Document Type : Research Paper I Open Access I Released under CC BY 4.0 license

Authors

1 student

2 Deputy shahid Chamran University School of Physical Education

Abstract

 
 
The aim of this study was to evaluate the effect of 8 weeks of combined station training on the adiponectin and hs-CRP in overweight women. 22 overweight women (mean ± SD, age 26.04±4.43 years; weight 73.10±6.56 kg; body mass index 29.35±2.53) were voluntarily selected and randomly divided into control (n=11) and combined station training (n=11) groups. The subjects of combined station training practiced for 8 weeks, 4 sessions per week with an intensity of 70–90% MHR. Blood samples were collected in a fasting state before practice and 48 hours after the last training session. ELISA was used to measure hormonal variables. For data analysis, ANCOVA analysis was used. After 8 weeks of combined station training, the levels of adiponectin in experimental group increased significantly (P=0.001) while the levels of hs-CRP decreased (P=0.001). It seems that due to anti-inflammatory effects, combined station training with high intensity may be an effective therapy to prevent and improve risk factors for chronic obesity-related diseases such as cardiovascular diseases, diabetes, etc. in sedentary overweight young women.

Keywords

  1. دبیدی روشن، ولی‌الله؛ گائینی، عباسعلی؛ ناموراصل، نبی‌الله (1386). تأثیر چهار هفته بی‌تمرینی بر پروتئین واکنش‌دهندۀ C موش‌های صحرایی. فصلنامة المپیک، ش 1، بهار، ص 69-61.

 

 

