Document Type : Research Paper I Open Access I Released under CC BY-NC 4.0 license


1 M.Sc. Student in Exercise Physiology, University of Sistan & Baluchestan, Zahedan, Iran

2 . Associate Professor in Exercise Physiology, Department of Physical Education and Sport Sciences, University of Sistan & Baluchestan, Zahedan, Iran


This research aims at the effect of two methods of endurance and resistance training on plasma levels Apelin and some anthropometric variables of overweight and obese girls. 34 individual (kg/m2 25


1. محمدی دمیه، امین، خواجه لندی، علی، رستمی، افشین، اسدی، عزت‌الله. (1389). "مقایسۀ اثرات 8 هفته تمرین قدرتی و استقامتی بر سطوح ویسفاتین پلاسمای مردان میان سال". مجلۀ ارمغان دانش، دورۀ 15، شمارۀ 3، صص 242-233.
2. مقرنسی، مهدی، باقری، میترا. (1392). " اثر دوازده هفته تمرین مقاومتی دایره‌ای بر پروتئین واکنشگر C و نیمرخ لیپیدی زنان غیرفعال". نشریۀ علوم زیستی ورزشی، دورۀ 6، شمارۀ 2، صص 244-233.

3. وکیلی، جواد، رواسی، علی‌اصغر، گائینی، عباسعلی. (1388). "بررسی اثر تداخلی تمرینات ترکیبی (قدرتی و استقامتی همزمان) بر قدرت و توان هوازی بیشینه". نشریۀ علوم زیستی ورزشی، دورۀ 1، شمارۀ 3، صص 55-41.

