ORIGINAL_ARTICLE
Identification of New Variants in Genes Related To Muscle Strength in an Elite Weightlifter Using Whole Exome Sequencing: A Case Report
Genetic factors play an important role in athletic performance and its related phenotypes such as strength, power and aerobic capacity. Whole Exome Sequencing (WES) has great potential to explore all possible deoxiribnucleotide (DNA) variants associated with physical performance. However, this new technique has not been used in sports genetics research. Therefore the aim of this case study was to report new variants in genes involved in skeletal muscles strength in an elite weightlifter using WES. After obtaining an informed contest participated in this study from a 32-year-old man, who is a member of the Iranian national weightlifting team, 5 cc of blood was taken and then DNA was extracted. DNA samples were analyzed using the WES method. WES analysis of this elite weightlifter revealed missense mutations (230845794A>G and 230845977G>A) in AGT and (148206440G>A and 148206473G>C) in ADRB2 genes. Results of WES analysis revealed missense mutations in Power/Strength related genes in this elite athlete. However more studies with larger sample sizes are needed to reveal the relationship between these variants and performance of strength athletes.
https://jsb.ut.ac.ir/article_81335_2a59b154c777291001cb5c4b5592315d.pdf
2021-12-22
399
405
10.22059/jsb.2021.319109.1456
AGT gene.Physical activity
muscle strength
Weightlifter
Muscular Hypertrophy
Bahman
Ebrahimi
m_siahkohian@uma.ac.ir
1
University of Mohaghegh Ardabili, Ardabil, Iran
LEAD_AUTHOR
Marefat
Siahkohyan
m_siahkohian@uma.ac.ir
2
University Mohaghegh Ardabili, Unirversi
AUTHOR
Ali
khazani
alikazani@yahoo.com
3
University Mohaghegh Ardabili, Unirversi
AUTHOR
sajjad
anoshirvani
sajjadanoshirvani@gmail.com
4
University Mohaghegh Ardabili, Unirversi
AUTHOR
Lotfali
Bolboli
sbolboli@yahoo.com
5
University Mohaghegh Ardabili, Unirversi
AUTHOR
Maryam
Asadi
asadi.maryamgene@yahoo.com
6
Department of Molecular Genetics, Science and Research Branch, Islamic Azad University, Fars, Iran.
AUTHOR
1. Puthucheary Z, Skipworth JR, Rawal J, Loosemore M, Van Someren K, Montgomery HE. Genetic influences in sport and physical performance. Sports medicine. 2011;41(10):845-59.
1
2. Ma F, Yang Y, Li X, Zhou F, Gao C, Li M, et al. The association of sport performance with ACE and ACTN3 genetic polymorphisms: a systematic review and meta-analysis. PloS one. 2013;8(1):e54685.
2
3. Tanisawa K, Wang G, Seto J, Verdouka I, Twycross-Lewis R, Karanikolou A, et al. Sport and exercise genomics: the FIMS 2019 consensus statement update. British journal of sports medicine. 2020;54(16):969-75.
3
4. Maciejewska-Skrendo A, Cięszczyk P, Chycki J, Sawczuk M, Smółka W. Genetic markers associated with power athlete status. Journal of human kinetics. 2019;68(1):17-36.
4
5. Gineviciene V, Jakaitiene A, Aksenov M, Aksenova A, Astratenkova ADI, Egorova E, et al. Association analysis of ACE, ACTN3 and PPARGC1A gene polymorphisms in two cohorts of European strength and power athletes. Biology of sport. 2016;33(3):199.
5
6. Zarebska A, Sawczyn S, Kaczmarczyk M, Ficek K, Maciejewska-Karlowska A, Sawczuk M, et al. Association of rs699 (M235T) polymorphism in the AGT gene with power but not endurance athlete status. The Journal of Strength & Conditioning Research. 2013;27(10):2898-903.
6
7. Kelley EF, Johnson BD, Snyder EM. Beta-2 adrenergic receptor genotype influences power output in healthy subjects. Journal of strength and conditioning research. 2017;31(8):2053.
7
8. Boulygina EA, Borisov OV, Valeeva EV, Semenova EA, Kostryukova ES, Kulemin NA, et al. Whole genome sequencing of elite athletes. Biology of Sport. 2020;37(3):295.
8
9. Corvol P, Jeunemaitre X. Molecular genetics of human hypertension: role of angiotensinogen. Endocrine reviews. 1997;18(5):662-77.
9
10. Gomez-Gallego F, Santiago C, González-Freire M, Yvert T, Muniesa CA, Serratosa L, et al. The C allele of the AGT Met235Thr polymorphism is associated with power sports performance. Applied Physiology, Nutrition, and Metabolism. 2009;34(6):1108-11.
