%0 Journal Article %T The Effect of 8 Weeks of Aerobic Exercises with Ergometer and Nettle Extract Supplementation on Plasma Levels of Nesfatin-1 and C-Reactive Protein in Overweight and Obese Women %J Journal of Sport Biosciences %I University of Tehran %Z 2008-9325 %A Moghadam Eftekhari, Soheila %A Vahidian Rezazadeh, Majid %A Mogharnasi, Mehdi %A Karajibani, Mansour %D 2017 %\ 05/22/2017 %V 9 %N 1 %P 123-141 %! The Effect of 8 Weeks of Aerobic Exercises with Ergometer and Nettle Extract Supplementation on Plasma Levels of Nesfatin-1 and C-Reactive Protein in Overweight and Obese Women %K C-reactive protein %K ergometer %K nesfatin-1 %K nettle %K Obesity %R 10.22059/jsb.2017.61939 %X   The aim of this study was to investigate the effect of 8 weeks of aerobic exercise with an ergometer and nettle extract supplementation on plasma levels of nesfatin-1 and C-reactive protein in overweight and obese women. A total of 46 overweight and obese women (age range of 25-45 years, BMI>25 kg/m2) were purposively selected and randomly divided into 4 groups: exercise+nettle (n=12), exercise+placebo (n=12), nettle (n=11), placebo (n=11). The nettle and placebo groups daily received 8 ml of nettle extraction and placebo solution respectively after their mail meal for 8 weeks. Aerobic exercises were conducted for 8 weeks, 3 sessions per week with an intensity of 60-75% of reserved heart rate. Blood samples were collected after 12 hours of fasting and also 48 hours after the exercises in experimental conditions. Nesfatin-1 plasma level significantly increased in exercise+nettle, exercise+placebo and nettle groups after 8 weeks of aerobic exercises and nettle supplementation (P<0.05) and exercise+nettle group had the highest increase. Weight changes, BMI and BF% showed a significant difference in all intervention groups compared to the pretest (P<0.01). Also, plasma level of CRP significantly reduced in exercise+nettle, exercise+placebo and nettle groups (P<0.05). In general, it seems that aerobic exercise on an ergometer as an effective training method with nettle extract supplementation can immunize the body against inflammatory diseases related to obesity through a reduction in CRP inflammatory marker and an increase in plasma levels of nesfatin-1. %U https://jsb.ut.ac.ir/article_61939_30b3adfa10afa865c7edfddc0d1de3d0.pdf