  1. Bahceci, M., Gokalp, D., Bahceci, S., Tuzcu, A., Atmaca, S., Arikan, S. (2007). “The correlation between adiposity and adiponectin, tumor necrosis factor α, interleukin-6 and high sensitivity C-reactive protein levels”. Is adipocyte size associated with inflammation in adults?. Journal of endocrinological investigation30(3), 210-214.
  2. Blake, G. J., Ridker, P. M. (2001). “Novel clinical markers of vascular wall inflammation”. Circulation research89(9), 763-771.
  3. Boudou, P., Sobngwi, E., Mauvais-Jarvis, F., Vexiau, P., Gautier, J. F. (2003).” Absence of exercise-induced variations in adiponectin levels despite decreased abdominal adiposity and improved insulin sensitivity in type 2 diabetic men”. European Journal of Endocrinology149(5), 421-424.
  4. Calabró, P., Willerson, J. T., Yeh, E. T. (2003). “Inflammatory cytokines stimulated C-reactive protein production by human coronary artery smooth muscle cells”. Circulation108(16), 1930-1932.
  5. Engeli, S., Feldpausch, M., Gorzelniak, K., Hartwig, F., Heintze, U., Janke, J., Sharma, A. M. (2003). “Association between adiponectin and mediators of inflammation in obese women”. Diabetes52(4), 942-947.
  6. Esmaillzadeh, A., Azadbakht, L. (2008). “Major dietary patterns in relation to general obesity and central adiposity among Iranian women". The Journal of nutrition138(2), 358-363.
  7. Fantuzzi, G. (2008). “Adiponectin and inflammation: consensus and controversy”.Journal of Allergy and Clinical Immunology121(2), 326-330.
  8. Ford, E. S. (2002). “Does exercise reduce inflammation? Physical activity and C-reactive protein among US adults”. Epidemiology13(5), 561-568.
  9. Frühbeck, G., Salvador, J. (2004). “Role of adipocytokines in metabolism and disease”. Nutrition Research24(10), 803-826.
  10. Ghorbani, A., Parastesh, M. (2011). "Relationship between adiponectin and insulin resistance in type II diabetic men after aerobic training". Arak Medical University Journal14(2), 43-50.
  11. Guebre-Egziabher, F., Bernhard, J., Funahashi, T., Hadj-Aissa, A., Fouque, D. (2005). “Adiponectin in chronic kidney disease is related more to metabolic disturbances than to decline in renal function”. Nephrology Dialysis Transplantation20(1), 129-134.
  12. Hamedinia, M., Haghighi, A., Ravasi, A. (2007). “The effect of aerobic training on inflammatory factors. of heart disease in obese men”. Iranian Journal of Harkat34, 47-58.
  13. Hammett, C. J., Prapavessis, H., Baldi, J. C., Varo, N., Schoenbeck, U., Ameratunga, R., Stewart, R. A. (2006). “Effects of exercise training on 5 inflammatory markers associated with cardiovascular risk”. American heart journal151(2), 367-e7.
  14. Hersoug, L. G., Linneberg, A. (2007). “The link between the epidemics of obesity and allergic diseases: does obesity induce decreased immune tolerance?”. Allergy62(10), 1205-1213.
  15. Hoffman, J. (2014). Physiological aspects of sport training and performance. Human Kinetics
  16. Horowitz, J. F., Leone, T. C., Feng, W., Kelly, D. P., Klein, S. (2000). “Effect of endurance training on lipid metabolism in women: a potential role for PPARα in the metabolic response to training”. American Journal of Physiology-Endocrinology And Metabolism279(2), E348-E355.
  17. Jones, L. W., Eves, N. D., Peddle, C. J., Courneya, K. S., Haykowsky, M., Kumar, V., ... Reiman, T. (2009). “Effects of presurgical exercise training on systemic inflammatory markers among patients with malignant lung lesions”.Applied Physiology, Nutrition, and Metabolism34(2), 197-202.
  18. Kahn, C. R. (2000). “Triglycerides and toggling the tummy”. Nature genetics,25(1), 6-7.
  19. Kasapis, C., Thompson, P. D. (2005). “The effects of physical activity on serum C-reactive protein and inflammatory markers”: a systematic review.Journal of the American College of Cardiology45(10), 1563-1569.
  20. Kim, K., Valentine, R. J., Shin, Y., Gong, K. (2008).” Associations of visceral adiposity and exercise participation with C-reactive protein, insulin resistance, and endothelial dysfunction in Korean healthy adults”. Metabolism57(9), 1181-1189.
  21. Kobayashi, J., Murase, Y., Asano, A., Nohara, A., Kawashiri, M. A., Inazu, A., ... Mabuchi, H. (2006).” Effect of walking with a pedometer on serum lipid and adiponectin levels in Japanese middle-aged men”. Journal of atherosclerosis and thrombosis13(4), 197-201.
  22. Koh, E. H., Park, J. Y., Park, H. S., Jeon, M. J., Ryu, J. W., Kim, M., ... Lee, K. U. (2007). “Essential role of mitochondrial function in adiponectin synthesis in adipocytes”. Diabetes56(12), 2973-2981.
  23. Kondo T, Kobayashi I, Murakami M.2006. Effect of exercise on circulating adipokine levels in obese young women. J Endocrinol; 53(2):189-95.
  24. Kraemer, R. R., Castracane, V. D. (2007). “Exercise and humoral mediators of peripheral energy balance: ghrelin and adiponectin”. Experimental biology and medicine232(2), 184-194.
  25. Laughlin, G. A., Barrett-Connor, E., May, S., Langenberg, C. (2007). “Association of adiponectin with coronary heart disease and mortality the rancho bernardo study”. American journal of epidemiology165(2), 164-174.
  26. Lazar, M. A. (2006). “The humoral side of insulin resistance”. Nature medicine,12(1), 43-43.
  27. Leggate, M., Nowell, M. A., Jones, S. A., Nimmo, M. A. (2010). “The response of interleukin-6 and soluble interleukin-6 receptor isoforms following intermittent high intensity and continuous moderate intensity cycling”. Cell stress and Chaperones15(6), 827-833.
  28. Marcell, T. J., McAuley, K. A., Traustadóttir, T., Reaven, P. D. (2005). “Exercise training is not associated with improved levels of C-reactive protein or adiponectin”. Metabolism54(4), 533-541.
  29. Matsushita, K., Yatsuya, H., Tamakoshi, K., Wada, K., Otsuka, R., Zhang, H., ... Toyoshima, H. (2006). “Inverse association between adiponectin and C-reactive protein in substantially healthy Japanese men”. Atherosclerosis188(1), 184-189.
  30. Meyer, A. A., Kundt, G., Lenschow, U., Schuff-Werner, P., Kienast, W. (2006). “Improvement of early vascular changes and cardiovascular risk factors in obese children after a six-month exercise program”. Journal of the American College of Cardiology48(9), 1865-1870.
  31. Moghadasi M, Mohebbi H, Rahmani-Nia F, Hassan-Nia S, Noroozi H, Pirooznia N.(2012)“Highintensity endurance training improves adiponectin mRNA and plasma concentrations”.European journal of applied physiology.; 112(4):1207-1
  32. Murphy, M. H., Murtagh, E. M., Boreham, C. A., Hare, L. G., Nevill, A. M. (2006). “The effect of a worksite based walking programme on cardiovascular risk in previously sedentary civil servants” [NCT00284479]. BMC Public Health6(1), 136.
  33. Olson, T. P., Dengel, D. R., Leon, A. S., Schmitz, K. H. (2007). “Changes in inflammatory biomarkers following one-year of moderate resistance training in overweight women”. International journal of obesity31(6), 996-1003.
  34. Ouchi, N., Kihara, S., Funahashi, T., Nakamura, T., Nishida, M., Kumada, M., ... Matsuzawa, Y. (2003). “Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue”. circulation107(5), 671-674.
  35. Ouchi, N., Walsh, K. (2007). “Adiponectin as an anti-inflammatory factor”.Clinicachimicaacta380(1), 24-30.
  36. Park, E., Shin, M. J., Chung, N. (2007). “The associations between serum leptin, adiponectin and intercellular adhesion molecule-1 in hypercholesterolemic patients”. Nutrition research and practice1(1), 65-69.
  37. Paschos, G. K., Zampelas, A., Panagiotakos, D. B., Katsiougiannis, S., Griffin, B. A., Votteas, V., Skopouli, F. N. (2007). “Effects of flaxseed oil supplementation on plasma adiponectin levels in dyslipidemic men”. European journal of nutrition46(6), 315-320.
  38. Polak, J., Klimcakova, E., Moro, C., Viguerie, N., Berlan, M., Hejnova, J., ... Stich, V. (2006). “Effect of aerobic training on plasma levels and subcutaneous abdominal adipose tissue gene expression of adiponectin, leptin, interleukin 6, and tumor necrosis factor α in obese women”. Metabolism55(10), 1375-1381.
  39. Shavandi N, Saremi A, Ghorbani A, Parastesh M.)2011("Relationship betweenadiponectiand insulin resistance in type II diabetic men after aerobic training". Arak Medical UniversityJournal.;14(2) :4350.[Persian]
  40. Shing, C. M., Webb, J. J., Driller, M. W., Williams, A. D., Fell, J. W. (2013). "Circulating adiponectin concentration and body composition are altered in response to high-intensity interval training". The Journal of Strength & Conditioning Research27(8), 2213-2218.
  41. Sillanpää, P. J., Peltola, E., Mattila, V. M., Kiuru, M., Visuri, T., &Pihlajamäki, H. (2009). Femoral avulsion of the medial patellofemoral ligament after primary traumatic patellar dislocation predicts subsequent instability in men a mean 7-year nonoperative follow-up study. The American journal of sports medicine,37(8), 1513-1521.