10
11. Alves GB, Oliveira EM, Alves CR, Rached HR, Mota GF, Pereira AC, et al. Influence of angiotensinogen and angiotensin-converting enzyme polymorphisms on cardiac hypertrophy and improvement on maximal aerobic capacity caused by exercise training. European Journal of Preventive Cardiology. 2009; 16(4):92-487.
11
12. Wolfarth B, Rankinen T, Mühlbauer S, Scherr J, Boulay MR, Pérusse L, et al. Association between a β2-adrenergic receptor polymorphism and elite endurance performance. Metabolism. 2007;56(12):1649-51.
12
13. Sawczuk M, Maciejewska-Karlowska A, Cieszczyk P, Skotarczak B, Ficek K. Association of the ADRB2 Gly16Arg and Glu27Gln polymorphisms with athlete status. Journal of sports sciences. 2013;31(14):1535-44.
13
ORIGINAL_ARTICLE
Impact of Cycling Versus Sitting in Hot water and land on serum CXCL1 and IL-6 and insulin resistance in males with Metabolic Syndrome
Aim: exercise and hot water immersion is likely to more increase serum IL-6 and CXCL1 as well as insulin resistance in patients with metabolic syndrome. However, no straight investigation has been done in this area. Therefore, the aim of study was to investigate effect of an acute cycling session while immersed in hot water versus land on serum IL-6 and CXCL1 level and also insulin resistance in male patients with metabolic syndrome.Methodology: 15 males with metabolic syndrome (age: 58.4±4.17, BMI: 31.27±3.27) experienced four test sessions (with 48 hour intervals) including on cycling or inactive sitting in hot water (42 0°C) head out immersion or land conditions with a cross over design. Each of cycling sessions were included on 30 min of interval activity at 50% of MHR. Blood samples were taken before and 15 min post intervention. The variables were quantified using Elisa and Enzymatic methods and the data were analyzed by ANOVA for repeated measurements (time series method) at 0.05 statistical significance level. Results: Cycling increased serum CXCL1 only in the hot water, while IL-6 elevation was only noted during land exercise (P<0.05). However, insulin resistance was lowered in both hot water (p=0.002) and land exercise (p=0.001) sessions with no difference for this decline, between the two sessions(p=0.217). Conclusion: Cycling within the hot water compared to land, do not provide a remarkable advantage regarding the amount of induced changes in serum IL-6 and CXCL1 and even insulin resistance. However, more investigations remain to be done because of the lack of evidence and study limitations.
https://jsb.ut.ac.ir/article_86248_a175cf87b6ee7112530e325cd480e67f.pdf
2021-12-22
407
425
10.22059/jsb.2021.322625.1465
Acute Exercise
Chemokine
cytokine
Metabolism
temperature
Mohammad Taher
Jahangiri
mtaherj67@gmail.com
1
Master of Science of Exercise Physiology, Department of Sport Sciences, Faculty of Education and Psychology, Azarbaijan Shahid Madani University, Tabriz, Iran.
AUTHOR
Roghiyeh
Fakhrpour
fakhrpour@yahoo.com
2
Assistant Professor of Exercise Physiology, Department of Sport Sciences, Faculty of Education and Psychology, Azarbaijan Shahid Madani University, Tabriz, Iran.
AUTHOR
Karim
Azali Alamdari
azalof@gmail.com
3
Associate Professor of Exercise Physiology, Azarbaijan Shahid Madani University, Tabriz, Iran
LEAD_AUTHOR
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47
ORIGINAL_ARTICLE
Effect of eight weeks of continuous and high intensity interval training on UCP1 in visceral and subcutaneous white adipose tissue of obese rats
Prevalence of obesity and its related disease is considered as a major health complication worldwide. Changing the phenotype of white adipose tissue to brown following exercise is currently being studied as one of the strategies to prevent obesity. The aim of this study was to investigate the effect of eight weeks of continuous and high intensity interval training (HIIT) on UCP1 of visceral and subcutaneous white adipose tissue in obese rats. Eighteen obese rats after eight weeks of high fat diet randomly divided into control, continuous training (CT) and HIIT groups. HIIT protocol included high intensity intervals (80-110 % vVO2max) and low intensity intervals (50 % vVO2max) and CT protocol included running with )65-75 % vVO2max( intensity. 48 hours after the last training session, rats were sacrificed, visceral and subcutaneous white adipose tissue were removed and UCP1 level was assessed through western blotting method. The results showed that eight weeks of CT and HIIT increase UCP1 in visceral and subcutaneous WAT (p<0.05), and this increase were higher in HIIT group regardless of visceral or subcutaneous adipose tissue (P<0.005). It seems that HIIT induce higher increase in UCP1 protein in visceral and subcutaneous white adipose tissue, so obese individuals can use this type of training to benefit obesity prevention affects and improvement of adipose tissue function.
