Document Type : Research Paper I Open Access I Released under CC BY-NC 4.0 license
Authors
1 Department of Sport Sciences, Faculty of Humanities and Educational Sciences, Tabriz Branch, Islamic Azad University, Tabriz
2 Department of Physical Education & Sport Sciences, Faculty of Humanities & Education, Tabriz Branch, Islamic Azad University, Tabriz, Iran
3 Department of exercise physiology, Faculty of Physical Education and Sports Sciences, University of Tabriz, Tabriz
Abstract
Introduction: The aim of this study was to determine the effect of HIIT with coenzyme Q10 supplementation on BMP-6 growth in obese male rats. Therefore, the aim of this study was to determine the effect of HIIT along with coenzyme Q10 supplementation on BMP-6 growth in obese male rats.
Methods: 30 male Wistar rats were randomly divided into 6 groups including 1) lean reference, 2) obese reference, 3) obese control, 4) obese supplement, 5) obese exercise and 6) exercise+obese supplement. The lean reference and obese reference groups were sacrificed at the beginning of the study. The training groups underwent HIIT program for 12 weeks. 500 mg/kg of coenzyme Q10 supplement was gavage to the rats of the supplemented groups. BMP-6 levels in blood were measured using ELISA method. The data was analyzed using one-way analysis of variance.
Results: The values of BMP-6 decreased in the obese training group compared to the lean reference group (p<0.001) and increased compared to the obese control group (p=0.032), decreased in the obese supplement group compared to the lean reference group(p<0.001), and significantly decreased in the exercise+obese supplement group compared to the lean reference group (p<0.001). However, no significant difference was observed between the three obese supplement groups, obese reference and obese control(p>0.05).
Conclusion: 12 weeks of HIIT leads to a significant increase in BMP-6 levels in obese samples. However, the administration of coenzyme Q10 alone or together with HIIT for 12 weeks does not lead to a significant increase in BMP-6 levels.
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