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The Effect of 8-week High Intensity Interval Training on Intima-Media Thickness of Central and Peripheral Arteries in Overweight Men

Document Type : Research Paper I Open Access I Released under CC BY-NC 4.0 license

Authors

1 PhD student of exercise physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran

2 Assistant professor of exercise physiology, Sport Sciences Group, Khavaran Institute of Higher Education, Mashhad, Iran

3 Associate professor of exercise physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran

Abstract

The assessment of Intima-Media Thickness (IMT) is a crucial tool for primary prediction of atherosclerosis. The purpose of the study was to determine the effect of 8-week high intensity interval training on intima-media thickness of central and peripheral arteries in overweight men. Present research was quasi-experimental design. Subjects were 18 overweight men (mean BMI 27.9 ± 4.2 Kg/m2). Follow participant election, maximum oxygen consumption test was performed and they were randomly divided into two HIIT (n=12) and control (n=6) groups. Body composition (were evaluate by bio-impedance system), carotid and femoral intima-media thicknesses (FIMT) (were evaluate by ultrasonic system and B-Mode method), and VO2peak assessments were performed in pre- and post-test occasions. All data analysis were done by Two way ANOVA at p<0.05. Body fat percent of subjects were significantly decreased in HIIT group (p=0.041). Also, FIMT were significantly decreased in people with IMT less than 0.9 mm (p=0.026). The study illustrated that IMT of central and peripheral arteries subsequent of 8 weeks HIIT were decreased in overweight men. Also, it is probable that HIIT has an ability to decrease IMT only in overweight men with IMT less than 0.9 mm.

Keywords

Main Subjects

References

  1.  

    1. Thijssen DH, Cable NT, Green DJ. Impact of exercise training on arterial wall thickness in humans. Clinical science. 2012;122(7):311-22.
    2. de Groot E, Hovingh GK, Wiegman A, Duriez P, Smit AJ, Fruchart J-C, et al. Measurement of arterial wall thickness as a surrogate marker for atherosclerosis. Circulation. 2004;109(23 suppl 1):III-33-III-8.
    3. Chambless LE, Shahar E, Sharrett AR, Heiss G, Wijnberg L, Paton CC, et al. Association of transient ischemic attack/stroke symptoms assessed by standardized questionnaire and algorithm with cerebrovascular risk factors and carotid artery wall thickness: The ARIC study, 1987–1989. American journal of epidemiology. 1996;144(9):857-66.
    4. Lim TK, Lim E, Dwivedi G, Kooner J, Senior R. Normal Value of Carotid Intima-Media Thickness–A Surrogate Marker of Atherosclersosis: Quantitative Assessment by B-Mode Carotid Ultrasound. Journal of the American Society of Echocardiography. 2008;21(2):112-6.
    5. Kota SK, Mahapatra GB, Kota SK, Naveed S, Tripathy PR, Jammula S, et al. Carotid intima media thickness in type 2 diabetes mellitus with ischemic stroke. Indian journal of endocrinology and metabolism. 2013;17(4):716.
    6. Mitu F, Mitu M, Turiceanu M, Caliap TA, Leatu CG. [The importance of carotid ultrasound in the risk stratification of patients with ischaemic heart disease]. Rev Med Chir Soc Med Nat Iasi. 2008;112(2):337-42.
    7. Mateo I, Morillas P, Quiles J, Castillo J, Andrade H, Roldأ،n J, et al. What measure of carotid wall thickening is the best atherosclerotic loading score in the hypertensive patient: maximum or mean value? Revista Espaأ±ola de Cardiologأa (English Edition). 2011;64(5):417-20.
    8. Rosfors S, Hallerstam S, Jensen-Urstad K, Zetterling M, Carlstrأ¶m C. Relationship between intima-media thickness in the common carotid artery and atherosclerosis in the carotid bifurcation. Stroke. 1998;29(7):1378-82.
    9. Lemne C, Jogestrand T, de Faire U. Carotid intima-media thickness and plaque in borderline hypertension. Stroke. 1995;26(1):34-9.
    10. Gaesser GA, Angadi SS. High-intensity interval training for health and fitness: can less be more? Journal of Applied Physiology. 2011;111(6):1540-1.
    11. Troiano RP, Berrigan D, Dodd KW, Masse LC, Tilert T, McDowell M. Physical activity in the United States measured by accelerometer. Medicine and science in sports and exercise. 2008;40(1):181.
    12. Little JP, Gillen JB, Percival ME, Safdar A, Tarnopolsky MA, Punthakee Z, et al. Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes. Journal of Applied Physiology. 2011;111(6):1554-60.
    13. Rognmo أ, Hetland E, Helgerud J, Hoff J, Slأ¸rdahl SA. High intensity aerobic interval exercise is superior to moderate intensity exercise for increasing aerobic capacity in patients with coronary artery disease. European Journal of Cardiovascular Prevention & Rehabilitation. 2004;11(3):216-22.
    14. Thijssen DH, Cable NT, Green DJ. Impact of exercise training on arterial wall thickness in humans. Clinical science. 2012;122(7):311-22.