https://jsb.ut.ac.ir/article_78450_393f97f31605720b88142583c32b465e.pdf
2021-12-22
427
438
10.22059/jsb.2020.301401.1394
Aerobic training
Brown Fat
interval training
Obesity
UCP1
Maryam
Nourshahi
m-nourshahi@sbu.ac.ir
1
Associated professor, Faculty of Physical Education and Sport Sciences, Shahid Beheshti University, Tehran, Iran
LEAD_AUTHOR
Fatemeh
Mir Khalafzadeh
monamz3865@yahoo.com
2
MSc in exercise physiology , Faculty of Physical Education and Sport Sciences, Shahid Beheshti University, Tehran, Iran
AUTHOR
Fariba
Khodagholi
khodagholi@sbmu.ac.ir
3
Associated professor, Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
AUTHOR
Nazanin
Abuzari
n.aboozari@yahoo.com
4
PHD student, Department of Biological Sciences in Sport and Health, Faculty of Sports Sciences and Health, Shahid Beheshti University, Tehran, Iran
AUTHOR
Blüher M. Obesity: global epidemiology and pathogenesis. Nat Rev Endocrinol. 2019;15(5):288–98.
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Daneshyar S, Gharakhanlou R, Nikooie R, Forutan Y. The Effect of High-Fat Diet and Streptozotocin-Induced Diabetes and Endurance Training on Plasma Levels of Calcitonin Gene-Related Peptide and Lactate in Rats. Can J Diabetes [Internet]. 2014;38(6):461–5. Available from: http://dx.doi.org/10.1016/j.jcjd.2014.03.001
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29
ORIGINAL_ARTICLE
The Effect of Consuming Artichoke Extract with Aerobic Training on Blood Glucose and Insulin Resistance and Its Relationship with the Cognitive Status in Elderly with Mild Cognitive Impairment
Introduction: The aim of this study was to investigate the effect of 12 weeks of aerobic training and consumption of artichoke extract on blood glucose and insulin resistance and its relationship with the cognitive status in elderly with mild cognitive impairment (MCI). Methods: 40 elderly people who obtained a score between 21 and 25 from the MMSE questionnaire were randomly selected, and randomly divided into 4 groups: aerobic training, artichoke, aerobic training + artichoke, and placebo (each group 10 People) were placed. The interventions were performed for 12 weeks. The aerobic training consisted of eight minutes of running with intensity of 75 to 85% of the maximum stored heart rate in the first session. After two sessions added one minute to the running time, so that after 12 weeks, the running time reached 26 minutes. Artichoke extract was taken in capsules at a dose of 300 mg / kg body weight per day. Results: Blood glucose and insulin resistance decreased significantly in two groups of training and training + artichokes (P <0.05). Cognitive status increased significantly in the three intervention groups compared with the placebo group, which was higher in the training + artichoke group (P <0.05). As cognitive status increased, blood glucose and insulin resistance decreased (P <0.05). Conclusion: Consumption of artichoke extract along with aerobic training for 12 weeks can possibly slow the progressive course of mild cognitive impairment and may stop and prevent the onset of diabetes due to this disorder.
https://jsb.ut.ac.ir/article_85265_07f013301af3914da5ce2de20e92df3a.pdf
2021-12-22
439
450
10.22059/jsb.2021.326087.1477
Aerobic training
Artichoke
cognitive impairment
cognitive status
diabetes
Mehran
Ghahramani
mehran.physiology@gmail.com
1
Assistant Professor, Department of Exercise Physiology, Gilan-E-Gharb Branch, Islamic Azad University, Gilan-E-Gharb, Iran
LEAD_AUTHOR
Yahya
Zare
yahyazare10@yahoo.com
2
Ph.D. Student, Department of Physical Education, Jahrom Branch, Islamic Azad University, Jahrom, Iran
AUTHOR
Mohammad-Ali
Kohanpour
dr.kohanpour@gmail.com
3
Assistant Professor , Department of Exercise Physiology, Lamerd Branch, Islamic Azad University, Lamerd, Iran
AUTHOR
Sharif-zadeh QR, Moudi M, Akhbari H. Health situation of elderly supported by Imam Khomeini charity. Iran Elderly Mag. 2010; 5(17):52-60. (in persian).
