Document Type : Research Paper I Open Access I Released under CC BY-NC 4.0 license


1 Associate professor of sport physiology, Physical education and sport science faculty, Ferdowsi University of Mashhad, Mashhad, Iran

2 PhDStudent of sport physiology, physical education and sport science faculty, Ferdowsi University of Mashhad, Mashhad, Iran

3 PhD Student of sport physiology, physical education and sport science faculty, FerdowsiUniversity of Mashhad, Mashhad, Iran


Introduction: we researched to study the Effect of Berberis vulgaris supplementation on glycemic indices patients with diabetes type 2 after one session of aerobic exercise in accordance to independent effects of barberry extract and aerobic exercise.
Methods and material: 32 patient men with type 2 diabetes accidently divided into four groups of barberry extract (10 cc per 200 ml of water), exercise (60 to 70 of maxHR), combination of exercise and barberry extract and control. Glycemic indices were measured at the initiation of protocol and once at the end. Paired T test and ANOVA were used for data analysis.
Results: the following variable were reduced at the end in comparison to the primary assessment: serum glucose (barberry extract, exercise training and combination), glucolized hemoglobin (combination), insulin (exercise training and combination), insulin resistance (barberry extract, exercise training and combination)(P<0.05). Also the following variables are lower in comparison to control: serum glucose (combination), insulin (exercise training and combination), insulin resistance (combination) (P<0.05).
Conclusion: aerobic exercise and extract of barberry have independent beneficial effects on glycemic indices. However utilization of the both can amplify the effects to improve diabetes type2.
Keywords: Insulin, Type diabetes, Berberis vulgaris, Glucose, Insulin resistance, Aerobic exercise, Gelycolized hemoglobin.


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