    15.de Groot E, Hovingh GK, Wiegman A, Duriez P, Smit AJ, Fruchart J-C, et al. Measurement of arterial wall thickness as a surrogate marker for atherosclerosis. Circulation. 2004;109(23 suppl 1):III-33-III-8.

    16.Chambless LE, Shahar E, Sharrett AR, Heiss G, Wijnberg L, Paton CC, et al. Association of transient ischemic attack/stroke symptoms assessed by standardized questionnaire and algorithm with cerebrovascular risk factors and carotid artery wall thickness: The ARIC study, 1987–1989. American journal of epidemiology. 1996;144(9):857-66.

    17.Lim TK, Lim E, Dwivedi G, Kooner J, Senior R. Normal Value of Carotid Intima-Media Thickness–A Surrogate Marker of Atherosclersosis: Quantitative Assessment by B-Mode Carotid Ultrasound. Journal of the American Society of Echocardiography. 2008;21(2):112-6.

    18.Kota SK, Mahapatra GB, Kota SK, Naveed S, Tripathy PR, Jammula S, et al. Carotid intima media thickness in type 2 diabetes mellitus with ischemic stroke. Indian journal of endocrinology and metabolism. 2013;17(4):716.

    19.Mitu F, Mitu M, Turiceanu M, Caliap TA, Leatu CG. [The importance of carotid ultrasound in the risk stratification of patients with ischaemic heart disease]. Rev Med Chir Soc Med Nat Iasi. 2008;112(2):337-42.

    20.Mateo I, Morillas P, Quiles J, Castillo J, Andrade H, Roldأ،n J, et al. What measure of carotid wall thickening is the best atherosclerotic loading score in the hypertensive patient: maximum or mean value? Revista Espaأ±ola de Cardiologأa (English Edition). 2011;64(5):417-20.

    21.Rosfors S, Hallerstam S, Jensen-Urstad K, Zetterling M, Carlstrأ¶m C. Relationship between intima-media thickness in the common carotid artery and atherosclerosis in the carotid bifurcation. Stroke. 1998;29(7):1378-82.

    22.Lemne C, Jogestrand T, de Faire U. Carotid intima-media thickness and plaque in borderline hypertension. Stroke. 1995;26(1):34-9.