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Sohrabi MB, Zolfaghari P, Mahdizade F, et al. Evaluation and comparison of cognitive state and depression in elderly admitted in sanitarium with elderly sited in personal home. Knowledge & health. 2008; 3(2):27-33. (in persian).
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Plastino, M., Fava, A., Pirritano, D., Cotronei, P., Sacco, N., Spano, A., et al. Effectes of insulin therapy on cognition impairment in patient with Alzheimer disease and diabetes mellitus type-2. Journal of the Neurological Sciences,2010; 288, 112-116.
4
Baker, L. D, Cross, D. J., Minoshima, S., Belongia, D., Watson, S., & Craft, S. Insulin resistance and Alzheimer-like reduction in regional cerebral glucose metabolism for cognitively normal adult with prediabetes or early type 2 diabetes. Archives of Neurology.2010; 68, 51-57.
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Wood, L., & Setter, S. M. Type 3 diabetes: Brain diabetes. US Pharmacist. 2010;35, 36-41.
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Kohanpour MA, Peeri M, Azarbayjani MA. The effects of aerobic exercise with lavender essence use on cognitive state and serum brain-derived neurotrophic factor levels in elderly with mild cognitive impairment. J Herbmed Pharmacol. 2017; 6(2):80-84.
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Roghani M, Baluchnejadmojarad T, Azad E.Effect of cynara scolymus feeding on learning and memory status of diabetic rats.Pajoohande. 2010; 15(2):88-94. (in persian).
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Shimoda H, Ninomiya K, Nishida N, Yoshino T, Morikawa T, et al. Anti-hyperlipidemic sesquiterpenes and new sesquiterpene glycosides from the leaves of artichoke (Cynara scolymus L.): structure requirement and mode of action. Bioorg Med Chem Lett. 2003;13(2):223-8.
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Mehmetçik G, Ozdemirler G, Koçak-Toker N, Cevikbaş U, Uysal M. Effect of pretreatment with artichoke extract on carbon tetrachloride-induced liver injury and oxidative stress. Exp Toxicol Pathol. 2008;60(6):475-80.
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Schütz K, Kammerer D, Carle R, Schieber A. Identification and quantification of caffeoylquinic acids and flavonoids from artichoke (Cynara scolymus L) heads, juice, and pomace by HPLC-DAD-ESI/MS(n). J Agric Food Chem. 2004;52(13):4090-6.
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28
ORIGINAL_ARTICLE
The effect of a six-month combined care program with garlic supplementation on coagulation factors in middle-aged men with deep vein thrombosis
The purpose of this study was to compare the effect of six-months of combined care program with garlic supplementation on coagulation factors (INR, PPT, PT) in middle-aged men with DVT. The present study was a quasi-experimental with a clinical trial design (code: IRCT20210718051924N1). Subjects were 40 men (age: 51.50 ±4.01 years, fat percentage: 28.63 ±3.24) with a history of at-least 3 years of DVT who were taking warfarin randomly divided into four groups: Combined-exercise, Combined-exercise +garlic, Garlic and Control. Combined-exercise for 24 weeks, 3 sessions per-week, first resistance training (50 to 60% 1RM) and then aerobic training (55 to 60% of the reserve-heart-rate). 1200mg daily garlic supplement was used in the form of capsules at ten o'clock in the morning. PT, PTT and INR factors were measured before and after 24 weeks. Two-way analysis of variance, paired t-test and Tukey post-hoc test were used (P<0.05). The results showed that both combined-exercise +garlic and consumption of garlic increased the PT (garlic 3.3%, p=0.004; exercise +supplement 13.3%, P=0.001) and INR (garlic 2%, p=0.013; exercise +supplement 46%, p=0.001) had a significant effect, also combined-exercise +garlic on the PTT 1.5% (p=0.014) had a significantly effect. But this wasn’t of effects in the combined-exercises (PT: p=0.355, INR: p=0.259, PTT: p=0.448) and the group Garlic was-not significant in PTT (p=0.504). It is recommended to use combined exercises with garlic consumption because of its effect on PT and INR and the important role of these factors in rebalancing homeostasis.
