TY - JOUR ID - 83822 TI - The Effect of 8 weeks High Intensity Interval Training on Serum levels of Asprosin, Insulin and Insulin Resistance Index in Diabetic Rats JO - Journal of Sport Biosciences JA - JSB LA - en SN - 2008-9325 AU - Pirani, Hossein AU - Choobine, Siroos AU - Rashid Lamir, Amir AU - Roostaei, Mahdi AD - Sport Physiology, Physical Education, Tehran University, Tehran, Iran. AD - Sport Physiology, Physical Education, Ferdosi University, Mashhad, Iran. Y1 - 2021 PY - 2021 VL - 13 IS - 2 SP - 167 EP - 177 KW - Asprosin KW - insulin resistance index KW - Diabets KW - Plasma Glucose KW - High Interval Intensity Training DO - 10.22059/jsb.2018.258182.1275 N2 - Type 2 diabetes is a risk factor for heart disease and has a major contribution in mortality due to cardiovascular diseases. In diabetics people, high levels of glucose is a very important issue that should be controlled. In the present study, the effect of 8-week HIIT was investigated on Serum levels of Asprosin, insulin, and insulin resistance index in diabetic rats. In this Investigation, A total of 32 male Wistar rats (mean weight, 180/23±7gr) were randomly divided into four groups of Healthy control (N=8), diabetic control (N= 8), Healthy training (N= 8) and Diabetic training (N= 8). The training group performed a 8-week High Intensity Interval Training, and 48 hours after the end of the last training session, the rats were anesthetized and euthanized. The variables of interest (Serum Levels of Asprosin, level of glucose, insulin, and insulin resistance index), were measured. Data analysis was performed using Kruskal–Wallis at significance level of p≤0.05.There was a significant difference among Asprosin (p>0/001), level of glucose (p>0/001), insulin (p>0/026), and Insulin Resistance Index (p>0/001) between the Healthy control Group, diabetic control Group, Healthy training Group and Diabetic training Group. According to the results of the present study, it seems that High Interval Intensity Training is an important strategy to decrease Asprosin, plasma glucose and Insulin resistance index in diabetics rat and it can be considered as an effective intervention method for treatment diabetes. UR - https://jsb.ut.ac.ir/article_83822.html L1 - https://jsb.ut.ac.ir/article_83822_542cc826f7a71ba183e7729b52f50446.pdf ER -