The aim of this study was to determine the effects of circuit resistance training with different intensities on plasma ghrelin and GH in non–athlete young women. For this purpose, 20 young women were voluntarily selected and randomly divided into four experimental and control groups. Experimental groups were three groups who performed the protocol with intensity of 40% 1RM (group 1), %60 1RM (group 2) and %80 1RM (group 3) while control group remained sedentary. Blood samples were collected before and immediately after the exercise. Data were analyzed using paired sample t test, one-way ANOVA and Pearson correlation coefficient (P?0.05). The results showed an increase in plasma ghrelin in all three intensities (P<0.05) and in group 2, ghrelin increased more than other groups (P<0.001). In three experimental groups, GH increased (P<0.05) while this increase was more in group 3 than other groups (P<0.001). There was no significant relationship between GH and ghrelin in any intensities (P=0.719). It can be concluded that the increase of ghrelin may be attributed to the response to the negative balance induced by intense resistance training. Also, an increase in ghrelin is not directly dependent on the intensity of training.