https://jsb.ut.ac.ir/article_85755_9edebf96fedd0466b14d08c0a214dcc6.pdf
2021-12-22
451
471
10.22059/jsb.2022.325432.1475
Combined exercise
Deep Vein Thrombosis (DVT)
Coagulation Factors
Garlic Supplement
Hamed
Saed
hamedsaed64@gmail.com
1
1. PhD student ، Department of Exercise physiology ، Kermanshah Branch، Islamic Azad University، Kermanshah، Iran
AUTHOR
Sedigheh
Hosseinpour Delavar
delavar2009@yahoo.com
2
Assistant Professor، Department of Exercise Physiology، Kermanshah Branch، Islamic Azad University، Kermanshah، Iran (Corresponding Author)
LEAD_AUTHOR
Hassan
Safikhani
safikhani2005@yahoo.com
3
Assistant Professor، Department of Corrective Exercises ، Kermanshah Branch ، Islamic Azad University ، Kermanshah ، Iran
AUTHOR
Mohammadreza
Sobhiyeh
merzasobhiyeh@yahoo.com
4
Associate Professor , Department of Vascular & Endovascular Surgery, Clinical Research Development Center, Imam Reza Hospital، Kermanshah University of Medical Sciences ، Kermanshah , Iran
AUTHOR
Terra MF, Pedrosa DG, Zoppi CC, Werneck CC, Vicente CP. Physical exercises decreases thrombus and neointima formation in atherosclerotic mice. Thrombosis research. 2019;175:21-31.
1
Evensen LH, Isaksen T, Hindberg K, Brækkan SK, Hansen JB. Repeated assessments of physical activity and risk of incident venous thromboembolism. Journal of Thrombosis and Haemostasis. 2018;16(11):2208-17.
2
Gram AS, Bladbjerg E-M, Skov J, Ploug T, Sjödin A, Rosenkilde M, et al. Three months of strictly controlled daily endurance exercise reduces thrombin generation and fibrinolytic risk markers in younger moderately overweight men. European journal of applied physiology. 2015;115(6):1331-8.
3
Yamamoto J, Ijiri Y, Ikarugi H, Otsui K, Inoue N, Sakariassen KS. Prevention of thrombotic disorders by antithrombotic diet and exercise: evidence by using global thrombosis tests. Future science OA. 2018;4(4):FSO285.
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Sandrini L, Ieraci A, Amadio P, Zarà M, Mitro N, Lee FS, et al. Physical exercise affects adipose tissue profile and prevents arterial thrombosis in BDNF Val66Met mice. Cells. 2019;8(8):875.
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Kim L, Lim Y, Park S-y, Kim YJ, Kwon O, Lee JH, et al. A comparative study of the antithrombotic effect through activated endothelium of garlic powder and tomato extracts using a rodent model of collagen and epinephrine induced thrombosis. Food science and biotechnology. 2018;27(5):1513-8.
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Menon H, Pillai A, Aussenberg-Rodriguez J, Ambrose J, Youssef I, Griffiths EA, et al. Cost reduction associated with heparin-induced thrombocytopenia panel ordering for enoxaparin versus heparin for prophylactic and therapeutic use: A retrospective analysis in a community hospital setting. Avicenna journal of medicine. 2018;8(4):133.
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Hemmati R, Dabbagh Nikukheslat S, Pourrahim Ghouroghchi A. The effect of acute endurance exercise after three different doses of garlic supplementation on coagulating factor VIII, fibrinogen and systolic and diastolic blood pressure in young athletic men. Daneshvar Medicine: Basic and Clinical Research Journal. 2021;28(5):63-74.
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Fakhar H, Tayer AH. Effect of the garlic pill in comparison with Plavix on platelet aggregation and bleeding time. Iranian journal of pediatric hematology and oncology. 2012;2(4):146.
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Gholami F, Ebrahim K, Ahmadizad S, Ebrahimi H. The Effect of Garlic Supplementation on the Main Determinants of Hemorheology in Inactive Individuals Who Underwent Endurance Training. Medical Journal of Tabriz University of Medical Sciences. 2013;34(5):53-9.
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Saastamoinen M, Särkijärvi S, Hyyppä S. Garlic (Allium sativum) supplementation improves respiratory health but has increased risk of lower hematologic values in horses. Animals. 2019;9(1):13.
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Womack C, Lawton D, Redmond L, Todd M, Hargens T. The effects of acute garlic supplementation on the fibrinolytic and vasoreactive response to exercise. Journal of the International Society of Sports Nutrition. 2015;12(1):1-8.
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San Jose MCZ, Apaga NEP, Florento L, Gan RN. Effects of aerobic exercise and training on coagulation, platelet aggregation, and plasma lipids. Vascular Disease Prevention. 2005;2(2):145-50.
14
Hilberg T, Gläser D, Reckhart C, Prasa D, Stürzebecher J, Gabriel HH. Blood coagulation and fibrinolysis after long-duration treadmill exercise controlled by individual anaerobic threshold. European journal of applied physiology. 2003;90(5):639-42.
15
Naderi R, Mohaddes G, Mohammadi M, Alihemmati A, Khamaneh A, Ghyasi R, et al. The effect of garlic and voluntary exercise on cardiac angiogenesis in diabetes: the role of MiR-126 and MiR-210. Arquivos brasileiros de cardiologia. 2018;112:154-62.
