The purpose of this study was to investigate the effects of short term creatine monohydrate as an ergogenic supplement on the sprint performance and muscular strength of wrestlers. 20 wrestlers were selected randomly and divided into two groups. One group was placebo group (control) and the other group was creatine supplement group (experimental). In a double blind project, subjects' speed running, perseverance in repeated alternative speeds and muscular strength (with 1-RM in knee extension) were measured before creatine and placebo as pretest, and after that as posttest. Creatine and placebo were used for 7 days (20 grams creatine monohydrate per day by experimental group and 20 (g/d) dextrose polymer as placebo by control group).The data were analyzed by correlated t – test (for each group) and independent t-test (between two groups). The results showed that short term use of creatine supplement had a significant effect on short term running (20 and 40 meters), long term running (60 and 100 meters), interval speed endurance running (30 fast running in 5 seconds with 10 seconds of rest between each running) and muscle strength (1-RM in knee extension) of wrestlers (p<0.05).