Document Type : Research Paper I Open Access I Released under CC BY-NC 4.0 license
Authors
1 student
2 Deputy shahid Chamran University School of Physical Education
Abstract
The aim of this study was to evaluate the effect of 8 weeks of combined station training on the adiponectin and hs-CRP in overweight women. 22 overweight women (mean ± SD, age 26.04±4.43 years; weight 73.10±6.56 kg; body mass index 29.35±2.53) were voluntarily selected and randomly divided into control (n=11) and combined station training (n=11) groups. The subjects of combined station training practiced for 8 weeks, 4 sessions per week with an intensity of 70–90% MHR. Blood samples were collected in a fasting state before practice and 48 hours after the last training session. ELISA was used to measure hormonal variables. For data analysis, ANCOVA analysis was used. After 8 weeks of combined station training, the levels of adiponectin in experimental group increased significantly (P=0.001) while the levels of hs-CRP decreased (P=0.001). It seems that due to anti-inflammatory effects, combined station training with high intensity may be an effective therapy to prevent and improve risk factors for chronic obesity-related diseases such as cardiovascular diseases, diabetes, etc. in sedentary overweight young women.
Keywords
- دبیدی روشن، ولیالله؛ گائینی، عباسعلی؛ ناموراصل، نبیالله (1386). تأثیر چهار هفته بیتمرینی بر پروتئین واکنشدهندۀ C موشهای صحرایی. فصلنامة المپیک، ش 1، بهار، ص 69-61.
- Bahceci, M., Gokalp, D., Bahceci, S., Tuzcu, A., Atmaca, S., Arikan, S. (2007). “The correlation between adiposity and adiponectin, tumor necrosis factor α, interleukin-6 and high sensitivity C-reactive protein levels”. Is adipocyte size associated with inflammation in adults?. Journal of endocrinological investigation, 30(3), 210-214.
- Blake, G. J., Ridker, P. M. (2001). “Novel clinical markers of vascular wall inflammation”. Circulation research, 89(9), 763-771.
- Boudou, P., Sobngwi, E., Mauvais-Jarvis, F., Vexiau, P., Gautier, J. F. (2003).” Absence of exercise-induced variations in adiponectin levels despite decreased abdominal adiposity and improved insulin sensitivity in type 2 diabetic men”. European Journal of Endocrinology, 149(5), 421-424.
- Calabró, P., Willerson, J. T., Yeh, E. T. (2003). “Inflammatory cytokines stimulated C-reactive protein production by human coronary artery smooth muscle cells”. Circulation, 108(16), 1930-1932.
- Engeli, S., Feldpausch, M., Gorzelniak, K., Hartwig, F., Heintze, U., Janke, J., Sharma, A. M. (2003). “Association between adiponectin and mediators of inflammation in obese women”. Diabetes, 52(4), 942-947.
- Esmaillzadeh, A., Azadbakht, L. (2008). “Major dietary patterns in relation to general obesity and central adiposity among Iranian women". The Journal of nutrition, 138(2), 358-363.
- Fantuzzi, G. (2008). “Adiponectin and inflammation: consensus and controversy”.Journal of Allergy and Clinical Immunology, 121(2), 326-330.
- Ford, E. S. (2002). “Does exercise reduce inflammation? Physical activity and C-reactive protein among US adults”. Epidemiology, 13(5), 561-568.
- Frühbeck, G., Salvador, J. (2004). “Role of adipocytokines in metabolism and disease”. Nutrition Research, 24(10), 803-826.
- Ghorbani, A., Parastesh, M. (2011). "Relationship between adiponectin and insulin resistance in type II diabetic men after aerobic training". Arak Medical University Journal, 14(2), 43-50.
- Guebre-Egziabher, F., Bernhard, J., Funahashi, T., Hadj-Aissa, A., Fouque, D. (2005). “Adiponectin in chronic kidney disease is related more to metabolic disturbances than to decline in renal function”. Nephrology Dialysis Transplantation, 20(1), 129-134.
- Hamedinia, M., Haghighi, A., Ravasi, A. (2007). “The effect of aerobic training on inflammatory factors. of heart disease in obese men”. Iranian Journal of Harkat, 34, 47-58.
- Hammett, C. J., Prapavessis, H., Baldi, J. C., Varo, N., Schoenbeck, U., Ameratunga, R., Stewart, R. A. (2006). “Effects of exercise training on 5 inflammatory markers associated with cardiovascular risk”. American heart journal, 151(2), 367-e7.
- Hersoug, L. G., Linneberg, A. (2007). “The link between the epidemics of obesity and allergic diseases: does obesity induce decreased immune tolerance?”. Allergy, 62(10), 1205-1213.
- Hoffman, J. (2014). Physiological aspects of sport training and performance. Human Kinetics
- Horowitz, J. F., Leone, T. C., Feng, W., Kelly, D. P., Klein, S. (2000). “Effect of endurance training on lipid metabolism in women: a potential role for PPARα in the metabolic response to training”. American Journal of Physiology-Endocrinology And Metabolism, 279(2), E348-E355.
