The Effect of Endurance Training on Some Metabolic Parameters of Nicotinamide and Streptozotocin Induced Type 2 Diabetic Rats
Fahimieh
Kazemi
Assistant Professor, Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Alzahra University, Tehran, Iran
author
text
article
2017
per
The aim of this study was to determine the effect of endurance training on some metabolic parameters of Nicotinamide and Streptozotocin induced type 2 diabetic rats. After the induction of diabetes (injection of Nicotinamide and Streptozotocin), 24 non-obese adult male rats were divided into 3 groups: non-diabetic (n=8), trained diabetic (n=8) and control diabetic (n=8). 4 weeks after the development of diabetes, the trained diabetic group ran on a treadmill for 4 weeks. At the end of the training, intraperitoneal glucose tolerance test was performed to determine insulin sensitivity. Plasma glucose and insulin levels were measured and HOMA-IR was calculated. Independent t test and two-way ANOVA were used to analyze data. Results indicated that during 4 weeks of diabetes induction, an insignificant difference was found in body weight, food intake and fasting plasma insulin level between diabetic and non-diabetic groups, but fasting and non-fasting blood glucose level significantly increased in diabetic group compared with non-diabetic group. After 4 weeks of training, an insignificant difference was found in body weight and food intake among non-diabetic, trained diabetic and control diabetic groups, but training significantly decreased fasting plasma glucose level and HOMA-IR and significantly increased fasting plasma insulin and glucose tolerance in trained diabetic group compared with control diabetic group. Therefore, it appears that 4 weeks of endurance training had beneficial effects on some metabolic parameters of type 2 diabetic rats.
Journal of Sport Biosciences
University of Tehran
2008-9325
9
v.
4
no.
2017
457
471
https://jsb.ut.ac.ir/article_66071_fc13ca44ba27130b8e8c10404dd9636e.pdf
dx.doi.org/10.22059/jsb.2018.66071
A Comparison of Serum Serotonin Level and Some Physical Fitness Factors in Active Elderly
Farnaz
Torabi
Associate Professor, Department of Physical Education and Sport Sciences Payame Noor University, Tehran, Iran
author
Azar
Aghayari
Associate Professor, Department of Physical Education and Sport Sciences Payame Noor University, Tehran, Iran
author
Mohammad
Daneshpour
MSc in Physical Education and Sport Sciences, Payame Noor University, Tehran, Iran
author
Akram
Ramezankhani
PhD in Exercise Physiology, Faculty of Physical Education and Sport
author
text
article
2017
per
The aim of the present study was to compare the serum serotonin level and some physical fitness factors in the active elderly in Qom city. The sample comprised of male elderly over 60 years old in Qom city who were assigned to aerobic (n=15), weight training (n=15), zurkhaneh (n=15) and control (n=15) groups. In order to assess physical fitness, 4 factors including balance (single leg balance test), muscle endurance (swimming on hand), flexibility (Wells flexibility test) and power (Sargent jump) were studied. Blood serotonin was measured with ELISA test. Data were analyzed using one-way ANOVA (P<0.05). The results showed that serum serotonin levels were higher in active groups than control group (P<0.05) but there were no significant differences in blood serotonin level among active groups (P>0.05). The level of physical fitness in active subjects was better than the control group. In addition, weight training group showed a higher level of fitness in balance and muscle endurance tests (P<0.05). With regard to the results, it can be noted that sport especially weight training can have a significant effect on increasing serum serotonin level and physical fitness in the elderly.
Journal of Sport Biosciences
University of Tehran
2008-9325
9
v.
4
no.
