Document Type : Research Paper I Open Access I Released under CC BY-NC 4.0 license


1 MSc of Exercise Physiology, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran

2 Professor, Department of Exercise Physiology, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran

3 Ph.D. of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran


KAATSU training is effective and beneficial to improve different physical factors and is associated with lower muscular injury and inflammation. So, the aim of this study was to compare the effect of KAATSU training and no blood flow restriction on changes of growth hormone, insulin-like growth factor-1 and lactate in healthy young men. This study was semi-experimental with a repeated measurements design. It also used a counterbalance design. 10 young men (20-25 years old and BMI 21.36 kg/m2) were selected by a public call. KAATSU first session of resistance training started 72 hours after 1 RM was determined and blood pressure of quadriceps was evaluated. One week after the first session of KAATSU training, similar subjects performed the resistance training without blood flow restriction. Then, blood samples were collected in three phases to measure the mentioned variables. Results showed that lactate and growth hormone levels significantly increased in both groups especially after the second blood sampling (P<0.05). However, results showed that IGF-1 significantly increased immediately after KAATSU training in comparison with training without blood flow restriction (P<0.05). It can be concluded that the pattern of changes in concentration of blood lactate and growth hormone was similar in both groups. Pearson correlation coefficient of the three factors showed that only the relationship between hGH and lactate was significant in KAATSU group. In addition, this training significantly increased IGF-1 in KAATSU group compared with the other group.


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