4. Abdel-lateif, D. M., & El-Shaer, S. S. (2012). “Association between changes in serum vaspin concentrations and changes of anthropometric and metabolic variables in obese subjects after weight reduction”. Journal of American Science., Vol.8, No. 4, PP: 606-611.
5. Ayatollahi, S., Ghoreshizadeh, Z. ) 2010(.“ Prevalence of obesity and overweight among adults in Iran”.Obesity reviews., Vol. 11, No.5, PP: 335-7.
6. Beavers, K.M., Brinkley, T.E., Nicklas, B.J. (2010). “Effect of exercise training on chronic inflammation”. Clinica Chimica Acta., Vol. 411, No. 3, PP: 785–793.
7. Blüher M. (2009). “Adipose tissue dysfunction in obesity”. Exp Clin Endocrinol Diabetes., Vol. 117, No. 6, PP: 241–50.
8. Bouassida, A., Chamari, K., Zaouali, M., Feki, Y., Zbidi, A., Tabka, Z. (2010). “Review on leptin and adiponectin responses and adaptations to acute and chronic exercise”. British journal of sports medicine., Vol. 44, No. 9, PP: 620-30.
9. Boucher, J., Masri, B. (2005).“Apelin, a Newly Identified Adipokine Up-Regulated by”. Insulin and Obesity, Endocrinology., Vol. 146, No. 4, PP: 1764-1771.
10. Brzycki, M. (1993). “A practical approach to strength training”. 1st ed. McGraw Hill.Womens sports fitness., Vol. 268, No. 8, PP:5457-63.
11. Castan-Laurell, I., Michaela, V., Danièle, D., Cédric, D., Michaela, K., Zuzana, K., et al. (2008). “Effect of Hypocaloric Diet-Induce Weight Loss in Obese Women On Plasma Apelin And Adipose Tissue Expression or Apelin and APJ”. Eur J Endocrinol., Vol. 158, No. 6, PP: 905-910.
12. Chandrasekaran, B., Dar, O., McDonagh, T. (2008). “ The role of apelin in cardiovascular function and heart failure”. European Journal of HeartFailure., Vol. 10, No. 8, PP: 725–732.
13. Chatzinikolaou, A., Fatouros, I., Petridou, A., Jamurtas, A., Avloniti, A., Douroudos, I., et al. (2008). “Adipose tissue lipolysis is upregulated in lean and obese men during acute resistance exercise”. Diabetes Care., Vol. 31, No. 7, PP: 1397-9.
14. Cho, JK., Han, TK., Kang, HS. (2010). “Combined effects of body mass index and cardio/respiratory fitness on serum vaspin concentrations in Korean young men”. Eur J Appl Physiol., Vol. 108, No.2, PP: 347-353.
15. Eldor, R., Raz, I. (2006). “Lipotoxicity versus adipotoxicity—the deleterious effects of adipose tissue on beta cells in the pathogenesis of type 2 diabetes”. Diabetes research andclinical practice., Vol. 74, No. 2, PP: S3-S8.
16. Fatouros, I. G., Chatzinikolaou, A., Tournis, S., Nikolaidis, M. G., Jamurtas, A. Z., Douroudos, I. I., et al. (2009).“ Intensity of resistance exercise determines adipokine and resting energy expenditure responses in overweight elderly individuals”. Diabetes care., Vol. 32, No. 12, PP: 2161-7.
17. Foldes, G., Horkay, F., Szokodi, I., Vuolteenaho, O., Ilves, M., Lindstedt, KA., et al. (2003).“ Circulating and Cardiac Levels of Apelin, the Novel Ligand of the Orphan Receptor APJ, in Patients with Heart Failure”. Biochem Biophys Res Commun., Vol. 308, No. 3, PP: 480-5.
18. Hassanzadeh, J., Mohammadbeigi, A., Eshrati, B., Moemenbellah- Fard, MD. (2012). “ Estimation of the regional burden of noncommunicable diseases due to obesity and overweight in Mark-azi province, Iran, 2006-2007”. J Cardiovasc Dis Res., Vol. 3, No. 1, PP: 26-31.
19. Heinonen, MV., Laaksonen, DE., Karhu, T., Karhunen, L., Laitinen, T., Kainulainen, S., et al. (2009). “Effect of diet-induced weight loss on plasma apelin and cytokine levels in individuals with the metabolic syndrome”. Nutr Metab Cardiovas., Vol. 19, No. 9, PP: 626-33.
20. Heinonen, MV., Purhonen, AK., Miettinen, P., et al. (2005). “Apelin, orexin-A and leptin plasma levels in morbid obesity and effect of gastric banding”. Regul Pept.,Vol. 130, No. 1-2, PP: 7-13.
21. Jackson, AS., Pollock, ML., Ward, A. (1980). “Generalized equations for predicting body density of women”. Med Sci Sports Exerc., Vol. 12, No. 3, PP: 175-181.
22. Kadoglou, NP., Vrabas, IS., Kapelouzou, A., Lampropoulos, S., Sailer, N., Kostakis, A., (2012). “The impact of aerobic exercise training on novel adipokines, apelin and ghrelin, in patients with type 2 diabetes”. Med Sci Monit., Vol.18, No.5, PP: 290-295.
23. Kalea, AZ., Batlle, D. (2010). “Apelin and ACE2 in cardiovascular disease”. Curr Opin Investig Drugs., Vol. 11, No. 3, PP: 273-82.
24. Kang, J., Rashti, S. L., Tranchina, C. P., Ratamess, N. A., Faigenbaum, A. D., and Hoffman, J. R. (2009). “Effect of preceding resistance exercise on metabolism during subsequent aerobic session”. Eur J Appl Physiol. 107:PP: 43-50.
25. Kopf, S. (2011). “Circuit training basics and benefits”. National Academy of Sports Medicine Certified Personal Trainer.
26. La Vecchia, C., Giordano, SH., Hortobagyi, GN., Chabner, B. (2011). “Overweight, obesity, diabetes, and risk of breast cancer: interlocking pieces of the puzzle”. Oncologist., Vol. 16, No. 6, PP: 726-9.
27. Meral, C., Tascilar, E., Karademir, F., Tanju, IS., Cekmez, F., Ipcioglu, OM., (2010). “Elevated Plasma Levels of Apelin in Children with Type 1 Diabetes Mellitus”. J Pediatr Endocrinol Metab., Vol. 23, No. 5, PP: 497-502.
28. Organization WH.(2006). Fact sheet: “obesity and overweight”. Internet: http://www who int/dietphysicalactivity/publications/facts/obesit y/en/(accessed 3 January 2005).
29. Poehlman, ET., Dvorak, RV., DeNino, WF., Brochu, M., Ades, PA. (2000). “Effects of resistance training and endurance training on insulin sensitivity in nonobese, young women: a controlled randomized trial”. J Clin Endocrinol Metab., Vol. 85, No.(7), PP: 2463-8.
30. Ringström, C., Nitert, MD., Bennet, H., Fex, M., Valet, P., Rehfeld, JF., (2010). “Apelin is a novel islet peptide”. Regul Pept., Vol. 162, No. 1-3, PP: 44-51.
31. Sell, H., Eckel, J.(2010). “Adipose tissue inflammation: novel insight into the role of macrophages and lymphocytes”. Curr Opin Clin Nutr Metab Care., Vol. 13, No. 4, PP: 366- 70.
32. Sheibani, SH., Hanachi, P., Refahiat, MA. (2012). “Effect of aerobic exercise on
serum concentration of apelin, TNFα and insulin in obese women”. Iran J Basic Med Sci., Vol. 15, NO. 6, PP: 1196-201.
33. Soriguer, F., Garrido, L., Garcia-Serrano, S., Garcia-Almeida, JM., Garcia-Arnes, J., Tinahones, FJ., et al. (2009). “Apelin levels are increased in morbidly obese subjects with type 2 diabetes mellitus”. Obes Surg., Vol. 19, No.11, PP: 1574-1580.
34. Tapan, S., Tascilar, E., Abaci, A., Sonmez, A., Kilic, S., Erbil, MK., (2010). “Decreased plasma apelin levels in pubertal obese children”. J Pediatr Endocrinol Metab.,Vol. 23, No. 10, PP: 1039-1046.
35. Ting, SM., Nair, H., Ching, I., Taheri, S., Dasgupta, I. (2009). “Overweight, obesity and chronic kidney disease”. Nephron Clin Pract., Vol.112, No. 3, PP: c121-7; discussion c127.
36. Wright, D., Sutherland, L. (2009). “Exercise Increases Apelin Expression in White Adipose Tissue”. Medicine & Science in Sports & Exercise., Vol. 41, No. 5, PP: 38.
37. Yue, P., Jin, H., Aillaud, M., Deng, AC., Azuma, J., Asagami, T., et al. (2010). “Apelin is necessary for the maintenance of insulin sensitivity”. Am J Physiol Endocrinol Metab., Vol. 298, No. 1, PP: 59-67.
38. Zhou, L., Yu, X., Meng, Q., Li, H., Niu, C., Jiang, Y., et al. (2013). “Resistin reduces mitochondria and induces hepatic steatosis in mice by the protein kinase C/protein kinase G/p65/PPAR gamma coactivator 1 alpha pathway”. Hepatology., Vol. 57, No. 4, PP: 1384-93.
39. Ziccardi P, Nappo F, Giugliano G, Esposito K, Marfella R, Cioffi M, et al. Reducing of inflammatory cytokine concentration and improvement of endothelial functions in obese women after weight loss over on year.Circulation. 2002;105 :804-809.