2017
473
487
https://jsb.ut.ac.ir/article_66072_67e6c998c516346df02d5c1ce17cc79d.pdf
dx.doi.org/10.22059/jsb.2018.66072
Pre-Treatment Effect of Voluntary Physical Activity on Cardiac Damage due to the Induction of Cumulative Doses of Doxorubicin in Aging Model Rats: Histopathological Examination of Heart Tissue
Ahmad
Parsaeifar
Ph.D of Exercise Physiology department, Faculty of Sport Sciences, Mazandaran University, Babolsar, Iran
author
Zohre
Mazaheri
Assistant professor of anatomical sciences, Basic medical science research center, Histogenotechcompany, Tehran, Iran
author
valeyollah
Dabidi Roshan
. Professor of Exercise Physiology department, Faculty of Sport Sciences, Mazandaran University, Babolsar, Iran
author
text
article
2017
per
Reducing the effects of anthracyclines-induced cardiac toxicity is an effective strategy for more survival of cancer patients. This study aimed at investigating the pre-treatment effect of voluntary physical activity on cardiac damage due to the induction of cumulative doses of doxorubicin in aging model rats. 24 male Wistar rats (12 weeks old) were randomly divided into 3 groups: saline (S), doxorubicin (D), and voluntary physical activity (DWR). Ageing was induced by daily injection of D-galactose (100 mg/kg) for 9 weeks. 6 weeks of voluntary physical activity was performed on a wheel running. In the last 15 days of physical activity and D-galactose injection, doxorubicin with a cumulative dose of 15 mg/kg (or 1 mg/day) was injected. 48 hours after the end of physical activity and doxorubicin injection, the animals were euthanized and their left ventricles were severed for histological evaluation. The results showed that injection of doxorubicin insignificantly increased the apoptotic index and the ratio of heart weight to body weight while significantly decreased the ratio of fiber to the interstitial space (P<0.05). In addition, qualitative studies of the heart tissue revealed vacuolation, cell nucleus fragmentation, tissue structure cluttering, and cardiac fibers destruction. In contrast, voluntary physical activity before and during doxorubicin injection reduced these changes. Voluntary physical activity in combination with doxorubicin is an effective strategy to reduce doxorubicin-induced heart damage.
Journal of Sport Biosciences
University of Tehran
2008-9325
9
v.
4
no.
2017
489
499
https://jsb.ut.ac.ir/article_66074_f088e68e21b12abb879e111ecd9665fb.pdf
dx.doi.org/10.22059/jsb.2018.66074
The Effect of Aerobic Exercise and Calorie Restriction on Intramuscular GLUT4 and DAG Levels in Obese Male Rats
Aboozar
Jorbonian
PhD Student of Exercise Physiology, Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Guilan, Iran
author
Hamid
Mohebbi
Professor, Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Guilan, Iran
author
text
article
2017
per
Insulin resistance induced by a high fat diet has been associated with intramuscular lipid metabolites. The aim of this study was to investigate the effect of aerobic exercise, diet restriction and their combination on insulin resistance through intramuscular diacylglycerol changes in obese male rats. Sample consisted of 56 male Wistar rats (mean weight: 194.5±12.6 g). 48 rats had a high-fat diet for 18 weeks and 8 rats had normal diet. Then, high-fat diet rats were divided into control (C), aerobic Exercise (E), caloric restriction (CR), and a combination (aerobic Exercise + caloric restriction (E+C) groups. E group ran on a treadmill at 28 m. per minute for 10 weeks. In CR group, 25% of their daily caloric ingestion reduced and E+C group had aerobic exercise and caloric restriction every other day. The results indicated that rats gained weight after 18 weeks of high-fat diet (P<0.05). Also, there was a significant difference in muscle DAG and serum levels of insulin, glucose and insulin resistance index between aerobic exercise, calorie restriction and combination groups and high-fat group (P<0.05). PKC-θ levels decreased in negative energy balance groups (P>0.05). Also, there was a significant difference between E and E+C groups and high-fat diet group in GLUT4 levels (P>0.05). This study indicated that negative energy balance methods can decrease skeletal muscle DAG even along with a high-fat diet which is largely congruent with an improvement in insulin resistance.
Journal of Sport Biosciences
University of Tehran
2008-9325
9
v.
4
no.
