The purpose of this research was to determine the effects of intermittent and continuous training on inflammatory factors of CRP and fibrinogen of young obese females. For this purpose, 36 obese sedentary subjects (body mass index>30) were randomly selected and randomly assigned to 3 groups of 12 subjects :intermittent training, continuous training and control (mean and SD of height, weight, age 163.2±5.8 cm, 86.8±11.8 kg, 20.7±1.3 years; 160.2±6.4 cm, 83.8±9.5 kg, 22.1±2.2 years; 166.2±7.1 cm, 86.6±10.5 kg, 22±2.4 years, respectively). The intermittent group participated in an 800-meter (4 x 200m run = 800m) exercise with 80%-90% of maximal reserved heart rate and 1/3 rest interval. A distance of 400 meters (2 x 200m) was added to the primary distance every week. The continuous group ran this distance (800 m) with 60%-70% of maximal reserved heart rate with 400 meters added to the primary distance weekly. The control group received no intervention. Before and after the protocol, fibrinogen and CRP were recorded and measured. One-way analysis of variance, LSD post hoc test and paired t tests were used to determine the effects of both types of exercises (α=0.05). The intr-group results showed a significant decrease in fibrinogen in the continuous group (P=0.005). The intera-group results revealed a significant change of CRP between the intermittent and continuous groups (P=0.04) and also between the intermittent and the control groups (P=0.001). In addition, there was a significant change of in fibrinogen between the intermittent and control groups (P=0.006). It seems that both types of exercise had positive effects on CRP and fibrinogen levels.