An Investigation of Response of FABP5 Plasma Levels to 8 Weeks of Aerobic Exercise in Non-Menopausal and Postmenopausal Overweight Women

Document Type : Research Paper


1 MSc, Faculty of Physical Education and Sport Sciences, Mazandaran University, Babolsar, Iran.

2 Associate Professor, Faculty of Physical Education and Sport Sciences, Mazandaran University, Babolsar, Iran


The present study investigated the response of plasma levels of FABP5 to 8 weeks of aerobic exercise in women before and after menopause. 10 non-menopausal women (mean BMI ± SD, 27.8 ± 2.03 kg/m2) and 10 postmenopausal women (mean BMI ± SD, 28.6 ± 1.5 kg/m2) were assigned to two exercise groups. The program included 8 weeks of aerobic exercise, 3 sessions per week at 40-80% of maximal reserved heart rate. Each session lasted 25 minutes in the first week and it increased up to 45 minutes in the 8th week of exercise. Plasma levels of FABP5 and lipid profile were measured before and after the exercise period. The exercise significantly increased FABP5 in the postmenopausal group (P<0.05). LDL levels significantly increased in postmenopausal group and cholesterol was associated with a significant increase in both groups (P<0.05). Increasing levels of FABP5 in menopause may follow other mechanisms and be associated with metabolic changes after exercise.


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