2017
501
514
https://jsb.ut.ac.ir/article_66075_e395f37c7ca6a443bac9e71bb7c9ca87.pdf
dx.doi.org/10.22059/jsb.2018.66075
The Effect of 8 Weeks of Concurrent Training with L-Arginine Supplementation on 8-isoPGF2α, SOD, GPX and CAT in Elderly Men
Roholah
Haghshenas
Assistant Professor, Department of Exercise Physiology, Semnan University, Semnan, Iran
author
Jalil
Avandi
Assistant Professor, Department of Exercise Physiology, Semnan University, Semnan, Iran
author
Nazanin
Jalili
MSc of Exercise Physiology, Semnan University, Semnan, Iran
author
text
article
2017
per
The aim of this study was to evaluate the effect of 8 weeks of concurrent training with supplementation of L-arginine on SOD, GPX, CAT and 8-isoPGF2α in the male elderly. 44 male elderly (mean age: 67.77 ± 4.61, height: 168.38 ± 3.22 and weight: 70.45 ± 4.99) were selected voluntarily and purposively, and randomly divided into 4 groups (each group 11 subjects): training + supplements (ES), training + placebo (EP), supplement and control. Training groups completed 8 weeks of the training protocol every other day, 3 sessions per week. ES and supplementation groups daily received 1000 mg of L-arginine one hour after their breakfast and one hour before the training. ELISA method was used to measure biochemical variables and analysis of variance was used to analyze data at PP<0.001). Also, univariate analysis of variance showed the significant effect of group on every variable of oxidative stress (P<0.001). According to the findings of this study, elderly men could benefit from the effect of concurrent resistance and endurance training and consumption of 1000 mg L-arginine every day which probably reduces more oxidative stress indicator and improves their antioxidant system and could improve antioxidant defense system which improves their health.
Journal of Sport Biosciences
University of Tehran
2008-9325
9
v.
4
no.
2017
515
527
https://jsb.ut.ac.ir/article_66076_f41b11274e06eb14b3c8ed7db83f2381.pdf
dx.doi.org/10.22059/jsb.2018.66076
The Role of Orexin-A and HIF-1 Responses in Acute Mountain Sickness
Bayan
Fayazi
university razi
author
Vahid
Tadibi
Associate Professor; Department of exercise physiology, Faculty of Physical of Physical Education and Sport Sciences, Razi University Kermanshah, Kermanshah, Iran.
author
Naser
Behpoor
Associate Professor, Faculty of Sports Sciences, Department of Exercise Physiology, Razi University, Kermanshah, Iran
author
Mehdi
Hedayati
Associate Professor, Faculty of Medical Sciences, Department of Biochemistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
author
text
article
2017
per
Acute mountain sickness (AMS) caused by rapid ascent to altitudes higher than 2500 m has complex pathophysiological conditions. Therefore, the aim of the present study was to investigate hypoxia related factors in individual susceptible to acute mountain sickness. 21 healthy subjects (mean age 31.7±8.5 year) participated in this study. Fasting blood samples were collected from antecubital vein (sea level) 1 hour and 24 hours after rapid ascent to an altitude of 3550 m by a gondola lift. HIF-1 and Orexin-A were measured by ELISA method. AMS status was measured by the Lake Louise Scoring 6 hours after the exposure to a high altitude. Lake Louise Scoring showed that 11 subjects got AMS after the exposure to a high altitude (LLS≥4). The results showed that Orexin-A and HIF-1 at sea level were higher in AMS-susceptible subjects than AMS-resistant subjects. But Orexin-A and HIF-1 responses were almost higher in AMS-susceptible subjects than AMS-resistant subjects. Orexin-A and HIF-1 at sea level had an inverse relationship with AMS. An increase in these proteins in AMS-susceptible subjects was drastically higher than AMS-resistant subjects after exposure to altitude.
Journal of Sport Biosciences
University of Tehran
2008-9325
9
v.
4
no.
