%0 Journal Article %T The Effects of 8 Weeks of Endurance Training on α -1A Protein of pre-Synaptic P-Q-type Calcium Channels in Fast and slow Muscles of Rats %J Journal of Sport Biosciences %I University of Tehran %Z 2008-9325 %A Gorzi, Ali %A Rajabi, Hamid %A Ghara khanlou, Reza %D 2015 %\ 09/23/2015 %V 7 %N 3 %P 363-374 %! The Effects of 8 Weeks of Endurance Training on α -1A Protein of pre-Synaptic P-Q-type Calcium Channels in Fast and slow Muscles of Rats %K FHL and Soleus Muscle %K α -1A protein %K Endurance training %K Pre-synaptic P-Q-type Calcium Channels %R 10.22059/jsb.2015.56252 %X The purpose of this study was to investigate the effects of 8 weeks of endurance training (ET) on ? -1A protein of pre-synaptic P-Q-type Calcium Channels in FHL and Soleus muscles of rats. 16 male wistar rats provided from razi institute, were randomly divided to 2 groups (Control-Sham; n=8 and Endurance Training; n= 8). Training group performed 8 weeks (5 session/week) of endurance training on animal treadmill with 10 m/min for 30 min in the first week which was gradually increased to 30 m/min for 60 min(equal to 70-80% of Vo2max) in the last week. 48 h after last session of training, FHL and Sol muscles were removed under sterilized situation by cutting on posterio-lateral side of hind limb. Measuring ?-1A protein with Western Blotting and independent t test showed that the amount of this protein insignificantly (P=0.177) increased in soleus muscles of ET group (soleus: 14.82±87.44 vs. Control: 20.20±72.57 (equal to 0/20 percent) and FHL: 7.26±70.83 vs. Control: 6.28±70.01- p=0/839). This insignificant increase in ? -1A protein in soleus muscles, may indicate to the responsiveness of pre-synaptic P-Q-type calcium channels of muscles following endurance training for improving Ach release from pre-synaptic terminal, noted in NMJ adaptations. In conclusion, it might be expressed that endurance training could be a main factor for the function of ?-1A protein in muscles and this case should be studied in future investigations with higher volume and intensities. %U https://jsb.ut.ac.ir/article_56252_8665b0699e891b7610e00f4294d709cd.pdf