 

  1. Simpson, K. A., Singh, M. A. F. (2008). “Effects of exercise on adiponectin: a systematic review”. Obesity16(2), 241-256.
  2. Smith, J., Al-Amri, M., Sniderman, A., Cianflone, K. (2006). "Leptin and adiponectin in relation to body fat percentage, waist to hip ratio and the apoB/apoA1 ratio in Asian Indian and Caucasian men and women". NutrMetab (Lond)3, 18.
  3. Stewart, L. K., Flynn, M. G., Campbell, W. W., Craig, B. A., Robinson, J. P., Timmerman, K. L., ... Talbert, E. (2007). "The influence of exercise training on inflammatory cytokines and C-reactive protein". Medicine and Science in Sports and Exercise39(10), 1714.
  4. Sun, Y., Xun, K., Wang, C., Zhao, H., Bi, H., Chen, X., Wang, Y. (2009). “Adiponectin, an unlocking adipocytokine”. Cardiovascular therapeutics27(1), 59-75.
  5. Talanian, J. L., Galloway, S. D., Heigenhauser, G. J., Bonen, A., Spriet, L. L. (2007). "Two weeks of high-intensity aerobic interval training increases the capacity for fat oxidation during exercise in women". Journal of applied physiology102(4), 1439-1447.
  6. Tchernof, A., Nolan, A., Sites, C. K., Ades, P. A., Poehlman, E. T. (2002). "Weight loss reduces C-reactive protein levels in obese postmenopausal women".Circulation105(5), 564-569.
  7. Tjønna, A. E., Lee, S. J., Rognmo, Ø., Stølen, T. O., Bye, A., Haram, P. M., ... Wisløff, U. (2008). "Aerobic Interval Training Versus Continuous Moderate Exercise as a Treatment for the Metabolic Syndrome A Pilot Study". Circulation,118(4), 346-354.
  8. Toth, P. P. (2005). "Adiponectin and high-density lipoprotein: a metabolic association through thick and thin". European heart journal26(16), 1579-1581.
  9. Trapp, E. G., Chisholm, D. J., Freund, J., Boutcher, S. H. (2008). "The effects of high-intensity intermittent exercise training on fat loss and fasting insulin levels of young women". International journal of obesity32(4), 684-691.
  10. Wang, Z., Nakayama, T. (2010). "Inflammation, a link between obesity and cardiovascular disease". Mediators of inflammation2010.
  11. Watts, K., Jones, T. W., Davis, E. A., Green, D. (2005). "Exercise training in obese children and adolescents". Sports Medicine35(5), 375-392..
  12. Więcek, A., Adamczak, M., Chudek, J. (2007). "Adiponectin—an adipokine with unique metabolic properties". Nephrology Dialysis Transplantation22(4), 981-988.
  13. Winer, J. C., Zern, T. L., Taksali, S. E., Dziura, J., Cali, A. M., Wollschlager, M., ... Caprio, S. (2006). "Adiponectin in childhood and adolescent obesity and its association with inflammatory markers and components of the metabolic syndrome". The Journal of Clinical Endocrinology & Metabolism91(11), 4415-4423.
  14. Yang, Q., Graham, T. E., Mody, N., Preitner, F., Peroni, O. D., Zabolotny, J. M., ... Kahn, B. B. (2005). "Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes". Nature436(7049), 356-362.
  15. YATAGAI, T., NISHIDA, Y., NAGASAKA, S., NAKAMURA, T., TOKUYAMA, K., SHINDO, M., ... ISHIBASHI, S. (2003). "Relationship between exercise training-induced increase in insulin sensitivity and adiponectinemia in healthy men". Endocrine journal50(2), 233-238.
  16. Yudkin, J. S., Kumari, M., Humphries, S. E., Mohamed-Ali, V. (2000). "Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?". Atherosclerosis148(2), 209-214.