Sport Biosciences

The Effect of Endurance Swimming Training on Lung VEGF Level in Pregnant Rats Exposed to Cadmium Poisoning

Document Type : Research Paper

Authors

Shadmehr Mirdar 1
Isa Mahdinia
Tahereh Bayani 2

1 Associate Professor University of Mazandaran

2 teacher

https://doi.org/10.22059/jsb.2016.59093
Abstract
The aim of this study was to investigate the effect of a period of swimming training on lung VEGF level in pregnant rats exposed to cadmium poisoning. 32 female Wistar rats were acclimatized with a new environment and water for 2 weeks; then, they had pregnancy and were divided into swimming, cadmium, cadmium - swimming and control groups. Swimming training started from the first day of pregnancy and it lasted 60 min./day in the second week of pregnancy. Samples of lung tissue were collected two days after delivery. Lung VEGF was determined by ELISA method. The data were analyzed by one-way analysis of variance and Tukey post hoc test at significance level of P≤0.05. Results showed that lung VEGF significantly decreased after delivery in cadmium group compared with the control group (P≤0.001). The difference of lung VEGF was not significant between swimming and control groups, but lung VEGF in cadmium - swimming group was significantly higher than cadmium group (P≤0.001). As cadmium inhibits lung angiogenesis activity during pregnancy, swimming can be beneficial to maintain the level of VEGF as a marker of angiogenesis.


 

Keywords

Cadmium
pregnancy
swimming
VEGF
Sport Biosciences
Volume 8, Issue 2
Summer 2016
Pages 177-191

  • Receive Date 23 April 2014
  • Revise Date 22 January 2015
  • Accept Date 22 January 2015

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