16
Kupchak BR, Creighton BC, Aristizabal JC, Dunn-Lewis C, Volk BM, Ballard KD, et al. Beneficial effects of habitual resistance exercise training on coagulation and fibrinolytic responses. Thrombosis research. 2013;131(6):e227-e34.
17
Amini A, Kordi MR, Gaini AA, Ahmadi A, Ayoubian H, Lahoorpour F. The effects of aerobic exercises on coagulation and fibrinolytic factors in inactive aged men. Scientific Journal of Kurdistan University of Medical Sciences. 2011;15(4):25-32.
18
Borch KH, Hansen-Krone I, Braekkan SK, Mathiesen EB, Njolstad I, Wilsgaard T, et al. Physical activity and risk of venous thromboembolism. The Tromsø study. Haematologica. 2010;95(12):2088.
19
Karimnia Saheb V, Tofighi A. The effect of resistance training on coagulation and fibrinolysis factors in sedentary obese children. Journal of Applied Exercise Physiology. 2019;14(28):29-40.
20
Francis RM, Romeyn CL, Coughlin AM, Nagelkirk PR, Womack CJ, Lemmer JT. Age and aerobic training status effects on plasma and skeletal muscle tPA and PAI-1. European journal of applied physiology. 2014;114(6):1229-38.
21
Lamprecht M, Moussalli H, Ledinski G, Leschnik B, Schlagenhauf A, Koestenberger M, et al. Effects of a single bout of walking exercise on blood coagulation parameters in obese women. Journal of applied physiology. 2013;115(1):57-63.
22
Ahmadizad S, Movahedi Moghadam A, Jamshidi Z, Rezaeimanesh D. The Responses of Fibrinolytic Factors to Different Resistance Exercise Protocols. Sport Physiology. 2018;10(37):139-52.
23
Bompa TO, Di Pasquale M, Cornacchia L. Serious strength training: Human Kinetics; 2012.
24
Patelis N, Karaolanis G, Kouvelos GN, Hart C, Metheiken S. The effect of exercise on coagulation and fibrinolysis factors in patients with peripheral arterial disease. Experimental Biology and Medicine. 2016;241(15):1699-707.
25
Ried K, Travica N, Sali A. The effect of aged garlic extract on blood pressure and other cardiovascular risk factors in uncontrolled hypertensives: The AGE at Heart trial. Integrated blood pressure control. 2016;9:9.
26
Ahmadizad S, Rahmani H, Khosravi N, Falakdin Z, Connes P, Daraei A. Acute responses of platelet count and ADP-induced platelet aggregation to different high intensity interval exercise modes. Clinical hemorheology and microcirculation. 2020;75(4):467-74.
27
Piccione G, Fazio F, Giudice E, Grasso F, Caola G. Exercise-Induced Changes in the Clotting Times and Fibrinolytic Activity during Official 1600 and 2 000 Meters Trot Races in the Standardbred Horses. Acta Veterinaria Brno. 2005;74(4):509-14.
28
Bhardwaj K, Verma MK, Verma N, Bhardwaj S, Mishra S. Effect of long term supplementation of active garlic allicin in reducing blood pressure in hypertensive subjects. 2017. 2017;2(3):4.
29
ORIGINAL_ARTICLE
The effect of 8 weeks of high-intensity interval training on vascular calcification index in mice with type 2 diabetes
Diabetes mellitus (DM) is a chronic metabolic disease characterized by vascular classification and impaired carbohydrates, lipids, and lack of insulin secretion or decreased sensitivity to insulin metabolic effects. on the other hand, it seems the effect of exercise on vascular classification is an important issue. In the present study, we evaluated whether 8 weeks of high-intensity interval training (HIIT) decrease vascular calcification and improvement lipid profile in rats. Main Methods: 40 Male Wistar rats were randomly divided into diabetic (T2D), exercise-diabetic (EX-T2D), exercise (EX-CON), and control (CON) groups. After 5 weeks, diabetes was induced in all the T2D and the EX-T2D group. The EX-T2D group trained for 8 weeks. Real-time PCR and colorimetric were performed to investigate the expression of RUNX2 and lipid profile Key Findings: Rat in the T2D group had a significant increase in glucose, triglyceride, cholesterol (p≤0.001), and LDL(p≤0.05) as well as deceased in insulin and HDL (p≤0.05). compared to the control group. In exercise, groups of rats had a significant decrease in RUNX2 expression compared to the control group (p≤0.05). in addition, Triglyceride and cholesterol levels were lower in the EX-T2D group compared to the diabetes group (P≤0.05). Significance: Our data demonstrate that HIIT decreased vascular calcification and improved lipid profile in a mouse model of diabetes. However, further research is required to examine potential clinical relevance.