- Jones, L. W., Eves, N. D., Peddle, C. J., Courneya, K. S., Haykowsky, M., Kumar, V., ... Reiman, T. (2009). “Effects of presurgical exercise training on systemic inflammatory markers among patients with malignant lung lesions”.Applied Physiology, Nutrition, and Metabolism, 34(2), 197-202.
- Kahn, C. R. (2000). “Triglycerides and toggling the tummy”. Nature genetics,25(1), 6-7.
- Kasapis, C., Thompson, P. D. (2005). “The effects of physical activity on serum C-reactive protein and inflammatory markers”: a systematic review.Journal of the American College of Cardiology, 45(10), 1563-1569.
- Kim, K., Valentine, R. J., Shin, Y., Gong, K. (2008).” Associations of visceral adiposity and exercise participation with C-reactive protein, insulin resistance, and endothelial dysfunction in Korean healthy adults”. Metabolism, 57(9), 1181-1189.
- Kobayashi, J., Murase, Y., Asano, A., Nohara, A., Kawashiri, M. A., Inazu, A., ... Mabuchi, H. (2006).” Effect of walking with a pedometer on serum lipid and adiponectin levels in Japanese middle-aged men”. Journal of atherosclerosis and thrombosis, 13(4), 197-201.
- Koh, E. H., Park, J. Y., Park, H. S., Jeon, M. J., Ryu, J. W., Kim, M., ... Lee, K. U. (2007). “Essential role of mitochondrial function in adiponectin synthesis in adipocytes”. Diabetes, 56(12), 2973-2981.
- Kondo T, Kobayashi I, Murakami M.2006. Effect of exercise on circulating adipokine levels in obese young women. J Endocrinol; 53(2):189-95.
- Kraemer, R. R., Castracane, V. D. (2007). “Exercise and humoral mediators of peripheral energy balance: ghrelin and adiponectin”. Experimental biology and medicine, 232(2), 184-194.
- Laughlin, G. A., Barrett-Connor, E., May, S., Langenberg, C. (2007). “Association of adiponectin with coronary heart disease and mortality the rancho bernardo study”. American journal of epidemiology, 165(2), 164-174.
- Lazar, M. A. (2006). “The humoral side of insulin resistance”. Nature medicine,12(1), 43-43.
- Leggate, M., Nowell, M. A., Jones, S. A., Nimmo, M. A. (2010). “The response of interleukin-6 and soluble interleukin-6 receptor isoforms following intermittent high intensity and continuous moderate intensity cycling”. Cell stress and Chaperones, 15(6), 827-833.
- Marcell, T. J., McAuley, K. A., Traustadóttir, T., Reaven, P. D. (2005). “Exercise training is not associated with improved levels of C-reactive protein or adiponectin”. Metabolism, 54(4), 533-541.
- Matsushita, K., Yatsuya, H., Tamakoshi, K., Wada, K., Otsuka, R., Zhang, H., ... Toyoshima, H. (2006). “Inverse association between adiponectin and C-reactive protein in substantially healthy Japanese men”. Atherosclerosis, 188(1), 184-189.
- Meyer, A. A., Kundt, G., Lenschow, U., Schuff-Werner, P., Kienast, W. (2006). “Improvement of early vascular changes and cardiovascular risk factors in obese children after a six-month exercise program”. Journal of the American College of Cardiology, 48(9), 1865-1870.
- Moghadasi M, Mohebbi H, Rahmani-Nia F, Hassan-Nia S, Noroozi H, Pirooznia N.(2012)“Highintensity endurance training improves adiponectin mRNA and plasma concentrations”.European journal of applied physiology.; 112(4):1207-1
- Murphy, M. H., Murtagh, E. M., Boreham, C. A., Hare, L. G., Nevill, A. M. (2006). “The effect of a worksite based walking programme on cardiovascular risk in previously sedentary civil servants” [NCT00284479]. BMC Public Health, 6(1), 136.
- Olson, T. P., Dengel, D. R., Leon, A. S., Schmitz, K. H. (2007). “Changes in inflammatory biomarkers following one-year of moderate resistance training in overweight women”. International journal of obesity, 31(6), 996-1003.
- Ouchi, N., Kihara, S., Funahashi, T., Nakamura, T., Nishida, M., Kumada, M., ... Matsuzawa, Y. (2003). “Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue”. circulation, 107(5), 671-674.
- Ouchi, N., Walsh, K. (2007). “Adiponectin as an anti-inflammatory factor”.Clinicachimicaacta, 380(1), 24-30.
- Park, E., Shin, M. J., Chung, N. (2007). “The associations between serum leptin, adiponectin and intercellular adhesion molecule-1 in hypercholesterolemic patients”. Nutrition research and practice, 1(1), 65-69.
- Paschos, G. K., Zampelas, A., Panagiotakos, D. B., Katsiougiannis, S., Griffin, B. A., Votteas, V., Skopouli, F. N. (2007). “Effects of flaxseed oil supplementation on plasma adiponectin levels in dyslipidemic men”. European journal of nutrition, 46(6), 315-320.
