University of Tehran Journal of Sport Biosciences 2008-9325 14 1 2022 04 21 The Effects of Eight Weeks Circuit Resistance Training on Interleukin-1β, TNF-α and Blood Pressure in pre-Hypertensive Obese Women. The Effects of Eight Weeks Circuit Resistance Training on Interleukin-1β, TNF-α and Blood Pressure in pre-Hypertensive Obese Women. 67 84 88153 10.22059/jsb.2022.329658.1484 FA Hengameh Moradian PhD candidate of Exercise Physiology, Faculty of physical education, Kermanshah branch, Islamic Azad University, Kermanshah, Iran Sedigheh Hossein Pour Delavar Assistant professor, Exercise Physiology, Faculty of Sports Sciences, Kermanshah branch, Islamic Azad University, Kermanshah , Iran Ali Zabet Assistant professor, Exercise Physiology, Faculty of Sports Sciences, Kangavar branch, Islamic Azad University, Kermanshah, Iran Journal Article 2021 08 29 The aim of this study was to investigate the effects of eight weeks Circuit Resistance Training (CRT) on some inflammatory cytokines, blood pressure and insulin resistance in pre-hypertensive obese women. For this purpose, 24 pre-hypertensive obese women (mean age: 44.73±4.43 years, body mass index: 32.39±3.8 kg/m², systolic: 13.21±0.61 mmHg and diastolic: 8.65±0.33 mmHg blood pressure levels), were conveniently selected and randomly divided into CRT training (n=12) and Control (n=12) groups. The intervention consisted of 8 weeks of circuit resistance training, with a frequency of 3 sessions per week, and each session lasted 50 to 60 minutes (15 minutes of warm-up, 30 minutes of weight training, and 10 minutes of cooling). Resistance trainings were performed with an intensity of 40% 1RM for upper body and 60% 1RM for lower body movements. Measurements and blood sampling were done pre and post 8 weeks of training. Data were analyzed using Shapiro-Wilks and analysis of variance with a 2×2 design at a significance level of p˂0.05. The results showed that 8 weeks of CRT have significant effects on body fat percent (p=0.007), Waist to Hip Ratio (p=0.017), systolic (p<0.0005) and diastolic (p=0.016) blood pressure and insulin resistance (p=0.043). However, it was not significant in the inflammatory cytokines IL-1β and TNF-α (P ≤ 0.05). The reason could be the type of exercise selected. Depending on the intensity, frequency and duration of the training, they can affect the levels of inflammatory cytokines to a different extent. The aim of this study was to investigate the effects of eight weeks Circuit Resistance Training (CRT) on some inflammatory cytokines, blood pressure and insulin resistance in pre-hypertensive obese women. For this purpose, 24 pre-hypertensive obese women (mean age: 44.73±4.43 years, body mass index: 32.39±3.8 kg/m², systolic: 13.21±0.61 mmHg and diastolic: 8.65±0.33 mmHg blood pressure levels), were conveniently selected and randomly divided into CRT training (n=12) and Control (n=12) groups. The intervention consisted of 8 weeks of circuit resistance training, with a frequency of 3 sessions per week, and each session lasted 50 to 60 minutes (15 minutes of warm-up, 30 minutes of weight training, and 10 minutes of cooling). Resistance trainings were performed with an intensity of 40% 1RM for upper body and 60% 1RM for lower body movements. Measurements and blood sampling were done pre and post 8 weeks of training. Data were analyzed using Shapiro-Wilks and analysis of variance with a 2×2 design at a significance level of p˂0.05. The results showed that 8 weeks of CRT have significant effects on body fat percent (p=0.007), Waist to Hip Ratio (p=0.017), systolic (p<0.0005) and diastolic (p=0.016) blood pressure and insulin resistance (p=0.043). However, it was not significant in the inflammatory cytokines IL-1β and TNF-α (P ≤ 0.05). The reason could be the type of exercise selected. Depending on the intensity, frequency and duration of the training, they can affect the levels of inflammatory cytokines to a different extent. https://jsb.ut.ac.ir/article_88153_8a761d6f69ee06cba77ffedaedaedb63.pdf