2017
529
541
https://jsb.ut.ac.ir/article_66092_f57248e2106e284b1cd587d18c6cff37.pdf
dx.doi.org/10.22059/jsb.2018.238223.1185
Effect of 8 Weeks of High Intensity Intermittent and Aerobic Training on Gene Expression of SOD and GPX of Heart tissue in Wistar Male Rats
Mahsa
Dehghan Manshadi
MSc of Exercise Physiology, Payame Noor University, Tehran, Iran
author
MohammadReza
Asad
Associate Professor, Department of Exercise Physiology, Payame Noor University, Tehran, Iran
author
Saeed
Naghibi
Assistant Professor, Department of Exercise Physiology, Payame Noor University, Tehran, Iran
author
text
article
2017
per
Exercise and physical activity have many benefits to improve the health, prevention, and treatment of diseases. But exercise also accuse complications should be controlled and increased oxidative stress is one of them. The aim of this study was to examine the compatibility of the devices in heart tissue antioxidant defense Wistar rats after continuous and intermittent exercise extreme here. A total of 18 male Wistar rats in the third group of high-intensity intermittent exercise (6 rats), exercise (6 rats) and control group (6 rats) were randomly assigned in a period of 8 weeks of exercise. 48 hours after the last training session, blood and tissue samples were collected by heart. The values of SOD and GPX heart tissue gene expression was determined by RT-PCR. Statistical analysis was performed using SPSS software. The results showed that SOD gene expression in both periodic and endurance training group and the control group was significantly increased. But the GPX gene expression was significantly increased only in HIT training.Exercise provides favorable changes in heart tissue and antioxidant defense system. These effects in both continuous and intermittent exercise extreme were observed. But it seems that interval training has extreme effects on antioxidant defense better.
Journal of Sport Biosciences
University of Tehran
2008-9325
9
v.
4
no.
2017
571
577
https://jsb.ut.ac.ir/article_66094_ed1ee2867d413c0090c5f5bcb99df949.pdf
dx.doi.org/10.22059/jsb.2018.243884.1210
The Effect of two Different Protocols: Post-Activation Potentiation (with and without Occlusion) on Anaerobic Performance Athletes
Akram
Sharifi Moghadam
PhD Student of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Hakim Sabzevari University, Sabzevar, Iran
author
Faezeh
Naserkhani
MSc of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Shahrood University of Technology, Shahrood, Iran
author
Sayed Ali Reza
Hosseini Kakhk
Associate Professor of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Hakim Sabzevari University, Sabzevar, Iran
author
text
article
2017
per
The aim of this study was to investigate the effect of two different protocols of post-activation potentiation on anaerobic performance of female athletes. For this purpose, in a randomized crossover design, 12 female athlete students were assigned to 4 groups: control (ordinary and traditional warm-up and then Wingate test), experiment 1 (3 sets of squat with 80% of one repetition maximum and then Wingate test), experiment 2 (3 sets of squat with 20% of one repetition maximum with vascular occlusion and then Wingate test), experiment 3 (ordinary warm-up and then Wingate test, just vascular occlusion). In order to measure the power, one repetition maximum in the squat test was used. Data were analyzed using one-way analysis of variance with repeated measures. According to the results, no significant difference was observed in the peak power, average power, and minimum power among four different groups (experiment 1, experiment 2, experimental 3 and control) (P˃0.05). The results showed that the 3 sets of squat with 20% and 80% of one repetition maximum and 10 repetitions (with or without vascular occlusion) had no effects on the output of anaerobic power in female athletes. Probably, pre-activation before power actions should be performed more strongly or with a longer rest interval.
Journal of Sport Biosciences
University of Tehran
2008-9325
9
v.
4
no.
2017
543
555
https://jsb.ut.ac.ir/article_66093_7831f56cf5467d2484b46967d12b97fd.pdf
dx.doi.org/10.22059/jsb.2017.206507.1077
The Effect of 6 Weeks of Interval Training Based on Heart Rate Deflection Point (HRDP) Extracted from D-Max Method on Blood Lactate Changes, Time to Fatigue and Performance of Young Soccer Players
Asghar
Jalali
MSc in Exercise Physiology, Department of Physical Education & Sport Sciences, University of Payame Noor, Hamedan, Iran
author
Mehdi
Abbaspoor
Assistance Professor in Exercise Physiology, Faculty of Physical Education & Sport Sciences, Shahid Bahonar University of Kerman, Kerman, Iran.
