University of Tehran Press Sport Biosciences 2008-9325 8 1 2016 03 20 The Effect of 10 Weeks of Endurance Training of Cycle Ergometer on Nesfatin-1 Levels and Insulin Resistance in Women with Type 2 Diabetes The Effect of 10 Weeks of Endurance Training of Cycle Ergometer on Nesfatin-1 Levels and Insulin Resistance in Women with Type 2 Diabetes 95 107 58244 10.22059/jsb.2016.58244 FA Mehdi Mogharnasi Asiyeh Taji Tabas Journal Article 2014 08 16 The aim of this study was to investigate the effect of 10 weeks of endurance training on nesfatin-1 levels and insulin resistance in women with type-2 diabetes. 16 women with type-2 diabetes were selected by purposive sampling method and randomly divided into experimental (<em>n</em> = 8) and control (<em>n</em> = 8) groups. The experimental group performed endurance training for 10 weeks, 3 sessions a week (with an intensity of 40-50% maximum heart rate for 20-25 minutes at the beginning of the training session, and with a gradual increase to 70-80% of maximum heart rate and 40-45 minutes in last sessions). The control group did not participate in training during the study. Blood samples were collected after 12 hours of fasting in pretest and posttest to evaluate the nesfatin-1, insulin and glucose levels. The obtained data were analyzed in SPSS 21 using Kolmogorov-Smirnov test and independent and dependent t tests with <em>α</em>P<0.05). But the nesfatin-1 and insulin levels did not significantly change in this group (<em>P</em>>0.05). Pretest and posttest changes only in glucose levels were significant in the experimental group compared with the control group (<em>P</em><0.05). In conclusion, training on a cycle ergometer is a non-drug treatment to reduce blood glucose and insulin resistance in diabetic patients. The aim of this study was to investigate the effect of 10 weeks of endurance training on nesfatin-1 levels and insulin resistance in women with type-2 diabetes. 16 women with type-2 diabetes were selected by purposive sampling method and randomly divided into experimental (<em>n</em> = 8) and control (<em>n</em> = 8) groups. The experimental group performed endurance training for 10 weeks, 3 sessions a week (with an intensity of 40-50% maximum heart rate for 20-25 minutes at the beginning of the training session, and with a gradual increase to 70-80% of maximum heart rate and 40-45 minutes in last sessions). The control group did not participate in training during the study. Blood samples were collected after 12 hours of fasting in pretest and posttest to evaluate the nesfatin-1, insulin and glucose levels. The obtained data were analyzed in SPSS 21 using Kolmogorov-Smirnov test and independent and dependent t tests with <em>α</em>P<0.05). But the nesfatin-1 and insulin levels did not significantly change in this group (<em>P</em>>0.05). Pretest and posttest changes only in glucose levels were significant in the experimental group compared with the control group (<em>P</em><0.05). In conclusion, training on a cycle ergometer is a non-drug treatment to reduce blood glucose and insulin resistance in diabetic patients. https://jsb.ut.ac.ir/article_58244_7f6c8748e3ecd94a6aaa1079e3434abc.pdf