- Polak, J., Klimcakova, E., Moro, C., Viguerie, N., Berlan, M., Hejnova, J., ... Stich, V. (2006). “Effect of aerobic training on plasma levels and subcutaneous abdominal adipose tissue gene expression of adiponectin, leptin, interleukin 6, and tumor necrosis factor α in obese women”. Metabolism, 55(10), 1375-1381.
- Shavandi N, Saremi A, Ghorbani A, Parastesh M.)2011("Relationship betweenadiponectiand insulin resistance in type II diabetic men after aerobic training". Arak Medical UniversityJournal.;14(2) :4350.[Persian]
- Shing, C. M., Webb, J. J., Driller, M. W., Williams, A. D., Fell, J. W. (2013). "Circulating adiponectin concentration and body composition are altered in response to high-intensity interval training". The Journal of Strength & Conditioning Research, 27(8), 2213-2218.
- Sillanpää, P. J., Peltola, E., Mattila, V. M., Kiuru, M., Visuri, T., &Pihlajamäki, H. (2009). Femoral avulsion of the medial patellofemoral ligament after primary traumatic patellar dislocation predicts subsequent instability in men a mean 7-year nonoperative follow-up study. The American journal of sports medicine,37(8), 1513-1521.
- Simpson, K. A., Singh, M. A. F. (2008). “Effects of exercise on adiponectin: a systematic review”. Obesity, 16(2), 241-256.
- Smith, J., Al-Amri, M., Sniderman, A., Cianflone, K. (2006). "Leptin and adiponectin in relation to body fat percentage, waist to hip ratio and the apoB/apoA1 ratio in Asian Indian and Caucasian men and women". NutrMetab (Lond), 3, 18.
- Stewart, L. K., Flynn, M. G., Campbell, W. W., Craig, B. A., Robinson, J. P., Timmerman, K. L., ... Talbert, E. (2007). "The influence of exercise training on inflammatory cytokines and C-reactive protein". Medicine and Science in Sports and Exercise, 39(10), 1714.
- Sun, Y., Xun, K., Wang, C., Zhao, H., Bi, H., Chen, X., Wang, Y. (2009). “Adiponectin, an unlocking adipocytokine”. Cardiovascular therapeutics, 27(1), 59-75.
- Talanian, J. L., Galloway, S. D., Heigenhauser, G. J., Bonen, A., Spriet, L. L. (2007). "Two weeks of high-intensity aerobic interval training increases the capacity for fat oxidation during exercise in women". Journal of applied physiology, 102(4), 1439-1447.
- Tchernof, A., Nolan, A., Sites, C. K., Ades, P. A., Poehlman, E. T. (2002). "Weight loss reduces C-reactive protein levels in obese postmenopausal women".Circulation, 105(5), 564-569.
- Tjønna, A. E., Lee, S. J., Rognmo, Ø., Stølen, T. O., Bye, A., Haram, P. M., ... Wisløff, U. (2008). "Aerobic Interval Training Versus Continuous Moderate Exercise as a Treatment for the Metabolic Syndrome A Pilot Study". Circulation,118(4), 346-354.
- Toth, P. P. (2005). "Adiponectin and high-density lipoprotein: a metabolic association through thick and thin". European heart journal, 26(16), 1579-1581.
- Trapp, E. G., Chisholm, D. J., Freund, J., Boutcher, S. H. (2008). "The effects of high-intensity intermittent exercise training on fat loss and fasting insulin levels of young women". International journal of obesity, 32(4), 684-691.
- Wang, Z., Nakayama, T. (2010). "Inflammation, a link between obesity and cardiovascular disease". Mediators of inflammation, 2010.
- Watts, K., Jones, T. W., Davis, E. A., Green, D. (2005). "Exercise training in obese children and adolescents". Sports Medicine, 35(5), 375-392..
- Więcek, A., Adamczak, M., Chudek, J. (2007). "Adiponectin—an adipokine with unique metabolic properties". Nephrology Dialysis Transplantation, 22(4), 981-988.
- Winer, J. C., Zern, T. L., Taksali, S. E., Dziura, J., Cali, A. M., Wollschlager, M., ... Caprio, S. (2006). "Adiponectin in childhood and adolescent obesity and its association with inflammatory markers and components of the metabolic syndrome". The Journal of Clinical Endocrinology & Metabolism, 91(11), 4415-4423.
- Yang, Q., Graham, T. E., Mody, N., Preitner, F., Peroni, O. D., Zabolotny, J. M., ... Kahn, B. B. (2005). "Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes". Nature, 436(7049), 356-362.
- YATAGAI, T., NISHIDA, Y., NAGASAKA, S., NAKAMURA, T., TOKUYAMA, K., SHINDO, M., ... ISHIBASHI, S. (2003). "Relationship between exercise training-induced increase in insulin sensitivity and adiponectinemia in healthy men". Endocrine journal, 50(2), 233-238.
- Yudkin, J. S., Kumari, M., Humphries, S. E., Mohamed-Ali, V. (2000). "Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?". Atherosclerosis, 148(2), 209-214.