https://jsb.ut.ac.ir/article_85373_c3ec7c631a257a458ef471afcd697433.pdf
2021-12-22
473
488
10.22059/jsb.2022.324137.1469
Vascular calcification
high intensity interval training
RUNX2
insulin
Elham
Khani Sanij
e_khanisanig@sbu.ac.ir
1
Student, Faculty of Sport Sciences and Health. Shahid Beheshti University, Tehran, Iran
AUTHOR
Khosro
Ebrahim
e_khani@ymail.com
2
Professor, Faculty of Sport Sciences and Health. Shahid Beheshti University, Tehran, Iran
LEAD_AUTHOR
Ebrahim
Rezvani
erezvani@yahoo.com
3
Professor, Department of Physiology, School of Medicine Shahid Sadoughi University of Medical Sciences. Yazd. Iran
AUTHOR
Hossein
Azizian
h_azizian@yahoo.com
4
Associated Professor, Department of Physiology, School of Medicine Shahid Sadoughi University of Medical Sciences. Yazd. Iran
AUTHOR
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Iaccarino G, Franco D, Sorriento D, Strisciuglio T, Barbato E, Morisco C. Modulation of insulin sensitivity by exercise training: implications for cardiovascular prevention. Journal of Cardiovascular Translational Research. 2021;14(2):256-70.
39
Gheibi S, Kashfi K, Ghasemi A. A practical guide for induction of type-2 diabetes in rat: Incorporating a high-fat diet and streptozotocin. Biomedicine & Pharmacotherapy. 2017;95:605-13.
40
Soori R, Ravasi A, Choobineh S, Motiee M, Sohrabi F, Baesi K, et al. The response of insulin signaling proteins IRS1 and PTP-1B to endurance, HIIT and resistance training in rats with experimental diabetes. Science & Sports. 2019;34(3):e229-e33.
41
Misra A, Alappan NK, Vikram NK, Goel K, Gupta N, Mittal K, et al. Effect of supervised progressive resistance-exercise training protocol on insulin sensitivity, glycemia, lipids, and body composition in Asian Indians with type 2 diabetes. Diabetes care. 2008;31(7):1282-7.
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43.Wang N, Liu Y, Ma Y, Wen D. High-intensity interval versus moderate-intensity continuous training: Superior metabolic benefits in diet-induced obesity mice. Life sciences. 2017;191:122-31.
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44.Esfarjani F, Rashidi F, Marandi SM. The effect of aerobic exercise on blood glucose, Lipid Profile and Apo. Journal of Ardabil University of Medical Sciences. 2013;13(2):132-41.
44
45.Rashidlamir A, Alizadeh A, Ebrahimiatri A, Dastani M. The effect of four-week period of aerobic exercise with cinnamon consumption on lipoprotein indicates and blood sugar in diabetic female patients (type 2). SSU_Journals. 2013;20(5):605-14.
45
ORIGINAL_ARTICLE
The effect of nutrition education intervention on total calorie intake, macronutrient content, iron and vitamin D status of competitive adolescent soccer players
Objective: In addition to daily calorie intake, vitamin D and iron as micronutrients are the most important in the diet of athletes, especially in adolescence. Therefore, the aim of the present study was to investigate the effect of nutrition education intervention on total caloric intake, resting levels and iron and vitamin D intake in competitive adolescent soccer players. Methods: The subjects of this study consisted of 63 competitive adolescent soccer players in the country's premier league. In order to achieve the total caloric intake and the amount of micronutrients, the subjects were recalled for three days, then blood samples were taken to achieve resting amounts of vitamin D and iron. Nutrition education intervention group (n = 41) and control group (n = 22) The experimental group was trained for 4 weeks (8 sessions of 30 minutes of applied nutrition educating followed by 10 weeks of face-to-face counseling) by attending the website and online. To examine changes within and between groups of analysis Mixed variance and dependent and independent t-tests were used. Results: The results of intragroup mixed analysis of variance test on total calories, resting levels of vitamin D and vitamin D in the diet were significant (P = 0.001). Conclusion: Nutritional education intervention significantly increases total caloric intake, carbohydrate and protein intake, resting levels of vitamin D and intake of vitamin D in the diet of competitive adolescent soccer players, but on resting values and Dietary iron intake has no effect.
