TY - JOUR ID - 61914 TI - The Effect of 10 Weeks of Aerobic Interval Training on Antioxidant and Oxidation Status in Type 2 Diabetic Patients JO - Journal of Sport Biosciences JA - JSB LA - en SN - 2008-9325 AU - Gaeini, Abbasali AU - Ghardashi Afousi, Alireza AD - Professor, Faculty of Physical Education and Sport Sciences, Department of Exercise Physiology, University of Tehran, Tehran, Iran AD - Ph.D. Student, Faculty of Physical Education and Sport Sciences, Department of Exercise Physiology, University of Tehran, Tehran, Iran Y1 - 2017 PY - 2017 VL - 9 IS - 1 SP - 93 EP - 108 KW - endothelial function KW - interval training KW - oxidative stress KW - type 2 diabetes DO - 10.22059/jsb.2017.61914 N2 -   The aim of this study was to investigate the effectiveness of oxidative stress status resulted from aerobic interval training in type 2 diabetic patients. 24 type 2 diabetic patients under medical treatment (mean age 50.29 ± 6.50 years and BMI 27.21 ± 0.67 kg/m2) were divided into training and control groups. The training program was conducted for 10 weeks, 3 sessions per week and 40 min. with 80% HRmax. Antioxidant indices [superoxide dismutase (SOD) and glutathione peroxidase (GPX)], oxidant index [malondialdehyde (MDA)] and nitrite/nitrate (NOx) were measured. Data were analyzed by two-way ANOVA. Results showed that aerobic interval training significantly increased NOx (P=0.004) and GPX (P=0.001) while it significantly decreased MDA (P=0.029). This training had no significant effect on SOD (P=0.063). In addition, interval training improved aerobic fitness capacity (P=0.005), but metabolic parameters showed no significant effects resulting from aerobic interval training. Aerobic interval training increased NO bioavailability through a decrease in oxidants and an increase in antioxidants. Also, intervals of exercise training improved the oxidation status and endothelial function through an increase in antioxidants and shear stress. UR - https://jsb.ut.ac.ir/article_61914.html L1 - https://jsb.ut.ac.ir/article_61914_1255d2fff6f1b89e2e74aaea5c597199.pdf ER -