Document Type : Research Paper I Open Access I Released under CC BY-NC 4.0 license



The aim of this study was to investigate the effect of 8 weeks of endurance and resistance training on the activity of G4 acetyl cholinesterase in FHL and soleus muscles of rats. 24 male Wistar rats (age: 10 weeks and weight: 171.94±8.961 gr) were randomly divided into 3 groups (control, endurance training (ET) and resistance training (RT)). ET and RT groups carried out 8 weeks (5 sessions per week) of training programs. Resistancetraining included climbing a 1-m ladder (26 stairs) carrying a weight.Results showed that the activity of this protein in fast twitch muscle of RT and ET groups increased significantly (P=0.045 and P=0.015 respectively) compared to control group, but there were no significant differences between RT and ET groups in the mean activity of this protein in the fast twitch muscle (P=0.838). Activity of this protein in slow muscle of RT group was significantly higher than control and ET group (P=0.003 and P=0.005 respectively) but there were no significant differences between control and ET groups in the mean activity of this protein (P=0.958). It seems that this resistance training protocol had a clear effect on the G4 AChE activity in both slow and fast twitch muscles, suggesting the importance of this type of training for adaptations of these muscles. Response to both types of training by fast twitch muscles could be due to more responsiveness of these muscles to training stimuli. 


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