https://jsb.ut.ac.ir/article_85759_87ed709c53a24ba34ceb5dce1da65eb9.pdf
2021-12-22
489
509
10.22059/jsb.2022.333258.1494
Iron
nutrition education intervention
soccer players
Sports nutrition
vitamin D
Abolfazl
Fijan
abolfazlfiji@gmail.com
1
Phd student in exercise physiology, Department of Exercise Physiology, faculty of Education and Psychology, University of Shiraz, Iran
AUTHOR
Farhad
Daryanoosh
daryanoosh@shirazu.ac.ir
2
Associate Professor of exercise physiology, Department of Exercise Physiology, faculty of Education and Psychology, University of Shiraz, Iran
LEAD_AUTHOR
Mohammad
Hemmatinafar
m.hemmatinafar@shirazu.ac.ir
3
Assistant Professor of exercise physiology, Department of Exercise Physiology, faculty of Education and Psychology, University of Shiraz, Iran
AUTHOR
Mohsen
Salesi
mhsnsls@gmail.com
4
Associate Professor of exercise physiology, Department of Exercise Physiology, faculty of Education and Psychology, University of Shiraz, Iran
AUTHOR
maryam
Koushkie Jahromi
koushkie53@yahoo.com
5
full Professor of exercise physiology, Department of Exercise Physiology, faculty of Education and Psychology, University of Shiraz, Iran
AUTHOR
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50
ORIGINAL_ARTICLE
The autonomic nervous system behavior following two weeks of moderate intensity interval training (MIIT) based body weight with surgical and N95 masks during the SARS-CoV-2 pandemic
During the COVID-19 pandemic, people are concerned about wearing a mask during physical activity and its effect on the cardiac autonomic system (ANS). The purpose of the study was the effect of 2-weeks of moderate-intensity interval training (MIIT) based body weight combined with wearing face masks (surgery against N95) on the ANS response of healthy men following the submaximal treadmill running protocol (STRP) and 5 minutes of recovery during the SARS-CoV-2 pandemic. This study,18 healthy men were randomly divided into 3 groups of 6 (surgical mask,N95 mask and Nomask) and MIIT exercises with and without surgical masks or N95 3-times a week, each session with 3-repetitions with intensity (60-70% Maximum-heart rate). Parasympathetic (RMSSD, HFn.u) and sympathetic parameters (LFn.u, LF/HF) and Change distance R-R were evaluated with electrocardiogram and Kubius software before and to 5 minutes of recovery. One-way ANOVA and Bonferroni post hoc test were used. The results showed, STRP protocol Implementation before 2-weeks of MIIT did not make a significant difference in LF, LF/HF, RMSSD, HF and mean RR values between the experimental groups (surgical mask against N95 mask) and also compared with the control group (without mask(. In addition, although the intergroup changes in sympathetic and parasympathetic indices and mean RR after 2-weeks of MIIT show relative improvement, they have not yet been statistically significant. Wearing facemasks during exercise training is safe for healthy men and 2 weeks of adaptation to interval training with face mask improves ANS performance.
https://jsb.ut.ac.ir/article_86106_d79167e0a47ff8fa1c9d344a0932eacc.pdf
2021-12-22
511
528
10.22059/jsb.2022.334247.1496
Cardiac autonomic system
face mask
Heart rate variability
interval training
Masoumeh
Fallah
mfallah8465@gmail.com
1
Ph.D degree Student, Department of Sports Physiology, Faculty of Sport Sciences, University of Mazandaran, Babolsar, Iran
AUTHOR
Valiollah
Dabidi Roshan
vdabidiroshan@yahoo.com
2
Department of Sports Physiology, Faculty of Physical EducProfessor, Department of Sports Physiology, Faculty of Sport Sciences, University of Mazandaran, Babolsar, Iran. and Athletic Performance and Health Research Center, Department of Exercise Physiology, Faculty of Sport Science, University of Mazandaran, Babolsar, Iranation and Sport Sciences, University, of Mazandaran, Babolsar, Iran.
LEAD_AUTHOR
Khadijeh
Nasiri
khadijeh_nasiri@yahoo.com
3
Assistant Professor, Department of Sports Physiology, Faculty of Sport Sciences, University of Mazandaran, Babolsar, Iran
AUTHOR
Lorwai Tan, Joshua G. Kovoor, Penny Williamson, David R. Tivey, Wendy J. Babidge, Trevor G. Collinson, et al. Personal protective equipment and evidence-based advice for surgical departments during COVID-19. ANZ J Surg 2020; 90(9):1566-1572.
1
Nicola Luigi Bragazzi, Naim Mahroum, Giovanni Damiani, Jude Dzevela Kong, Jianhong Wu. Effectiveness of community facemask use on COVID-19 epidemiological trends and patterns in Italy: evidence from a “translational” study. Infect Dis 2021; 53(4):252–254.
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