    1. Gaesser GA, Angadi SS. High-intensity interval training for health and fitness: can less be more? Journal of Applied Physiology. 2011;111(6):1540-1.
    2. Troiano RP, Berrigan D, Dodd KW, Masse LC, Tilert T, McDowell M. Physical activity in the United States measured by accelerometer. Medicine and science in sports and exercise. 2008;40(1):181.
    3. Little JP, Gillen JB, Percival ME, Safdar A, Tarnopolsky MA, Punthakee Z, et al. Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes. Journal of Applied Physiology. 2011;111(6):1554-60.
    4. Rognmo أ, Hetland E, Helgerud J, Hoff J, Slأ¸rdahl SA. High intensity aerobic interval exercise is superior to moderate intensity exercise for increasing aerobic capacity in patients with coronary artery disease. European Journal of Cardiovascular Prevention & Rehabilitation. 2004;11(3):216-22.
    5. Trapp E, Chisholm D, Freund J, Boutcher S. The effects of high-intensity intermittent exercise training on fat loss and fasting insulin levels of young women. International journal of obesity. 2008;32(4):684-91.
    6. Lavie CJ, Arena R, Earnest CP. High-intensity interval training in patients with cardiovascular diseases and heart transplantation. J Heart Lung Transplant. 2013;32(11):1056-8.
    7. Kemi OJ, Wisloff U. High-Intensity aerobic exercise training improves the heart in health and disease. Journal of Cardiopulmonary Rehabilitation and Prevention. 2010;30(1):2-11.
    8. Khodadadi H, Rajabi H, Seyyed Reza Attarzadeh SR, Abbasian S. The Effect of High Intensity Interval Training (HIIT) and Pilates on Levels of Irisin and Insulin Resistance in Overweight Women. Iranian Journal of Endocrinology and Metabolism. 2014;16(3):190-6.
    9. Byrkjeland R, Stensaeth K-H, Anderssen S, Njerve IU, Arnesen H, Seljeflot I, et al. Effects of exercise training on carotid intima-media thickness in patients with type 2 diabetes and coronary artery disease. Influence of carotid plaques. Cardiovascular Diabetology. 2016;15(1):13.
    10. Benda NM, Seeger JP, Stevens GG, Hijmans-Kersten BT, van Dijk AP, Bellersen L, et al. Effects of High-Intensity Interval Training versus Continuous Training on Physical Fitness, Cardiovascular Function and Quality of Life in Heart Failure Patients. PloS one. 2015;10(10):e0141256.
    11. Farpour-Lambert NJ, Aggoun Y, Marchand LM, Martin XE, Herrmann FoR, Beghetti M. Physical activity reduces systemic blood pressure and improves early markers of atherosclerosis in pre-pubertal obese children. Journal of the American College of Cardiology. 2009;54(25):2396-406.
    12. Meyer AA, Kundt Gn, Lenschow U, Schuff-Werner P, Kienast W. Improvement of early vascular changes and cardiovascular risk factors in obese children after a six-month exercise program. Journal of the American College of Cardiology. 2006;48(9):1865-70.
    13. Woo KS, Chook P, Chung WY, Sung RY, Qiao M, Leung SS, et al. Effects of diet and exercise on obesity-related vascular dysfunction in children. Circulation. 2004;109(16):1981-6.
    14. Baecke J, Burema J, Frijters J. A short questionnaire for the measurement of habitual physical activity in epidemiological studies. The American journal of clinical nutrition. 1982;36(5):936-42.
    15. Potischman N, Carroll RJ, Iturria SJ, Mittl B, Curtin J, Thompson FE, et al. Comparison of the 60-and 100-item NCI-block questionnaires with validation data. Nutrition and cancer. 1999;34(1):70-5.
    16. Dupont G, Akakpo K, Berthoin S. The effect of in-season, high-intensity interval training in soccer players. J Strength Cond Res. 2004;18(3):584-9.
    17. Rognmo أ, Moholdt T, Bakken H, Hole T, Molstad P, Myhr NE, et al. Cardiovascular risk of high-versus moderate-intensity aerobic exercise in coronary heart disease patients. Circulation. 2010;126(12):1436-40.
    18. Rognmo O, Hetland E, Helgerud J, Hoff J, Slerdahl SA. High intensity aerobic interval exercise is superior to moderate intensity exercise for increasing aerobic capacity in patients with coronary artery disease. European Journal of Cardiovascular Prevention & Rehabilitation. 2004;11(3):216-22.
    19. Pignoli P, Tremoli E, Poli A, Oreste P, Paoletti R. Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging. Circulation. 1986;74(6):1399-406.
    20. Salgado AL, Carvalho L, Oliveira AC, Santos VN, Vieira JG, Parise ER. Insulin resistance index (HOMA-IR) in the differentiation of patients with non-alcoholic fatty liver disease and healthy individuals. Arq Gastroenterol. 2010;47(2):165-9.
    21. Lorenz MW, Schaefer C, Steinmetz H, Sitzer M. Is carotid intima media thickness useful for individual prediction of cardiovascular risk? Ten-year results from the Carotid Atherosclerosis Progression Study (CAPS). European heart journal. 2010;31(16):2041-8.
    22. Maiorana AJ, Naylor LH, Exterkate A, Swart A, Thijssen DH, Lam K, et al. The impact of exercise training on conduit artery wall thickness and remodeling in chronic heart failure patients. Hypertension. 2011;57(1):56-62.
    23. Okada K, Maeda N, Tatsukawa M, Shimizu C, Sawayama Y, Hayashi J. The influence of lifestyle modification on carotid artery intima-media thickness in a suburban Japanese population. Atherosclerosis. 2004;173(2):327-35.
    24. Jae SY, Carnethon MR, Heffernan KS, Choi Y-H, Lee M-K, Fernhall B. Association between cardiorespiratory fitness and prevalence of carotid atherosclerosis among men with hypertension. American heart journal. 2007;153(6):1001-5.
    25. Langille BL, O'Donnell F. Reductions in arterial diameter produced by chronic decreases in blood flow are endothelium-dependent. Science. 1986;231(4736):405-7.
    26. Ku DN, Giddens DP, Zarins CK, Glagov S. Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low oscillating shear stress. Arteriosclerosis, thrombosis, and vascular biology. 1985;5(3):293-302.
    27. Rowley NJ, Dawson EA, Birk GK, Cable NT, George K, Whyte G, et al. Exercise and arterial adaptation in humans: uncoupling localized and systemic effects. Journal of Applied Physiology. 2011;110(5):1190-5.
    28. Thijssen DH, Dawson EA, van den Munckhof IC, Tinken TM, Den Drijver E, Hopkins N, et al. Exercise-mediated changes in conduit artery wall thickness in humans: role of shear stress. American Journal of Physiology-Heart and Circulatory Physiology. 2011;301(1):H241-H6.
    29. Lovren F, Teoh H, Verma S. Obesity and atherosclerosis: mechanistic insights. Canadian Journal of Cardiology. 2015;31(2):177-83.
Journal of Sport Biosciences
Volume 13, Issue 3
November 2021
Pages 267-283
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History
  • Receive Date: 13 May 2016
  • Revise Date: 22 November 2021
  • Accept Date: 25 July 2016
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