University of Tehran Press Sport Biosciences 2008-9325 12 4 2021 01 20 Effects of Low-Frequency High-Intensity Interval Training Combined with L-Citrulline Supplementation on Myostatin and some Physiological Parameters in Inactive Elderly Men Effects of Low-Frequency High-Intensity Interval Training Combined with L-Citrulline Supplementation on Myostatin and some Physiological Parameters in Inactive Elderly Men 493 506 80016 10.22059/jsb.2021.308706.1424 FA Faramarz Hosein Zade . MSc of Exercise Physiology, Sari Branch, Islamic Azad University, Sari, Iran Amin Farzaneh Assistant Professor of Exercise Physiology, Sari Branch, Islamic Azad University, Sari, Iran Journal Article 2020 08 22 Aging is often associated with a progressive loss of muscle strength and an increase in fat mass. High-intensity interval training may improve muscle strength, but remains largely unstudied in ageing participants. Therefore, the purpose of this study was to determine the effects of eight weeks of low-frequency high-intensity interval and L-citrulline supplementation on myostatin, aerobic power, muscular strength and endurance and body fat in older men. 30 inactive old men randomly divided into three groups: high-intensity interval training (HIT), citrolin (CIT) and high-intensity interval training+citrolin (HIT+CIT). HIIT was performed for 8 weeks and 2 sessions per week that included 30 seconds cycling exercise on ergometer (intensity of 85-90% HR reserve). CIT supplement consumed in single 8 g-dose alternateve day. Results showed that there was significant decrease for myostatin in HIT+CIT and for body fat in HIT+CIT and HIT than CIT. Muscular strength and aerobic power significant increase in HIT+CIT and HIT than CIT. HIT+CITgroup showed significant increase compared to CIT. In conclusion, low-frequency HIIT alone and combined with L-citrulline seems to induce greater improvements in muscular strength and mass factors and aerobic performance in inactive elderly men. Therefore, low-frequency HIIT+CIT can be considered as effective program to prevent or reduce sarcopenia among elderly. Aging is often associated with a progressive loss of muscle strength and an increase in fat mass. High-intensity interval training may improve muscle strength, but remains largely unstudied in ageing participants. Therefore, the purpose of this study was to determine the effects of eight weeks of low-frequency high-intensity interval and L-citrulline supplementation on myostatin, aerobic power, muscular strength and endurance and body fat in older men. 30 inactive old men randomly divided into three groups: high-intensity interval training (HIT), citrolin (CIT) and high-intensity interval training+citrolin (HIT+CIT). HIIT was performed for 8 weeks and 2 sessions per week that included 30 seconds cycling exercise on ergometer (intensity of 85-90% HR reserve). CIT supplement consumed in single 8 g-dose alternateve day. Results showed that there was significant decrease for myostatin in HIT+CIT and for body fat in HIT+CIT and HIT than CIT. Muscular strength and aerobic power significant increase in HIT+CIT and HIT than CIT. HIT+CITgroup showed significant increase compared to CIT. In conclusion, low-frequency HIIT alone and combined with L-citrulline seems to induce greater improvements in muscular strength and mass factors and aerobic performance in inactive elderly men. Therefore, low-frequency HIIT+CIT can be considered as effective program to prevent or reduce sarcopenia among elderly. https://jsb.ut.ac.ir/article_80016_39845d9e07c8c49b3926ef105c61235c.pdf