University of Tehran Press Sport Biosciences 2008-9325 9 2 2017 08 23 An Examination of the Changes in IL-15, CRP and Serum Irisin in Different Rest Intervals after a Session of Resistance Activity in the Elderly An Examination of the Changes in IL-15, CRP and Serum Irisin in Different Rest Intervals after a Session of Resistance Activity in the Elderly 271 284 63458 10.22059/jsb.2017.217509.1115 FA Ehsan Asghari Ph.D. Student of Exercise Physiology-Sport Biochemistry and Metabolism, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran Zahra Mirzendedel Ph.D. Student of Exercise Physiology-Sport Biochemistry and Metabolism, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran Journal Article 2016 11 10   The aim of this study was to evaluate changes of IL-15, CRP and serum irisin after one session of resistance activity in the elderly at different intervals with a view on the possibility of changing the muscles and improving sarcopenia. 15 elderly (mean age 63.32 ± 4.5 years, height 168.61 ± 2.33 cm and weight 78.5 ± 4.2 kg) voluntarily participated in this study. The subjects performed weight training for 45 minutes in 3 sets of 8 repetitions at 80% 1RM intensity with 2- minute rest intervals and 3-minute intervals. For statistical analysis of data, one-way ANOVA and LSD post hoc test were used (<em>P</em><0.05). The findings showed that levels of IL-15 and irisin significantly increased immediately after the test and levels of CRP and irisin significantly increased 24 hours after the test (<em>P</em><0.05). Inflammatory factors showed a significant increase 72 hours after the test compared with the period before the activity (<em>P</em><0.05). So, a session of resistance activity can elevate the levels of some of these factors in the elderly which may function as a factor which affects the improvement of muscle function and especially the control of sarcopenia in these people.     The aim of this study was to evaluate changes of IL-15, CRP and serum irisin after one session of resistance activity in the elderly at different intervals with a view on the possibility of changing the muscles and improving sarcopenia. 15 elderly (mean age 63.32 ± 4.5 years, height 168.61 ± 2.33 cm and weight 78.5 ± 4.2 kg) voluntarily participated in this study. The subjects performed weight training for 45 minutes in 3 sets of 8 repetitions at 80% 1RM intensity with 2- minute rest intervals and 3-minute intervals. For statistical analysis of data, one-way ANOVA and LSD post hoc test were used (<em>P</em><0.05). The findings showed that levels of IL-15 and irisin significantly increased immediately after the test and levels of CRP and irisin significantly increased 24 hours after the test (<em>P</em><0.05). Inflammatory factors showed a significant increase 72 hours after the test compared with the period before the activity (<em>P</em><0.05). So, a session of resistance activity can elevate the levels of some of these factors in the elderly which may function as a factor which affects the improvement of muscle function and especially the control of sarcopenia in these people.   https://jsb.ut.ac.ir/article_63458_90856c409eb9bb77b1b20c2bdf12d16f.pdf