Document Type : Research Paper I Open Access I Released under CC BY 4.0 license
Dept. of Sport Physiology, School of Physical Education And Sport Science, Shiraz University, Shiraz, Iran.
Department of Exercise Physiology, Tehran University, Tehran, Iran
The aim of the present study was to investigate the effect of HIIT run on PGC-1α gene expression in fast & slow twitch muscles of healthy male rats. For this purpose, 12 male Wistar rats divided into two groups: contorol (n=6) and exercise (n=6) , respectively. Intense interval training was consists of five days and a total of eight weeks, that was formed the three frequencies ( 90 to 100% VO2max intensity for four minutes and two minutes at an intensity of 50 to 60% VO2max). 24 hours after the last training session, extensor digitorum longus muscle (EDL) and soleus was extracted and relevant variables and expression levels were measured by RT-PCR. Results showed a HIIT run a significant increase PGC-1α gene expression in both muscle groups were trained (p=0/004 and p=0/001). According to the findings, implement HIIT will be increases PGC-1α and oxidative capacity in SOL and EDL muscles.