TY - JOUR ID - 66989 TI - Vascular Endothelial Growth Factor Receptor-2 and the Plmonary Vascular Volume Tracking, after 6 Weeks of High-Intensity Interval Training JO - Journal of Sport Biosciences JA - JSB LA - en SN - 2008-9325 AU - Mirdar, Shadmehr AU - Hamidiyan, Gholamreza AU - Yadegari, Mehdi AD - Professor, PhD of Exercise Physiology, Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Mazandaran, Babolsar, Iran AD - Assistant Professor, PhD of Comparative Histology, Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran AD - . PhD of Exercise Physiology, Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Mazandaran, Babolsar, Iran Y1 - 2018 PY - 2018 VL - 10 IS - 1 SP - 13 EP - 24 KW - high intensity interval training KW - Lung KW - Vascular andothelial growth factor KW - Vascular volume DO - 10.22059/jsb.2018.200362.1044 N2 - VEGF-2 has most potent angiogenic signaling associated with VEGF that So far,no has been published research in relation to the effect of exercise training on the vascular volume and it, in the lung . therefore, present study aim was investigate the effect of an high-intensity interval training period on VEGFR-2 expression and pulmonary vascular volume in male Wistar rats. This research including the experimental studies that samples its had formed 10 male Wistar rats,that to form of Randomly and equally were divided into training and control groups. Training program Was started with 25 meters per minute and with 70 meters per minute was Finished at the end of the period. In each training session, rats completed the 1-min activity with 10 repetition and work to rest ratio was 1:2. In the end, lung tissue extracted for stereologicaly and Immunohistochemistry tests. Statistical analysis whit Independent t-test, and Pearson correlation coefficient showed, significantly increase in VEGFR-2(sig: 0/001) and pulmonary vascular volume(sig: 0/042) in the exercise group compared to the control group, and positive correlation between changes in these two indicators whit exercise(sig: 0/035). In general it seems that 6 weeks of high-intensity interval training has potential to promote of lung angiogenic processes. UR - https://jsb.ut.ac.ir/article_66989.html L1 - https://jsb.ut.ac.ir/article_66989_b109a4f049a34d73bb800e4df3a1c446.pdf ER -