Document Type : Research Paper I Open Access I Released under CC BY-NC 4.0 license


1 MSc of Exercise Physiology, Faculty of Physical Education and Sports Sciences, University of Mazandaran, Babolsar, Iran

2 MSc of Exercise Physiology, Science and Research University of Kohkilouye and Boyer Ahmad, Yasouj, Iran

3 MSc of Exercise Physiology, Department of Physical Education and Sports Sciences, University of Shiraz, Shiraz, Iran

4 Assistant Professor of Exercise Physiology, Faculty of Physical Education and Sports Sciences, University of Shahrkord, Shahrkord, Iran


The aim of this study was to investigate the effect of acute plyometric exercise with and without vitamin C supplementation on serum BDNF concentration in inactive men. In this semi-experimental study, 36 inactive men were randomly divided into four groups: vitamin+exercise (combination), vitamin C, exercise, and control. The exercise and combination groups performed the selected plyometric protocol. Also, vitamin and combination groups consumed a 500-mg vitamin C capsule daily for 1 week. Blood samples were collected before and after the exercise protocol in order to measure BDNF. BDNF levels were measured by a laboratory kit and ELIZA method. Independent t test, one-way ANOVA and Tukey post hoc test were used to compare the differences of the groups. Serum BDNF levels significantly changed after consumption of vitamin C and acute plyometric exercise compared with control group. Also, vitamin C consumption with no exercise significantly increased serum BDNF; but plyometric exercise alone could not significantly change serum BDNF concentration. It seems that plyometric exercise with vitamin C may be beneficial to extend cognitive and functional benefits of the brain.


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