Arginine Supplementation on 8-isoPGF2α, SOD, GPX and CAT in Elderly Men

Document Type : Research Paper I Open Access I Released under CC BY 4.0 license

Authors

1 Assistant Professor, Department of Exercise Physiology, Semnan University, Semnan, Iran

2 MSc of Exercise Physiology, Semnan University, Semnan, Iran

Abstract

The aim of this study was to evaluate the effect of 8 weeks of concurrent training with supplementation of L-arginine on SOD, GPX, CAT and 8-isoPGF2α in the male elderly. 44 male elderly (mean age: 67.77 ± 4.61, height: 168.38 ± 3.22 and weight: 70.45 ± 4.99) were selected voluntarily and purposively, and randomly divided into 4 groups (each group 11 subjects): training + supplements (ES), training + placebo (EP), supplement and control. Training groups completed 8 weeks of the training protocol every other day, 3 sessions per week. ES and supplementation groups daily received 1000 mg of L-arginine one hour after their breakfast and one hour before the training. ELISA method was used to measure biochemical variables and analysis of variance was used to analyze data at PP<0.001). Also, univariate analysis of variance showed the significant effect of group on every variable of oxidative stress (P<0.001). According to the findings of this study, elderly men could benefit from the effect of concurrent resistance and endurance training and consumption of 1000 mg L-arginine every day which probably reduces more oxidative stress indicator and improves their antioxidant system and could improve antioxidant defense system which improves their health.

Keywords


 
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Volume 9, Issue 4
May 2016
Pages 515-527
  • Receive Date: 06 April 2017
  • Revise Date: 29 May 2017
  • Accept Date: 26 October 2017
  • First Publish Date: 22 December 2017