author
Mehdi
Hakimi
Ph.D in Exercise Physiology of Cardiovascular and Respiration, Department of Physical Education & Sport Science, Marivan Branch, Islamic Azad University, Marivan, Iran.
author
Maryam
Ali-Mohammadi
PhD student in Exercise Physiology of Cardiovascular and Respiration, Department of Physical Education and Sport Science, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran.
author
text
article
2017
per
The aim of this study was the effect of 6 weeks of interval training based on heart rate deflection point (HRDP) extracted from D-Max method on blood lactate, performance and time to fatigue of young soccer players. 20 soccer players volunteered to participate in this study and were randomly divided into two groups: training (n=10) and control (n=10). Control group performed their club training 3 sessions a week for 6 weeks and training group conducted the interval training with equivalent intensity of HRDP based on D-Max method in addition to their club training. The dependent and independent t tests were used to determine intragroup and intergroup differences. The results showed that time to fatigue (P=0.00) and produced lactate (P=0.02) significantly increased only in the training group, but performance was improved in both training (P=0.02) and control (P=0.04) groups. Also, the training group showed significantly better effects on lactate (P=0.01), time to fatigue (P=0.03) and performance (P=0.00) in soccer players. Generally, coaches and soccer players are recommended to use interval training with equivalent intensity of HRDP extracted from D-Max method combined with their club training in order to achieve their training goals.
Journal of Sport Biosciences
University of Tehran
2008-9325
9
v.
4
no.
2017
573
585
https://jsb.ut.ac.ir/article_66095_f1479a9782dbdd8f08e57a5331c91fe4.pdf
dx.doi.org/10.22059/jsb.2018.135375.1005
A Comparison of the Effect of One Session of Continuous and High Intensity Intermittent Training on TNF-α and VEGF Levels of Soleus Tissue in Obese Rats
Maryam
Baghery
.MSc, Faculty of Physical Education and Sport Sciences, Shahrood University of Technology, Shahrood, Semnan, Iran
author
Ali
Yunesian
Associate Professor, Faculty of Physical Education and Sport sciences, Shahrood University of Technology, Shahrood, Semnan, Iran
author
Rahimeh
Mehdizadeh
Associate Professor, Faculty of Physical Education and Sport sciences, Shahrood University of Technology, Shahrood, Semnan, Iran
author
Maryam
Nourshahi
Associate Professor, Faculty of Physical Education and Sport Sciences, Shahid Beheshti University, Tehran, Iran
author
text
article
2017
per
The aim of this study was to compare the effect of one session of continuous and high intensity intermittent training on TNF-α and VEGF levels of soleus tissue in obese rats. 45 rats (8 weeks old) were fed a high fat diet for 8 weeks. Then, 27 rats (BMI more than 0.68 gr/cm2 and weight: 320±10 gr) were randomly divided into 3 groups: control, continuous and high intensity intermittent training. Intermittent and continuous groups were familiarized with the study and their VO2max was determined for 2 weeks; then, they ran respectively with an intensity of 100% vVO2max and 65% vVO2max and the running time was calculated based on distance in the intermittent training group. Control group did not participate in any programs. Animals were dissected immediately and their soleus muscle was removed. The normality of the data was determined and one-way ANOVA was used (P≤0.05). Only the intermittent training group significantly decreased VEGF levels in comparison with the control group (P=0.001) and the continuous group (P=0.003). But TNF-α levels were not significantly different in all 3 groups. Contrary to previous speculations, high intensity intermittent training did not ascend inflammation. There is a doubt about the concern for intermittent training and inflammation increase and also VEGF levels decrease in the intermittent group in obese people which requires more research in this field.
Journal of Sport Biosciences
University of Tehran
2008-9325
9
v.
4
no.
2017
587
599
https://jsb.ut.ac.ir/article_66096_caaef74d1f44bd4bc87bfb201a77abd7.pdf
dx.doi.org/10.22059/jsb.2018.66096